Results 61 to 70 of about 29,344 (206)
Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci [PDF]
, 2020 Theileria parva is a tick‐transmitted apicomplexan protozoan parasite that infects lymphocytes of cattle and African Cape buffalo (Syncerus caffer), causing a frequently fatal disease of cattle in eastern, central and southern Africa.
Ahmed, Jabbar +13 more
core +1 more source
A Mycobacterium leprae VNTR database
Leprosy Review, 2010 A great deal of the last quarter of a century’s astonishing progress in understanding and treating human disease is attributable to the existence of public databases where information about DNA sequences, protein sequences, protein structures, human variation, etc. is stored and is freely available to all interested investigators.
openaire +2 more sources
Cell GenomicsSummary: Variable number tandem repeat (VNTR) is a pervasive and highly mutable genetic feature that varies in both length and repeat sequence. Despite the well-studied copy-number variants, the functional impacts of repeat motif polymorphisms remain ...
Sijia Zhang +13 more
doaj +1 more source
Инфекция и иммунитет, 2018 . Background. Mycobacterium avium subsp. hominissuis (MAH) is an important pathogen responsible for most of the human-associated nontuberculous mycobacteria infections.
M. Menichini +3 more
doaj +1 more source
Evolutionary history of the PER3 variable number of tandem repeats (VNTR): idiosyncratic aspect of primate molecular circadian clock. [PDF]
PLoS ONE, 2014 The PER3 gene is one of the clock genes, which function in the core mammalian molecular circadian system. A variable number of tandem repeats (VNTR) locus in the 18th exon of this gene has been strongly associated to circadian rhythm phenotypes and sleep
Flávia Cal Sabino +7 more
doaj +1 more source
Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.Abstract INTRODUCTION Alzheimer's disease (AD) is a complex neurodegenerative disorder. Hundreds of therapeutic targets have been nominated through genetic and multi‐omic studies, but effective prioritization remains a major bottleneck. METHODS We applied an integrative screening framework to assess 29 candidate targets from risk‐enriched biological ...
Gregory A. Cary +12 more
wiley +1 more source
vamos: VNTR annotation using efficient motif sets
, 2022 AbstractMotivationRoughly 3% of the human genome is composed of variable-number tandem repeats (VNTRs): tandemly repeated arrays of motifs at least six bases. These loci are highly polymorphic: over 61% of insertion and deletion variants at least 50 bases found from long-read assemblies are inside VNTRs.
Jingwen Ren, Bida Gu, Chaisson, Mark JP
openaire +1 more source
polyGR produced by CASP8 GGGAGA repeat expansion increases phosphorylation of Tau
Alzheimer's &Dementia, Volume 21, Issue S1, December 2025.Abstract Background Alzheimer's disease (AD) affects 6.5 million people in the United States with cases doubling by 2050. The accumulation of intracellular phosphorylated Tau tangles and amyloid beta plaques are pathological hallmarks of AD, however, the cause of these pathologies in most sporadic AD cases (∼95%) remains unclear.
Rodrigo Francisco Tomas +4 more
wiley +1 more source
African‐origin protective haplotype for Alzheimer's disease in APOEε4 carriers
Alzheimer's &Dementia, Volume 21, Issue S1, December 2025.Abstract Background We have reported a statistical interaction between the African ancestry specific A allele at rs10423769 and APOEε4, where the presence of the A allele is associated with a reduction in AD risk up to 75% in APOEε4 homozygotes. The mechanism by which this variant confers protection could provide insights into new therapeutics for ...
Luciana Bertholim Nasciben +22 more
wiley +1 more source