Porin 1 Modulates Autophagy in Yeast
Cells, 2021 Autophagy is a cellular recycling program which efficiently reduces the cellular burden of ageing. Autophagy is characterised by nucleation of isolation membranes, which grow in size and further expand to form autophagosomes, engulfing cellular material ...
Filomena Broeskamp +9 more
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In Silico Exploration of Alternative Conformational States of VDAC
Molecules, 2023 VDAC (Voltage-Dependent Anion-selective Channel) is the primary metabolite pore in the mitochondrial outer membrane (OM). Atomic structures of VDAC, consistent with its physiological “open” state, are β-barrels formed by 19 transmembrane (TM) β-strands ...
Carmen Mannella
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Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1 [PDF]
, 2017 Voltage-dependent anion channel-1 (VDAC1) is a highly regulated β-barrel membrane protein that mediates transport of ions and metabolites between the mitochondria and cytosol of the cell.
Abramson, Jeff +10 more
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VDAC: Voltage Dependant Anion Channel
The FASEB Journal, 2011 VDAC (Voltage Dependent Anion Channel) is a channel protein located on the outer mitochondrial membrane. It regulates mitochondria functions and cell respiration through the exchange of molecules between the cytoplasm and the organelle, such as ADP, ATP, anions, cations, and other small, hydrophilic molecules.
Patrick Jordan +18 more
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Solute channels of the outer membrane: from bacteria to chloroplasts [PDF]
, 2007 Chloroplasts, unique organelles of plants, originated from endosymbiosis of an ancestor of today's cyanobacteria with a mitochondria-containing host cell. It is assumed that the outer envelope membrane, which delimits the chloroplast from the surrounding
Aljamal J.A. +8 more
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Co-Incubation of Human Spermatozoa with Anti-VDAC Antibody Reduced Sperm Motility
Cellular Physiology and Biochemistry, 2014 Background: Voltage-dependent anion channel (VDAC), a channel protein, exists in the outer mitochondrial membrane of somatic cells and is involved in multiple physiological and pathophysiological processes.
Bianjiang Liu +9 more
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Flexibility of the N-Terminal mVDAC1 Segment Controls the Channel’s Gating Behavior [PDF]
, 2012 Since the solution of the molecular structures of members of the voltage dependent anion channels (VDACs), the N-terminal α-helix has been the main focus of attention, since its strategic location, in combination with its putative conformational ...
Anastasia Salisowski +8 more
core +3 more sources
Frontiers in Oncology, 2021 Metabolic plasticity is the ability of the cell to adjust its metabolism to changes in environmental conditions. Increased metabolic plasticity is a defining characteristic of cancer cells, which gives them the advantage of survival and a higher ...
Leenu Reinsalu +12 more
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Magic Angle Spinning Nuclear Magnetic Resonance Characterization of Voltage-Dependent Anion Channel Gating in Two-Dimensional Lipid Crystalline Bilayers [PDF]
, 2014 National Institutes of Health (U.S.) (EB001960)National Institutes of Health ...
Andreas, Loren +8 more
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Voltage dependent anion channel-1 (VDAC-1) as an anti-cancer target [PDF]
Cancer Biology & Therapy, 2010 Commentary to:Down-regulation of voltage-dependent anion channel-1 expression by RNA interference prevents cancer cell growth in vivoInbar Koren, Ziv Raviv and Varda Shoshan ...
Saroj P, Mathupala, Peter L, Pedersen
openaire +2 more sources