Results 31 to 40 of about 91,818 (287)

A Single Talent Immunogenic Membrane Antigen and Novel Prognostic Predictor: voltage-dependent anion channel 1 (VDAC1) in Pancreatic Cancer. [PDF]

Sci Rep, 2016
Immunogenic membrane antigens associated with multiple biological functions of human cancer cells, have significant value in molecule diagnosis and targeted therapy. Here we screened immunogenic membrane antigens in pancreatic cancer by immunobloting IgG
Wang W, Zhang T, Zhao W, Xu L, Yang Y, Liao Q, Zhao Y.   +6 more
europepmc   +2 more sources

Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8 [PDF]

BMC Cancer, 2010
Background Activation of the extrinsic apoptosis pathway by tumour necrosis factor related apoptosis inducing ligand (TRAIL) is a novel therapeutic strategy for treating cancer that is currently under clinical evaluation.
Longley Daniel B, Paul Ian, Liberante Fabio, Chacko Alex D, Fennell Dean A   +4 more
doaj   +4 more sources

Mitochondrial Proteomics Approach Reveals Voltage-Dependent Anion Channel 1 (VDAC1) as a Potential Biomarker of Gastric Cancer

Cellular Physiology and Biochemistry, 2015
Background/Aims: Gastric cancer (GC) remains the second leading cause of cancer-related deaths in the world. Successful early cancer detection is hampered by lack of highly sensitive and specific biomarkers.
Wen Gao, Jing Xu, Fuqiang Wang, Long Zhang, Rui Peng, Yunxia Zhu, Qiyun Tang, Jindao Wu   +7 more
doaj   +3 more sources

Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop. [PDF]

J Biol Chem, 2014
Background: The voltage-dependent anion channel 1 (VDAC1) is identified as a receptor of human plasminogen kringle 5 (K5), but the role and mechanisms of VDAC1 in K5-induced endothelial cell (EC) apoptosis remain elusive.
Li L, Yao YC, Gu XQ, Che D, Ma CQ, Dai ZY, Li C, Zhou T, Cai WB, Yang ZH, Yang X, Gao GQ.   +11 more
europepmc   +2 more sources

VDAC1 protein derived from extracellular vesicles promotes paclitaxel resistance in gastric cancer through autophagy and mitophagy [PDF]

Cancer Biology & Medicine
Objective: Paclitaxel (PTX), a conventional second-line therapeutic agent for advanced gastric cancer (GC), exhibits compromised clinical efficacy due to acquired chemoresistance in patients, the molecular mechanisms of which remain poorly elucidated ...
Yanna Bi, Sisi Wei, Zhe Zhang, Yuqing Wang, Yang Wen, Hongquan Wang, Kexin Li, Cong Zhang, Yumin Wang, Lianmei Zhao, Guogui Sun   +10 more
doaj   +2 more sources

Mechanism of translation control of the alternative Drosophila melanogaster Voltage Dependent Anion-selective Channel 1 mRNAs [PDF]

Scientific Reports, 2018
The eukaryotic porin, also called the Voltage Dependent Anion-selective Channel (VDAC), is the main pore-forming protein of the outer mitochondrial membrane.
Loredana Leggio, F. Guarino, Andrea Magrì, R. Accardi-Gheit, S. Reina, Valeria Specchia, F. Damiano, M. Tomasello, Massimo Tommasino, A. Messina   +9 more
semanticscholar   +5 more sources

Arabidopsis voltage-dependent anion channel 1 (AtVDAC1) is required for female development and maintenance of mitochondrial functions related to energy-transaction. [PDF]

PLoS ONE, 2014
The voltage-dependent anion channels (VDACs), prominently localized in the outer mitochondrial membrane, play important roles in the metabolite exchange, energy metabolism and mitochondria-mediated apoptosis process in mammalian cells.
Xiaodi Pan, Ziwei Chen, Xueyong Yang, Guoqin Liu   +3 more
doaj   +2 more sources

The voltage-dependent anion selective channel 1 (VDAC1) topography in the mitochondrial outer membrane as detected in intact cell.

PLoS ONE, 2013
Voltage-Dependent Anion selective Channel maintains the permeability of the outer mitochondrial membrane and is relevant in bioenergetic metabolism and apoptosis. The structure of the protein was shown to be a β-barrel formed by 19 strands.
Marianna F Tomasello, Francesca Guarino, Simona Reina, Angela Messina, Vito De Pinto   +4 more
doaj   +4 more sources

Pentenediol-Type Compounds Specifically Bind to Voltage-Dependent Anion Channel 1 in Saccharomyces cerevisiae Mitochondria.

Biochemistry, 2019
Voltage-dependent anion channel 1 (VDAC1) situated in the outer mitochondrial membrane regulates the transfer of various metabolites and is a key player in mitochondria-mediated apoptosis.
Yufu Unten, M. Murai, Takenori Yamamoto, Akira Watanabe, Naoya Ichimaru, Shunsuke Aburaya, Wataru Aoki, Y. Shinohara, H. Miyoshi   +8 more
semanticscholar   +3 more sources

Voltage-Dependent Anion Channel 1 Interacts with Ribonucleoprotein Complexes To Enhance Infectious Bursal Disease Virus Polymerase Activity. [PDF]

J Virol, 2017
Han C, Zeng X, Yao S, Gao L, Zhang L, Qi X, Duan Y, Yang B, Gao Y, Liu C, Zhang Y, Wang Y, Wang X.   +12 more
europepmc   +2 more sources