Results 1 to 10 of about 498,134 (401)

Adipose Tissue Distribution, Inflammation and Its Metabolic Consequences, Including Diabetes and Cardiovascular Disease

Frontiers in Cardiovascular Medicine, 2020
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date several types of adipose tissue have been identified, namely white, brown, and beige, that reside in various specific anatomical locations throughout the body. The
Alan Chait, Laura J. den Hartigh
doaj   +1 more source

PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]

, 2017
How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M, Feng, Chu, He, Anyuan, Hsu, Fong-Fu, Lodhi, Irfan J, Park, Hongsuk, Semenkovich, Clay F, Song, Haowei, Tan, Min   +8 more
core   +3 more sources

Pre- and postnatal adipose tissue development in farm animals: from stem cells to adipocyte physiology [PDF]

, 2016
To view supplementary material for this article, please visit http://dx.doi.org/10.1017/S1751731116000872Both white and brown adipose tissues are recognized to be differently involved in energy metabolism and are also able to secrete a variety of ...
Bonnet, Muriel, Gondret, Florence, Louveau, Isabelle, Perruchot, Marie-Hélène   +3 more
core   +3 more sources

There and Back Again: Leptin Actions in White Adipose Tissue

International Journal of Molecular Sciences, 2020
Leptin is a hormone discovered almost 30 years ago with important implications in metabolism. It is primarily produced by white adipose tissue (WAT) in proportion to the amount of fat. The discovery of leptin was a turning point for two principle reasons:
N. Martínez-Sánchez
semanticscholar   +1 more source

Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning

Heliyon, 2022
Background: Browning of white adipose tissue is associated with elevated resting metabolic rates and is considered to be one of the indispensable causes of hypermetabolism in burn patients.
Meng Zhang, Peilang Yang, Tianyi Yu, Martin C. Harmsen, Min Gao, Dan Liu, Yan Shi, Yan Liu, Xiong Zhang   +8 more
doaj   +1 more source

Hypoxia and adipose tissue function and dysfunction in obesity [PDF]

, 2013
The rise in the incidence of obesity has led to a major interest in the biology of white adipose tissue. The tissue is a major endocrine and signalling organ, with adipocytes, the characteristic cell type, secreting a multiplicity of protein factors ...
Di Girolamo M, Hales CN, Himms-Hagen J, Kyrou I, Matsumoto S, Mise H, Ostlund RE, Paul Trayhurn, Pérez de Heredia F, Trayhurn P, Wang GL, World Health Organisation, Yokota T   +12 more
core   +1 more source

Sulforaphane induces adipocyte browning and promotes glucose and lipid utilization [PDF]

, 2016
Scope: Obesity is closely related to the imbalance of white adipose tissue storing excess calories, and brown adipose tissue dissipating energy to produce heat in mammals.
Bao, Yong P., Chen, Fen, Chen, Shi Y, Fu, Jian F, Shan, Yu J, Wang, An S, Yao, An J, Zhang, Hui Q, Zhang, Xiao H, Zhao, Jin S, Zhou, Zu Q   +10 more
core   +1 more source

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms [PDF]

, 2015
Objectives: The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.
Clark, S., Contarino, A., Cota, D., Diz-Chaves, Y., Fanelli, F., Grammatopoulos, Dimitris, Lehnert, Hendrik, Lu, B., Markovic, Danijela, Penicaud, L., Tabarin, A.   +10 more
core   +3 more sources

Calcium sensing receptor as a novel mediator of adipose tissue dysfunction: mechanisms and potential clinical implications

Frontiers in Physiology, 2016
Obesity is currently a serious worldwide public health problem, reaching pandemic levels. For decades, dietary and behavioral approaches have failed to prevent this disease from expanding, and health authorities are challenged by the elevated prevalence ...
Roberto Bravo, Roberto Bravo, Pamela Mattar, Pamela Mattar, Ximena Diaz, Sergio Lavandero, Sergio Lavandero, Sergio Lavandero, Mariana Cifuentes   +8 more
doaj   +1 more source

miR-34a-/- mice are susceptible to diet-induced obesity [PDF]

, 2016
Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H., Caslake, Muriel, Collier, Andrew, Donnelly, Iona, Holmes, William, Kurowska-Stolarska, Mariola, Lavery, Christopher A., Miller, Ashley M.   +7 more
core   +1 more source