Results 21 to 30 of about 108,453 (351)

Warburg effect—damping of electromagnetic oscillations [PDF]

open access: yesElectromagnetic Biology and Medicine, 2017
Mitochondrial dysfunction is a central defect in cells creating the Warburg and reverse Warburg effect cancers. However, the link between mitochondrial dysfunction and cancer has not yet been clearly explained. Decrease of mitochondrial oxidative energy production to about 50 % in comparison with healthy cells may be caused by inhibition of pyruvate ...
Jiří, Pokorný   +2 more
openaire   +2 more sources

Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect. [PDF]

open access: yes, 2015
Epidemiological and biochemical studies show that the sporadic forms of Alzheimer's disease (AD) are characterized by the following hallmarks: (a) An exponential increase with age; (b) Selective neuronal vulnerability; (c) Inverse cancer comorbidity. The
Demetrius, L.A.   +2 more
core   +4 more sources

Reciprocal regulation of LOXL2 and HIF1α drives the Warburg effect to support pancreatic cancer aggressiveness

open access: yesCell Death and Disease, 2021
Hypoxic microenvironment is common in solid tumors, particularly in pancreatic ductal adenocarcinoma (PDAC). The Warburg effect is known to facilitate cancer aggressiveness and has long been linked to hypoxia, yet the underlying mechanism remains largely
Rongkun Li   +11 more
doaj   +1 more source

A separation of the reactions in photosynthesis by means of intermittent light [PDF]

open access: yes, 1932
Experiments on photosynthesis in intermittent light have been made on two occasions. Brown and Escombe, in 1905, made use of a rotating sector to study the effect of light intensity on the photosynthesis of leaves.
Arnold, William, Emerson, Robert
core   +2 more sources

Uncoupling the Warburg effect from cancer [PDF]

open access: yesProceedings of the National Academy of Sciences, 2010
A remarkable trademark of most tumors is their ability to break down glucose by glycolysis at a vastly higher rate than in normal tissues, even when oxygen is copious. This phenomenon, known as the Warburg effect, enables rapidly dividing tumor cells to generate essential biosynthetic building blocks such as nucleic acids, amino acids, and lipids from ...
Najafov, Ayaz, Alessi, Dario R.
openaire   +3 more sources

Dr. Otto Heinrich Warburg—Survivor of Ethical Storms

open access: yesRambam Maimonides Medical Journal, 2015
Otto Heinrich Warburg (1883–1970; not to be confused with the Zionist of the same name) was a member of an illustrious Jewish family, known for some five centuries.
George M. Weisz
doaj   +1 more source

New horizons in modulating the radio-sensitivity of head and neck cancer - 100 years after Warburg’ effect discovery

open access: yesFrontiers in Oncology, 2022
Tumor radiation resistance along with chemotherapy resistance is one of the main causes of therapeutic failure of radiotherapy-treated head and neck cancers.
Camil Ciprian Mireștean   +5 more
doaj   +1 more source

The Aurora kinase inhibitor AT9283 inhibits Burkitt lymphoma growth by regulating Warburg effect [PDF]

open access: yesPeerJ, 2023
Objective To investigate the effect of the kinase inhibitor AT9283 on Burkitt lymphoma (BL) cells and elucidate the underlying mechanisms. Methods The effect of AT9283 on the proliferation of BL cell lines was tested using the MTT assay.
Kaiming Jiang   +6 more
doaj   +2 more sources

Mechanism of Warburg Effect and Its Effect on Tumor Metastasis

open access: yesChinese Journal of Lung Cancer, 2015
Cancer cells exhibit altered glucose metabolism characterized by a preference for aerobic glycolysis even when the oxygen content is normal, a phenomenon termed “Warburg effect”. However the definite molecular mechanisms of Warburg effect remains unclear,
Huijun WEI   +4 more
doaj   +1 more source

CircFOXK2 promotes hepatocellular carcinoma progression and leads to a poor clinical prognosis via regulating the Warburg effect

open access: yesJournal of Experimental & Clinical Cancer Research, 2023
Background The Warburg effect is well-established to be essential for tumor progression and accounts for the poor clinical outcomes of hepatocellular carcinoma (HCC) patients.
Jun Zheng   +16 more
doaj   +1 more source

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