Results 11 to 20 of about 116,442 (217)
Neuroimmune regulation of white adipose tissues [PDF]
The FEBS Journal, 2021 The white adipose tissues (WAT) are located in distinct depots throughout the body. They serve as an energy reserve, providing fatty acids for other tissues via lipolysis when needed, and function as an endocrine organ to regulate systemic metabolism. Their activities are coordinated through intercellular communications among adipocytes and other cell ...
Xinmin Qian +3 more
openaire +3 more sources
Deciphering White Adipose Tissue Heterogeneity [PDF]
Biology, 2019 Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body. Adipose tissue is organized into discrete depots throughout the body, and these depots are differentially associated with insulin resistance and ...
Kevin Y. Lee +4 more
openaire +4 more sources
Hysteresis of White Adipose Tissue
Open Journal of Endocrine and Metabolic Diseases, 2015 Objective: This study was performed to analyze the modifications within adipose tissue during calorie restriction and more specifically to state whether hysteresis occurs during fat mass reduction. Method: Rats male Wistar increased their body weight by 130 g under control conditions and were then submitted to a calorie restriction (CR) at 30% or 60 ...
Geloen, Alain +3 more
openaire +8 more sources
miR-34a-/- mice are susceptible to diet-induced obesity [PDF]
, 2016 Objective: MicroRNA (miR)−34a regulates inflammatory pathways, and increased transcripts have been observed in serum and subcutaneous adipose of subjects who have obesity and type 2 diabetes.
Baker, Andrew H. +7 more
core +1 more source
miR-155 regulates differentiation of brown and beige adipocytes via a bistable circuit [PDF]
, 2013 Brown adipocytes are a primary site of energy expenditure and reside not only in classical brown adipose tissue but can also be found in white adipose tissue.
Chen, Y. +6 more
core +1 more source
Differential Tissue Response to Growth Hormone in Mice [PDF]
, 2018 Growth hormone (GH) has been shown to act directly on multiple tissues throughout the body. Historically, it was believed that GH acted directly in the liver and only indirectly in other tissues via insulin‐like growth hormone 1 (IGF‐1).
Banerjee, Ronadip R. +4 more
core +2 more sources
Brown vs white adipocytes: The PPARγ coregulator story [PDF]
, 2010 The development of adipose tissue is a process which involves the concerted cooperation of numerous transcription factors together with their coactivators and corepressors.
Kalkhoven, Eric, Koppen, Arjen
core +1 more source
Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming [PDF]
, 2017 BACKGROUND: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in
Czech, Michael P +11 more
core +4 more sources
Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]
, 2014 Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin +10 more
core +2 more sources
PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources