Results 71 to 80 of about 29,344 (206)

Time-and-motion tool for the assessment of working time in tuberculosis laboratories: a multicentre study [PDF]

, 2017
SETTING: Implementation of novel diagnostic assays in tuberculosis (TB) laboratory diagnosis requires effective management of time and resources. OBJECTIVE: To further develop and assess at multiple centres a time-and-motion (T&M) tool as an objective ...
Drobniewski, FA, Folkvardsen D, D, Groenheit, R, Homorodean, D, Kodmon, C, Mathys., V, Nikolayevskyy, V, Raftery, P, Roycroft, E, Van der Werf, M, Vasiliauskiene, E   +10 more
core   +1 more source

Identification and Validation of EST-Derived Molecular Markers, TRAP and VNTRs, for Banana Research [PDF]

, 2011
The advent of high-throughput sequencing technology has generated abundant information on DNA sequences for the genomes of many plant species. Expressed Sequence Tags (ESTs), which are unique DNA sequences derived from a cDNA library and therefore ...
Ferreira, C.F., Garcia, S.A.L., Kema, G.H.J., Paiva, L.V., Souza, M.T., Talebi, R., Vroh, B.I.   +6 more
core   +2 more sources

Tuberculosis transmission in Northwest of Iran: Using MIRU-VNTR, ETR-VNTR and IS6110-RFLP methods

Infection, Genetics and Evolution, 2011
Tuberculosis is the main cause for adults' death from a single infectious agent killing about 2 million people every year. Identifying the source of transmission infection is necessary to decrease tuberculosis. In this study we used IS6110-RFLP, MIRU-VNTR and ETR-VNTR methods to determine transmission dynamic of tuberculosis in Northwest of Iran from ...
Mohammad, Asgharzadeh, Hossein Samadi, Kafil, Ali Amoghi, Roudsary, Gholam Reza, Hanifi   +3 more
openaire   +2 more sources

Unveiling Aging and Alzheimer's Disease–Associated Dynamics of LINE1 DNA Content and Protein Expression in Mouse Brains

Aging Cell, Volume 24, Issue 12, December 2025.
A fundamental understanding of the Alzheimer’s disease (AD) specific trajectory of LINE1 has been limited. This study reveals an unanticipated U‐shaped trajectory of LINE1 content and expression in both wild‐type and AD mouse brains, and discerns specific changes in LINE1 content and expression tied to AD neuropathology in a sex‐different manner.
Minyan Jiang, Cheng Zhang, Juanlin Chen, Yanmei Qi, Lina Zhu, Zetong Liu, Jianfei Li, Tao Zhou, Xu Wang, Xihan Guo   +9 more
wiley   +1 more source

Genetic Heterogeneity of Francisella tularensis Subspecies mediasiatica Strains

Проблемы особо опасных инфекций
The aim of the study was to conduct comparative phylogenetic analysis of Francisella tularensis subsp. mediasiatica strains isolated in different territories of contemporary Republics of Kazakhstan, Uzbekistan, Altai Territory, and the Altai Republic in ...
V. M. Sorokin, N. V. Pavlovich, M. V. Tsimbalistova, N. V. Aronova, A. S. Vodop’yanov, R. V. Pisanov   +5 more
doaj   +1 more source

Epidemiological links between tuberculosis cases identified twice as efficiently by whole genome sequencing than conventional molecular typing: A population-based study.

PLoS ONE, 2018
BackgroundPatients with Mycobacterium tuberculosis isolates sharing identical DNA fingerprint patterns can be epidemiologically linked. However, municipal health services in the Netherlands are able to confirm an epidemiological link in only around 23 ...
Rana Jajou, Albert de Neeling, Rianne van Hunen, Gerard de Vries, Henrieke Schimmel, Arnout Mulder, Richard Anthony, Wim van der Hoek, Dick van Soolingen   +8 more
doaj   +1 more source

Genes of the serotonergic and dopaminergic pathways and their interaction affect the expression of Behavioural and Psychological Symptoms in Dementia (BPSD). [PDF]

, 2009
Although there is evidence for the involvement of genes of serotonergic and dopaminergic systems in the manifestation of the Behavioural and Psychological Symptoms in Dementia (BPSD), genetic association studies are contradictory.
Belinda Martin, Brian Lawlord, Gillian Hamilton, John Powell, Julie Williams, Michael Gill, Michael J. Owen, Michelle Lupton, Nicola Archer, Paul hollingworth, Petroula Proitsi, Simon Lovestone, Suzanne Reeves   +12 more
core   +1 more source

ClassTR: Classifying Within-Host Heterogeneity Based on Tandem Repeats with Application to Mycobacterium tuberculosis Infections. [PDF]

, 2015
Genomic tools have revealed genetically diverse pathogens within some hosts. Within-host pathogen diversity, which we refer to as "complex infection", is increasingly recognized as a determinant of treatment outcome for infections like tuberculosis ...
Chindelevitch, L, Cohen, T, Colijn, C, Moodley, P, Wilson, D   +4 more
core   +3 more sources

Gene polymorphisms in primary biliary cirrhosis: association with the disease and hepatic osteopathy [PDF]

, 2007
Genetic factors have been implicated in the pathogenesis of osteoporosis, a common disorder in primary biliary cirrhosis (PBC). Estrogen receptor-alpha gene (ER- ), vitamin-D-receptor gene (VDR) and IL-1-receptor-antagonist gene (IL-1RN) are all ...
Bajnok, Éva, Ferenci, Péter, Lakatos, Péter, Lakatos, Péter László, Szalay, Ferenc, Takács, István, Willheim-Polli, Claudia   +6 more
core  

Long‐read sequencing reveals genomic and epigenomic variation in the dark genome of human Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 11, November 2025.
Abstract INTRODUCTION Faulty DNA repair and epigenetic regulation contribute to neurodegeneration in Alzheimer's disease. Long‐read sequencing enables analysis of “dark regions” that are difficult to study via traditional sequencing methodologies.
Paulino Ramirez, Wenyan Sun, Shiva Kazempour Dehkordi, Habil Zare, Giovanni Pascarella, Piero Carninci, Bernard Fongang, Kevin F. Bieniek, Bess Frost   +8 more
wiley   +1 more source