Results 1 to 10 of about 240,259 (361)

Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition

open access: yesBiology of Sex Differences, 2022
Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2.
Jacob E. Pruett   +9 more
doaj   +1 more source

Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases

open access: yesNutrition & Metabolism, 2022
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado   +6 more
doaj   +1 more source

Dynamic changes in the transcriptome of tRNA-derived small RNAs related with fat metabolism

open access: yesScientific Data, 2023
The prevalence of obesity and overweight is steadily rising, posing a significant global challenge for humanity. The fundamental cause of obesity and overweight lies in the abnormal accumulation of adipose tissue.
Tianci Liao   +6 more
doaj   +1 more source

Effects of a Phosphodiesterase inhibitor on the Browning of Adipose Tissue in Mice

open access: yesBiomedicines, 2022
Cilostazol is a selective inhibitor of phosphodiesterase type 3 (PDE3) that increases intracellular cyclic adenosine monophosphate (cAMP), which plays a critical role in the development of the beige phenotype and the activation of its thermogenic program
Da Hea Seo   +6 more
doaj   +1 more source

Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue

open access: yesFrontiers in Endocrinology, 2020
Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann   +14 more
doaj   +1 more source

miR-34a-/- mice are susceptible to diet-induced obesity [PDF]

open access: yes, 2016
Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H.   +7 more
core   +1 more source

The Emerging Importance of Mitochondria in White Adipocytes: Neither Last nor Least [PDF]

open access: yesEndocrinology and Metabolism, 2023
The growing recognition of mitochondria’s crucial role in the regulation of white adipose tissue remodeling and energy balance underscores its significance. The marked metabolic diversity of mitochondria provides the molecular and cellular foundation for
Juan Cai, Fenfen Wang, Mengle Shao
doaj   +1 more source

Differential Tissue Response to Growth Hormone in Mice [PDF]

open access: yes, 2018
Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R.   +4 more
core   +2 more sources

Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease

open access: yesFrontiers in Cardiovascular Medicine, 2020
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date several types of adipose tissue have been identified, namely white, brown, and beige, that reside in various specific anatomical locations throughout the body. The
Alan Chait, Laura J. den Hartigh
doaj   +1 more source

miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit [PDF]

open access: yes, 2013
Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue.
Chen, Y.   +6 more
core   +1 more source

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