Results 11 to 20 of about 240,259 (361)
Deciphering White Adipose Tissue Heterogeneity [PDF]
Biology, 2019 Adipose tissue not only stores energy, but also controls metabolism through secretion of hormones, cytokines, proteins, and microRNAs that affect the function of cells and tissues throughout the body.
Quyen Luong, Jun Huang, Kevin Y. Lee
doaj +4 more sources
Obesity, white adipose tissue and cancer. [PDF]
FEBS JWhite adipose tissue (WAT) is crucial for whole‐body energy homeostasis and plays an important role in metabolic and hormonal regulation. While healthy WAT undergoes controlled expansion and contraction to meet the body's requirements, dysfunctional WAT in conditions like obesity is characterized by excessive tissue expansion, alterations in lipid ...
Solsona-Vilarrasa E, Vousden KH.
europepmc +3 more sources
Neuroimmune regulation of white adipose tissues [PDF]
The FEBS Journal, 2021 The white adipose tissues (WAT) are located in distinct depots throughout the body. They serve as an energy reserve, providing fatty acids for other tissues via lipolysis when needed, and function as an endocrine organ to regulate systemic metabolism. Their activities are coordinated through intercellular communications among adipocytes and other cell ...
Xinmin Qian +3 more
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Hysteresis of White Adipose Tissue
Open Journal of Endocrine and Metabolic Diseases, 2015 Objective: This study was performed to analyze the modifications within adipose tissue during calorie restriction and more specifically to state whether hysteresis occurs during fat mass reduction. Method: Rats male Wistar increased their body weight by 130 g under control conditions and were then submitted to a calorie restriction (CR) at 30% or 60 ...
Geloen, Alain +3 more
openaire +5 more sources
PexRAP inhibits PRDM16-mediated thermogenic gene expression [PDF]
, 2017 How the nuclear receptor PPARγ regulates the development of two functionally distinct types of adipose tissue, brown and white fat, as well as the browning of white fat, remains unclear.
Dean, John M +8 more
core +3 more sources
Pre- and postnatal adipose tissue development in farm animals: from stem cells to adipocyte physiology [PDF]
, 2016 To view supplementary material for this article, please visit http://dx.doi.org/10.1017/S1751731116000872Both white and brown adipose tissues are recognized to be differently involved in energy metabolism and are also able to secrete a variety of ...
Bonnet, Muriel +3 more
core +3 more sources
Brown vs white adipocytes: The PPARγ coregulator story [PDF]
, 2010 The development of adipose tissue is a process which involves the concerted cooperation of numerous transcription factors together with their coactivators and corepressors.
Kalkhoven, Eric, Koppen, Arjen
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Otopetrin 1 protects mice from obesity-associated metabolic dysfunction through attenuating adipose tissue inflammation. [PDF]
, 2014 Chronic low-grade inflammation is emerging as a pathogenic link between obesity and metabolic disease. Persistent immune activation in white adipose tissue (WAT) impairs insulin sensitivity and systemic metabolism, in part, through the actions of ...
Cheng, Ji-Xin +10 more
core +2 more sources
Frontiers in Physiology, 2016 Obesity is currently a serious worldwide public health problem, reaching pandemic levels. For decades, dietary and behavioral approaches have failed to prevent this disease from expanding, and health authorities are challenged by the elevated prevalence ...
Roberto Bravo +8 more
doaj +1 more source
Mitochondrial dysfunction in white adipose tissue [PDF]
Trends in Endocrinology & Metabolism, 2012 Although mitochondria in brown adipose tissue and their role in non-shivering thermogenesis have been widely studied, we have only a limited understanding of the relevance of mitochondria in white adipose tissue (WAT) for cellular homeostasis of the adipocyte and their impact upon systemic energy homeostasis.
Christine M. Kusminski +1 more
openaire +3 more sources