Results 11 to 20 of about 13,998 (216)
Involvement of voltage-dependent anion channel (VDAC) in dengue infection. [PDF]
Sci Rep, 2016 AbstractDuring infection, dengue virus (DENV) proteins interact with host cellular constituents promoting the remodeling of the cell to facilitate virus production. While a number of interacting proteins have been identified for DENV non-structural proteins, far fewer interacting partners have been identified for the DENV structural proteins.
Jitobaom K, Tongluan N, Smith DR.
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Aspirin induces cell death by directly modulating mitochondrial voltage-dependent anion channel (VDAC). [PDF]
Sci Rep, 2017 AbstractAspirin induces apoptotic cell death in various cancer cell lines. Here we showed that silencing of VDAC1 protected HeLa cells from aspirin-induced cell death. Compared to the wild type cells, VDAC1 knocked down cells showed lesser change of mitochondrial membrane potential (Δψm), upon aspirin treatment.
Tewari D +3 more
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The Biogenesis Process of VDAC – From Early Cytosolic Events to Its Final Membrane Integration
Frontiers in Physiology, 2021 Voltage dependent anion-selective channel (VDAC) is the most abundant protein in the mitochondrial outer membrane. It is a membrane embedded β-barrel protein composed of 19 mostly anti-parallel β-strands that form a hydrophilic pore.
Anasuya Moitra, Doron Rapaport
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Cepharanthine induces ROS stress in glioma and neuronal cells via modulation of VDAC permeability
Saudi Pharmaceutical Journal, 2020 Cepharanthine (CEP) is a bisbenzylisoquinoline alkaloid. Molecular dynamics studies show that CEP interacts with Voltage-dependent anion channel (VDAC), inducing the voltage-independent channel narrowing.
Karolina Cierluk +6 more
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Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs
Frontiers in Physiology, 2020 There is accumulating evidence that endogenous steroids and non-polar drugs are involved in the regulation of mitochondrial physiology. Many of these hydrophobic compounds interact with the Voltage Dependent Anion Channel (VDAC).
Tatiana K. Rostovtseva +3 more
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Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. [PDF]
PLoS ONE, 2011 Tubulin was recently found to be a uniquely potent regulator of the voltage-dependent anion channel (VDAC), the most abundant channel of the mitochondrial outer membrane, which constitutes a major pathway for ATP/ADP and other metabolites across this ...
Kely L Sheldon +4 more
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The intrinsically disordered N-terminus of the voltage-dependent anion channel.
PLoS Computational Biology, 2021 The voltage-dependent anion channel (VDAC) is a critical β-barrel membrane protein of the mitochondrial outer membrane, which regulates the transport of ions and ATP between mitochondria and the cytoplasm.
Jordane Preto, Isabelle Krimm
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Arabidopsis Voltage-Dependent Anion Channels (VDACs): Overlapping and Specific Functions in Mitochondria [PDF]
Cells, 2020 Voltage-dependent anion channels (VDACs) are essential components of the mitochondrial outer membrane. VDACs are involved in the exchange of numerous ions and molecules, from ATP to larger molecules such as tRNAs, and are supposed to adjust exchanges in response to cell signals and stresses. Four major VDACs have been identified in Arabidopsis thaliana.
Mickaële Hemono +5 more
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Tumor Biology, 2020 The exchange of metabolites between mitochondria and cytosol occurs through pores formed by voltage-dependent anion channel proteins. Voltage-dependent anion channels appear to be master regulators of mitochondrial bioenergetics and the intracellular ...
Paweł Jóźwiak +8 more
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Biomolecules, 2021 It has become impossible to review all the existing literature on Voltage-Dependent Anion selective Channel (VDAC) in a single article. A real Renaissance of studies brings this protein to the center of decisive knowledge both for cell physiology and ...
Vito De Pinto
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