Results 11 to 20 of about 81,482 (329)
The Journal of Cell Biology, 2006 ![Graphic][1] Extended organelle form (left) is needed for later correct function. CUTLER/ELSEVIERFollowing blood vessel injury, long strings of multimeric von Willebrand's factor (VWF) act as a scaffold for platelets to help staunch bleeding. The VWF strings, 100-μm long or more,
William A. Wells
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Blood, 2006 Comment on Lisman et al, page [3753][1] In this issue of Blood , Lisman and colleagues report on the identification of the VWF-binding site within collagen III: of 57 triple-helical peptides spanning the whole triple-helical domain, one single 27-residue collagen III sequence, with an essential 9-
Hans Deckmyn, Karen Vanhoorelbeke
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Clinical significance of ADAMTS-13/vWF axis in pregnant women at different trimesters of gestation
Акушерство, гинекология и репродукция, 2023 Introduction. The pandemic of a novel coronavirus infection has demonstrated the importance of assessing the ADAMTS-13/vWF axis in patients with COVID-19, because a decline in this ratio mirrors disease severity.
K. N. Grigoreva +14 more
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VWF clearance: it’s glycomplicated [PDF]
Blood, 2018 In this issue of Blood , Ward et al demonstrate that a loss of sialic acids turns von Willebrand factor (VWF) into a ligand for the scavenger-receptor macrophage galactose-type lectin (MGL ...
Denis, Cécile, Lenting, Peter
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VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease [PDF]
Blood, 2013 Key Points VWFpp/VWF:Ag and FVIII:C/VWF:Ag ratios define the pathophysiological mechanisms that play a role in VWD and various VWF mutations. A high VWFpp/VWF:Ag ratio indicates increased clearance of VWF and a high FVIII:C/VWF:Ag ratio decreased synthesis of VWF.
J. Eikenboom +11 more
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Акушерство, гинекология и репродукция, 2021 Numerous studies have proven a close relationship between inflammatory diseases and the state of hypercoagulability. In fact, thromboembolic complications represent one of the main causes of disability and mortality in acute and chronic inflammatory ...
A. D. Makatsariya +14 more
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, 2017 Von Willebrand Disease (VWD) is a blood clotting disorder characterized by low levels of the Von Willebrand Factor (VWF) in the blood. VWF is functions to bind platelets and promote clotting of the blood when vascular injury occurs.
Misla David, Ramon
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Nucleosomes and neutrophil extracellular traps in septic and burn patients [PDF]
, 2017 NETosis is a host defense mechanism associated with inflammation and tissue damage. Experimental models show that platelets and von Willebrand factor (VWF) are key elements for intravascular NETosis. We determined NETosis in septic and burn patients at 1
Carestia, Agostina +8 more
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Global Thrombosis Test - a possible monitoring system for the effects and safety of dabigatran [PDF]
, 2015 © Otsui et al. 2015BACKGROUND: Dabigatran is an alternative to warfarin (WF) for the thromboprophylaxis of stroke in patients with non-valvular atrial fibrillation (NVAF). The advantage of dabigatran over WF is that monitoring is not required; however, a
Gorog, Diana A +8 more
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Application of microfluidic devices in studies of thrombosis and hemostasis
Platelets, 2017 Due to the importance of fluid flow during thrombotic episodes, it is quite appropriate to study clotting and bleeding processes in devices that have well-defined fluid shear environments.
Changjie Zhang, Sriram Neelamegham
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