Results 31 to 40 of about 3,494 (215)
Environment Conservation Journal, 2010 Ashwagandha [Withania somnifera (L.) Dunal] is an important medicinal plant and its medicinal properties have been attributed to various classes of withanolide compounds.
H. Punetha, Shiv Om Singh, A. K. Gaur
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Induction of Quinone Reductase by Withanolides
Journal of Natural Products, 2002 Thirty-seven naturally occurring withanolides (1-37), previously isolated in our laboratories, were evaluated for their potential to induce quinone reductase with cultured murine hepatoma cells (Hepa 1c1c7). Spiranoid (29, 32) and 18-functionalized withanolides (2-5, 7-9, 24) were found to be potent inducers of the enzyme, while 5alpha-substituted ...
Misico, Rosana Isabel +12 more
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RNAi and Homologous Over-Expression Based Functional Approaches Reveal Triterpenoid Synthase Gene-Cycloartenol Synthase Is Involved in Downstream Withanolide Biosynthesis in Withania somnifera. [PDF]
PLoS ONE, 2016 Withania somnifera Dunal, is one of the most commonly used medicinal plant in Ayurvedic and indigenous medicine traditionally owing to its therapeutic potential, because of major chemical constituents, withanolides.
Smrati Mishra +6 more
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Pharmacological Effects of Withanolides [PDF]
Biomedical Journal of Scientific & Technical Research, 2020 Withanolides is a class of active compounds widely found in Solanaceae plants. In traditional applications, it has a long history and a wide range of functions. With the progress of drug structure and pharmacological research, more and more reports point to its excellent anticancer effect.
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Withanolides from Withania coagulans
Phytochemistry, 2003 Two withanolides, 20beta-hydroxy-1-oxo-(22R)-witha-2,5,24-trienolide (1) and withacoagulin (2), along with a known withanolide, 17beta-hydroxy-14alpha, 20alpha-epoxy-1-oxo-(22R)-witha-3,5,24-trienolide (3) were isolated from Withania coagulans. Their structures were elucidated with the help of different spectroscopic techniques.
Atta, ur-Rahman +3 more
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Elucidating the active interaction mechanism of phytochemicals withanolide and withanoside derivatives with human serum albumin. [PDF]
PLoS ONE, 2018 Withania somnifera (Ashwagandha) is an efficient medicinal plant known in Ayurveda and Chinese medicine since ancient times, whose extracts are consumed orally as food supplement or as a health tonic owing to its several restorative properties for ...
Shreya Dubey +3 more
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De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis. [PDF]
PLoS ONE, 2013 Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides.
Parul Gupta +7 more
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Cells, 2022 Oxidative stress and the AKT serine/threonine kinase (AKT) signaling pathway are essential regulators in cellular migration, metastasis, and angiogenesis.
Jen-Yang Tang +6 more
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Withanolide-Type Steroids from Physalis nicandroides Inhibit HIV Transcription
, 2021 The aim of the present study is to report the isolation, structural elucidation, and antiviral evaluation of four new withanolide-type steroids, named nicansteroidins A-D (1-4), together with nine related known compounds (5-13) isolated from the aerial ...
Alcamí, José +8 more
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مجلة مركز بحوث التقنيات الاحيائيةBackground: Withania somnifera L. is a famous medicinal plant that has been utilized in Global folk medicine for a long time. The leaves and roots of the plant are rich in withanolide constituents, which are primarily responsible for their therapeutic ...
Ashwaq S. Abed +2 more
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