Results 11 to 20 of about 5,739 (164)

The Dual Role of the 16mer Motif Within the 3' Untranslated Region of the Variant Surface Glycoprotein of Trypanosoma brucei. [PDF]

Mol Microbiol
A fully conserved 16mer motif is required in the silent VSG to trigger efficient silencing of the expression site (ES)‐resident VSG and a successful exchange of the VSG coat. ABSTRACT The variant surface glycoprotein (VSG) of African trypanosomes is essential for the survival of bloodstream form parasites.
Bakari-Soale M, Batram C, Zimmermann H, Jones NG, Engstler M.   +4 more
europepmc   +2 more sources

MRI Analysis of Cardiac Fat, Abdominal Adiposity and Cardiac Function After Vertical Sleeve Gastrectomy in Youth With Type 2 Diabetes. [PDF]

Pediatr Obes
ABSTRACT Background Adolescents with youth‐onset type 2 diabetes (YO‐T2D) have an increased risk for cardiometabolic complications. The impact of vertical sleeve gastrectomy (VSG) on fat distribution and cardiac morphology/function in YO‐T2D is unknown.
Dobbs TJ, Gutierrez L, Hu HH, Hunter KS, Fonseca B, Browne L, Winter D, Cree MG, Pyle L, Hills-Dunlap JL, Reusch JEB, Kelsey MM, Inge TH, Bjornstad P, Nadeau KJ.   +14 more
europepmc   +2 more sources

A comparative study of single-loop VSG and multi-loop VSG

Energy Reports, 2022
The large-scale access of renewable energy generation has caused weak grid and a series of instability issues. Virtual synchronous generators (VSG), which can support the voltage and frequency, are gaining increasing applications. At present, there are two main types of VSG. One is single-loop VSG containing only a power control loop.
Feng Han, Xing Zhang, Zixuan Guo, Jilei Wang, Xinxin Fu, Bo Gao   +5 more
openaire   +2 more sources

Pedal to the Metal: Nuclear Splicing Bodies Turbo-Charge VSG mRNA Production in African Trypanosomes

Frontiers in Cell and Developmental Biology, 2022
The African trypanosome Trypanosoma brucei is a parasite of the mammalian bloodstream and tissues, where an antigenically variable Variant Surface Glycoprotein (VSG) coat protects it from immune attack.
James Budzak, Gloria Rudenko
doaj   +1 more source

SUMOylation by the E3 ligase TbSIZ1/PIAS1 positively regulates VSG expression in Trypanosoma brucei. [PDF]

PLoS Pathogens, 2014
Bloodstream form trypanosomes avoid the host immune response by switching the expression of their surface proteins between Variant Surface Glycoproteins (VSG), only one of which is expressed at any given time.
Diana López-Farfán, Jean-Mathieu Bart, Domingo I Rojas-Barros, Miguel Navarro   +3 more
doaj   +1 more source

Universal Virtual Synchronous Generator Based on Extended Virtual Inertia to Enhance Power and Frequency Response

Energies, 2023
Virtual synchronous generators (VSG) are considered a new generation of grid-friendly inverters with the same inertial support characteristics as synchronous generators (SG). However, the inertia support comes with the side effects of power and frequency
Hao Liu, Bo Yang, Song Xu, Mingjian Du, Shuai Lu   +4 more
doaj   +1 more source

Control of Variant Surface Glycoprotein Expression by CFB2 in Trypanosoma brucei and Quantitative Proteomic Connections to Translation and Cytokinesis

mSphere, 2022
Variant surface glycoproteins (VSGs) coat parasitic African trypanosomes and underpin antigenic variation and immune evasion. These VSGs are superabundant virulence factors that are subject to posttranscriptional gene expression controls mediated via the
Gustavo Bravo Ruiz, Michele Tinti, Melanie Ridgway, David Horn   +3 more
doaj   +1 more source

Transcription Dependent Loss of an Ectopically Expressed Variant Surface Glycoprotein during Antigenic Variation in Trypanosoma brucei

mBio, 2022
In the mammalian host, Trypanosoma brucei is coated in a single-variant surface glycoprotein (VSG) species. Stochastic switching of the expressed VSG allows the parasite to escape detection by the host immune system.
Emilia Jane McLaughlin, Karinna Rubio-Pena, Annick Dujeancourt-Henry, Lucy Glover   +3 more
doaj   +1 more source

Modification of Control System Based on Virtual Synchronous Generator with Feedforward Control for Power Converters of Distributed Generation [PDF]

E3S Web of Conferences
An important development trend for modern power systems is the application of control algorithms for power converters based on a virtual synchronous generator (VSG), which can mimic the characteristics of the conventional synchronous generation and ...
Askarov Alisher, Ufa Ruslan, Suvorov Aleksey, Kievets Anton   +3 more
doaj   +1 more source

PI(3,4,5)P3 allosteric regulation of repressor activator protein 1 controls antigenic variation in trypanosomes

eLife, 2023
African trypanosomes evade host immune clearance by antigenic variation, causing persistent infections in humans and animals. These parasites express a homogeneous surface coat of variant surface glycoproteins (VSGs).
Abdoulie O Touray, Rishi Rajesh, Tony Isebe, Tamara Sternlieb, Mira Loock, Oksana Kutova, Igor Cestari   +6 more
doaj   +1 more source