Results 11 to 20 of about 47,865 (277)

Pathogenetic and prognostic significance of inflammation and altered ADAMTS-13/vWF axis in patients with severe COVID-19

Акушерство, гинекология и репродукция, 2022
Introduction. Currently, endothelial dysfunction caused by inflammation and immunothrombosisis considered as one of the crucial mechanisms in developing the SARS-CoV-2 virus-mediated coronavirus disease 2019 (COVID-19). A mass endothelial damage followed
V. O. Bitsadze, J. Kh. Khizroeva, J.-Ch. Gris, S. Schulman, A. S. Shkoda, M. V. Tretyakova, N. A. Makatsariya, E. V. Slukhanchuk, L. L. Pankratyeva, M. I. Petrovskiy, I. V. Mashechkin, D. V. Blinov, V. I. Tsibizova, Z. K. Gadaeva, S. S. Panshin, N. V. Samburova, A. D. Makatsariya   +16 more
doaj   +1 more source

Clinical significance of assessing ADAMTS-13 and von Willebrand factor level in COVID-19 convalescent pregnant women

Акушерство, гинекология и репродукция, 2023
Introduction. Coronavirus infection is associated with severe endotheliopathy, thromboinflammation and immunothrombosis leading to excessive release of von Willebrand factor (vWF) multimers from Weibel–Palade bodies, which can affect activity of ADAMTS ...
N. R. Gashimova, K. N. Grigoreva, V. O. Bitsadze, L. L. Pankratyeva, J. Kh. Khizroeva, M. V. Tretyakova, Ya. M. Shammut, E. Iu. Iupatov, V. I. Tsibizova, J.-K. Gris, D. V. Blinov, A. D. Makatsariya   +11 more
doaj   +1 more source

Qualitative low VWF [PDF]

Blood

openalex   +2 more sources

Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

Biology Open, 2021
Arf GTPase-Activating proteins (ArfGAPs) mediate the hydrolysis of GTP bound to ADP-ribosylation factors (Arfs), which are critical to form transport intermediates.
Asano Watanabe, Hikari Hataida, Naoya Inoue, Kosuke Kamon, Keigo Baba, Kuniaki Sasaki, Rika Kimura, Honoka Sasaki, Yuka Eura, Wei-Fen Ni, Yuji Shibasaki, Satoshi Waguri, Koichi Kokame, Yoko Shiba   +13 more
doaj   +1 more source

Functioning of the ADAMTS-13/vWF axis and its clinical significance

Акушерство, гинекология и репродукция, 2023
Advances in biology have allowed us to substantially deepen our knowledge about hemostasis functioning both in health and disease. ADAMTS-13 (a disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13) and von Willebrand factor (vWF)
K. N. Grigoreva, N. R. Gashimova, V. O. Bitsadze, L. L. Pankratyeva, J. Kh. Khizroeva, M. V. Tretyakova, J.-C. Gris, A. E. Malikova, D. V. Blinov, V. I. Tsibizova, N. D. Degtyareva, S. V. Martirosyan, A. D. Makatsariya   +12 more
doaj   +1 more source

VWF clearance: it’s glycomplicated [PDF]

Blood, 2018
In this issue of Blood , Ward et al demonstrate that a loss of sialic acids turns von Willebrand factor (VWF) into a ligand for the scavenger-receptor macrophage galactose-type lectin (MGL ...
Denis, Cécile, Lenting, Peter
openaire   +2 more sources

Clinical significance of ADAMTS-13/vWF axis in pregnant women at different trimesters of gestation

Акушерство, гинекология и репродукция, 2023
Introduction. The pandemic of a novel coronavirus infection has demonstrated the importance of assessing the ADAMTS-13/vWF axis in patients with COVID-19, because a decline in this ratio mirrors disease severity.
K. N. Grigoreva, N. R. Gashimova, V. O. Bitsadze, L. L. Pankratyeva, J. Kh. Khizroeva, M. V. Tretyakova, V. I. Tsibizova, N. D. Degtyareva, A. V. Mulenkova, J.-C. Gris, M. V. Kvaratskheliia, E. Grandone, F. E. Yakubova, D. V. Blinov, A. D. Makatsariya   +14 more
doaj   +1 more source

VWF propeptide and ratios between VWF, VWF propeptide, and FVIII in the characterization of type 1 von Willebrand disease [PDF]

Blood, 2013
Key Points VWFpp/VWF:Ag and FVIII:C/VWF:Ag ratios define the pathophysiological mechanisms that play a role in VWD and various VWF mutations. A high VWFpp/VWF:Ag ratio indicates increased clearance of VWF and a high FVIII:C/VWF:Ag ratio decreased synthesis of VWF.
J. Eikenboom, A.B. Federici, R. J. Dirven, G. Castaman, F. Rodeghiero, U. Budde, R. Schneppenheim, J. Batlle, M. T. Canciani, J. Goudemand, I. Peake, A. Goodeve   +11 more
openaire   +4 more sources

Neutrophil extracellular traps: a role in inflammation and dysregulated hemostasis as well as in patients with COVID-19 and severe obstetric pathology

Акушерство, гинекология и репродукция, 2021
Numerous studies have proven a close relationship between inflammatory diseases and the state of hypercoagulability. In fact, thromboembolic complications represent one of the main causes of disability and mortality in acute and chronic inflammatory ...
A. D. Makatsariya, E. V. Slukhanchuk, V. O. Bitsadze, J. Kh. Khizroeva, M. V. Tretyakova, N. A. Makatsariya, S. V. Akinshina, A. S. Shkoda, L. L. Pankratyeva, G. C. Di Renzo, G. Rizzo, K. N. Grigorieva, V. I. Tsibizova, J.-C. Gris, I. Elalamy   +14 more
doaj   +1 more source

Application of microfluidic devices in studies of thrombosis and hemostasis

Platelets, 2017
Due to the importance of fluid flow during thrombotic episodes, it is quite appropriate to study clotting and bleeding processes in devices that have well-defined fluid shear environments.
Changjie Zhang, Sriram Neelamegham
doaj   +1 more source