Results 21 to 30 of about 32,223 (242)
The Multicellular Effects of VDAC1 N-Terminal-Derived Peptide
Biomolecules, 2022 The mitochondrial voltage-dependent anion channel-1 (VDAC1) protein functions in a variety of mitochondria-linked physiological and pathological processes, including metabolism and cell signaling, as well as in mitochondria-mediated apoptosis.
Uttpal Anand +8 more
doaj +1 more source
A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings
Micromachines, 2020 Ion channel proteins play important roles in various cell functions, making them attractive drug targets. Artificial lipid bilayer recording is a technique used to measure the ion transport activities of channel proteins with high sensitivity and ...
Minako Hirano +6 more
doaj +1 more source
High conductance anion channel in Schwann cell vesicles from rat spinal roots [PDF]
, 1992 Potassium uptake, possibly together with chloride, is one of the presumed functions of Schwann cells in the peripheral nervous system. However, the presence of chloride channels has not been demonstrated in adult Schwann cells.
Quasthoff, Stefan +5 more
core +1 more source
Hepatitis C virus replication requires integrity of mitochondria-associated ER membranes
JHEP Reports, 2023 Background & Aims: Chronic HCV infection causes cellular stress, fibrosis and predisposes to hepatocarcinogenesis. Mitochondria play key roles in orchestrating stress responses by regulating bioenergetics, inflammation and apoptosis.
Sarah Duponchel +13 more
doaj +1 more source
Advanced Science, 2023 Cadmium (Cd) is a high‐risk pathogenic toxin for hepatic diseases. Excessive mitophagy is a hallmark in Cd‐induced hepatotoxicity. However, the underlying mechanism remains obscure.
Cong Liu +9 more
doaj +1 more source
Anion channel sensitivity to cytosolic organic acids implicates a central role for oxaloacetate in integrating ion flux with metabolism in stomatal guard cells [PDF]
, 2011 Stomatal guard cells play a key role in gas exchange for photosynthesis and in minimizing transpirational water loss from plants by opening and closing the stomatal pore.
Yizhou Wang +5 more
core +1 more source
Cell demise inhibited: Unexpected liaisons between mitochondria and IκΒα
Molecular & Cellular Oncology, 2021 IκΒα (the protein product of NFKBIA gene) has widely been considered a pro- apoptotic factor due to its ability to inhibit the anti-apoptotic transcription factor NFκB.
Evangelos Pazarentzos
doaj +1 more source
Antioxidants, 2023 Olive mill wastewater, a by-product of the olive oil industry, represents an important resource, rich in bioactive compounds with antioxidant activity.
Paola Foti +6 more
doaj +1 more source
Silencing VDAC1 Expression by siRNA Inhibits Cancer Cell Proliferation and Tumor Growth In Vivo
Molecular Therapy: Nucleic Acids, 2014 Alterations in cellular metabolism and bioenergetics are vital for cancer cell growth and motility. Here, the role of the mitochondrial protein voltage-dependent anion channel (VDAC1), a master gatekeeper regulating the flux of metabolites and ions ...
Tasleem Arif +4 more
doaj +1 more source
Protocol: optimised electrophyiological analysis of intact guard cells from arabidopsis [PDF]
, 2012 Genetic resources available for Arabidopsis thaliana make this species particularly attractive as a model for molecular genetic studies of guard cell homeostasis, transport and signalling, but this facility is not matched by accessible tools for ...
Adrian Hills +19 more
core +1 more source