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Deciphering White Adipose Tissue Heterogeneity [PDF]
Biology, 2019 Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body.
Quyen Luong, Jun Huang, Kevin Y. Lee
doaj +5 more sources
Nutrition & Metabolism, 2022 Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado +6 more
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An integrated single cell and spatial transcriptomic map of human white adipose tissue
Nature Communications, 2023 Single-cell studies of human white adipose tissue (WAT) provide insights into the specialized cell types in the tissue. Here the authors combine publicly available and newly generated high-resolution and bulk transcriptomic results from multiple human ...
Lucas Massier +27 more
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White adipose tissue mitochondrial metabolism in health and in obesity [PDF]
Obesity Reviews, 2019 White adipose tissue is one of the largest organs of the body. It plays a key role in whole‐body energy status and metabolism; it not only stores excess energy but also secretes various hormones and metabolites to regulate body energy balance.
S. Heinonen +3 more
semanticscholar +3 more sources
CD47 differentially regulates white and brown fat function [PDF]
Biology Open, 2020 Mechanisms that enhance energy expenditure are attractive therapeutic targets for obesity. Previously we have demonstrated that mice lacking cd47 are leaner, exhibit increased energy expenditure, and are protected against diet-induced obesity.
Heather Norman-Burgdolf +3 more
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AdipoAtlas: A reference lipidome for human white adipose tissue
Cell Reports Medicine, 2021 Summary: Obesity, characterized by expansion and metabolic dysregulation of white adipose tissue (WAT), has reached pandemic proportions and acts as a primer for a wide range of metabolic disorders.
Mike Lange +6 more
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Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning [PDF]
Heliyon, 2022 Background: Browning of white adipose tissue is associated with elevated resting metabolic rates and is considered to be one of the indispensable causes of hypermetabolism in burn patients.
Meng Zhang +8 more
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Neuroimmune regulation of white adipose tissues [PDF]
The FEBS Journal, 2021 The white adipose tissues (WAT) are located in distinct depots throughout the body. They serve as an energy reserve, providing fatty acids for other tissues via lipolysis when needed, and function as an endocrine organ to regulate systemic metabolism. Their activities are coordinated through intercellular communications among adipocytes and other cell ...
Xinmin Qian +3 more
openaire +3 more sources
Biology of Sex Differences, 2022 Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2.
Jacob E. Pruett +9 more
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Epicardial Adipose Tissue Segmentation from CT Images with A Semi-3D Neural Network [PDF]
2021 International Symposium ELMAR, 2021, pp. 87-90, 2022 Epicardial adipose tissue is a type of adipose tissue located between the heart wall and a protective layer around the heart called the pericardium. The volume and thickness of epicardial adipose tissue are linked to various cardiovascular diseases. It is shown to be an independent cardiovascular disease risk factor.
arxiv +1 more source