Results 11 to 20 of about 254,914 (259)

Deciphering White Adipose Tissue Heterogeneity [PDF]

Biology, 2019
Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body.
Quyen Luong, Jun Huang, Kevin Y. Lee
doaj   +3 more sources

Mitochondrial function and oxidative stress in white adipose tissue in a rat model of PCOS: effect of SGLT2 inhibition [PDF]

Biology of Sex Differences, 2022
Highlights 1. Androgen excess in PCOS model is associated with decreased markers of mitochondrial content in both subcutaneous and visceral white adipose tissue. 2.
Jacob E. Pruett, Steven J. Everman, Ngoc H. Hoang, Faridah Salau, Lucy C. Taylor, Kristin S. Edwards, Jonathan P. Hosler, Alexandra M. Huffman, Damian G. Romero, Licy L. Yanes Cardozo   +9 more
doaj   +2 more sources

Obesity, white adipose tissue and cancer. [PDF]

FEBS J
White adipose tissue (WAT) is crucial for whole‐body energy homeostasis and plays an important role in metabolic and hormonal regulation. While healthy WAT undergoes controlled expansion and contraction to meet the body's requirements, dysfunctional WAT in conditions like obesity is characterized by excessive tissue expansion, alterations in lipid ...
Solsona-Vilarrasa E, Vousden KH.
europepmc   +3 more sources

White Adipose Tissue in Obesity-Associated HFpEF [PDF]

JACC: Basic to Translational Science
Summary: Obesity and hypertension are prevalent comorbidities in heart failure with preserved ejection fraction (HFpEF). Increased adiposity is implicated in its pathophysiology. We investigated changes in white adipose tissue (WAT) in obesity-associated
María Valero-Muñoz, PhD, Eng Leng Saw, PhD, Hannah Cooper, BA, David R. Pimentel, MD, Flora Sam, MD   +4 more
doaj   +2 more sources

White adipose tissue uptake on 18F FDG PET/CT: A case report

Radiology Case Reports
Three distinct types of adipose tissue have been characterized: brown, white, and beige. Brown adipose tissue (BAT) is typically found in specific regions including the anterior cervical, supraclavicular, axillary, and paravertebral areas.
Maria Andrea Parra Corral, MD, Jesus R. Diaz, MD   +1 more
doaj   +2 more sources

Diet-Induced Browning of White Adipose Tissue: Molecular Targets, Mechanisms, and Therapeutic Potential. [PDF]

Curr Issues Mol Biol
Yang ZD, Chen JW, Mei YX, Xia XW, Gong YJ, Ding WJ.   +5 more
europepmc   +3 more sources

Neuroimmune regulation of white adipose tissues [PDF]

The FEBS Journal, 2021
The white adipose tissues (WAT) are located in distinct depots throughout the body. They serve as an energy reserve, providing fatty acids for other tissues via lipolysis when needed, and function as an endocrine organ to regulate systemic metabolism. Their activities are coordinated through intercellular communications among adipocytes and other cell ...
Xinmin Qian, Xia Meng, Shan Zhang, Wenwen Zeng   +3 more
openaire   +2 more sources

Browning of the white adipose tissue regulation: new insights into nutritional and metabolic relevance in health and diseases

Nutrition & Metabolism, 2022
Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado, Gabriel Pasquarelli-do-Nascimento, Debora Santos da Silva, Gabriel Ribeiro Farias, Igor de Oliveira Santos, Luana Borges Baptista, Kelly Grace Magalhães   +6 more
doaj   +1 more source

Dynamic changes in the transcriptome of tRNA-derived small RNAs related with fat metabolism

Scientific Data, 2023
The prevalence of obesity and overweight is steadily rising, posing a significant global challenge for humanity. The fundamental cause of obesity and overweight lies in the abnormal accumulation of adipose tissue.
Tianci Liao, Mailin Gan, Yuhang Lei, Yan Wang, Lei Chen, Linyuan Shen, Li Zhu   +6 more
doaj   +1 more source

Effects of a Phosphodiesterase inhibitor on the Browning of Adipose Tissue in Mice

Biomedicines, 2022
Cilostazol is a selective inhibitor of phosphodiesterase type 3 (PDE3) that increases intracellular cyclic adenosine monophosphate (cAMP), which plays a critical role in the development of the beige phenotype and the activation of its thermogenic program
Da Hea Seo, Eugene Shin, Yong-ho Lee, Se-Eun Park, Ki Taek Nam, Jae-woo Kim, Bong-Soo Cha   +6 more
doaj   +1 more source