Results 71 to 80 of about 1,291 (151)
Campbell Systematic Reviews, Volume 21, Issue 1, March 2025.Abstract Background People with disabilities are consistently falling behind in educational outcomes compared to their peers without disabilities, whether measured in terms of school enrolment, school completion, mean years of schooling, or literacy levels.
Xanthe Hunt +3 more
wiley +1 more source
Cohesin acetylation and Wapl‐Pds5 oppositely regulate translocation of cohesin along DNA
The EMBO Journal, 2016 Cohesin is a ring-shaped protein complex that plays a crucial role in sister chromatid cohesion and gene expression. The dynamic association of cohesin with chromatin is essential for these functions. However, the exact nature of cohesin dynamics, particularly cohesin translocation, remains unclear.
Mai Kanke +3 more
openaire +3 more sources
Crystal Structure of the Cohesin Gatekeeper Pds5 and in Complex with Kleisin Scc1
Cell Reports, 2016 Sister chromatid cohesion is mediated by cohesin, whose Smc1, Smc3, and kleisin (Scc1) subunits form a ring structure that entraps sister DNAs. The ring is opened either by separase, which cleaves Scc1 during anaphase, or by a releasing activity ...
Byung-Gil Lee +6 more
doaj +1 more source
Cohesin Can Remain Associated with Chromosomes during DNA Replication
Cell Reports, 2017 To ensure disjunction to opposite poles during anaphase, sister chromatids must be held together following DNA replication. This is mediated by cohesin, which is thought to entrap sister DNAs inside a tripartite ring composed of its Smc and kleisin (Scc1)
James D.P. Rhodes +5 more
doaj +1 more source
PLoS Genetics, 2019 Sister chromatid cohesion on chromosome arms is essential for the segregation of homologous chromosomes during meiosis I while it is dispensable for sister chromatid separation during mitosis.
Kiran Challa +5 more
doaj +1 more source
Frontiers in Plant Science, 2015 Maintenance and precise regulation of sister chromatid cohesion is essential for faithful chromosome segregation during mitosis and meiosis. Cohesin cofactors contribute to cohesin dynamics and interact with cohesin complexes during cell cycle.
Mónica ePradillo +6 more
doaj +1 more source
Wapl antagonizes cohesin binding and promotes Polycomb-group silencing inDrosophila
Development, 2012 Wapl protein regulates binding of the cohesin complex to chromosomes during interphase and helps remove cohesin from chromosomes at mitosis. We isolated a dominant mutation in wapl (waplAG) in a screen for mutations that counteract silencing mediated by an engrailed Polycomb-group response element.
Melissa D, Cunningham +6 more
openaire +3 more sources
PLoS ONE, 2011 For self-renewal, embryonic stem cells (ESCs) require the expression of specific transcription factors accompanied by a particular chromosome organization to maintain a balance between pluripotency and the capacity for rapid differentiation. However, how
Anja Nitzsche +11 more
doaj +1 more source