Results 41 to 50 of about 3,494 (215)

Effect of heavy metals on germination, biochemical, antioxidant and withanolide content in Withania somnifera (L.) Dunal [PDF]

, 2023
Withania somnifera (L.) Dunal., commonly referred to as Ashwagandha, is a medicinal plant from the solanaceae family with a wide range of pharmacological properties. W.
Akshatha Banadka, Praveen Nagella, Nagella, Praveen, Banadka, Akshatha   +3 more
core   +1 more source

In Silico Study on the Interactions, Molecular Docking, Dynamics and Simulation of Potential Compounds from Withania somnifera (L.) Dunal Root against Cancer by Targeting KAT6A

Molecules, 2023
Cancer is characterized by the abnormal development of cells that divide in an uncontrolled manner and further take over the body and destroy the normal cells of the body.
Sanjay H. Deshpande, Abdullatif Bin Muhsinah, Zabin K. Bagewadi, Gireesh M. Ankad, Mater H. Mahnashi, Deepak A. Yaraguppi, Ibrahim Ahmed Shaikh, Aejaz Abdullatif Khan, Harsha V. Hegde, Subarna Roy   +9 more
doaj   +1 more source

Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal

Frontiers in Plant Science, 2022
Ashwagandha (Withania somnifera L. Dunal) is a medicinally important plant with withanolides as its major bioactive compounds, abundant in the roots and leaves.
Sachin Ashok Thorat, Arya Kaniyassery, Poornima Poojari, Melissa Rangel, Shashikala Tantry, Kodsara Ramachandra Kiran, Manjunath B. Joshi, Padmalatha S. Rai, Anna-Maria Botha, Annamalai Muthusamy   +9 more
doaj   +1 more source

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

NADPH-cytochrome P450 reductase: molecular cloning and functional characterization of two paralogs from Withania somnifera (L.) dunal. [PDF]

PLoS ONE, 2013
Withania somnifera (L.) Dunal, a highly reputed medicinal plant, synthesizes a large array of steroidal lactone triterpenoids called withanolides. Although its chemical profile and pharmacological activities have been studied extensively during the last ...
Satiander Rana, Surrinder K Lattoo, Niha Dhar, Sumeer Razdan, Wajid Waheed Bhat, Rekha S Dhar, Ram Vishwakarma   +6 more
doaj   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source

Chemical structure of Withanolide A.

, 2014
Chemical structure of Withanolide A.
Thangavel Samikkannu (471645), Madhavan P. N. Nair (404586), Adriana Yndart (404585), Venkata Subba Rao Atluri (404582), Kesava Rao Venkata Kurapati (471644), Elena Kaftanovskaya (664371)   +5 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Chemical structures of the withanolide compounds.

, 2013
Chemical structures of the withanolide compounds.
Wen-Ying Chen (320786), Chin-Chung Wu (208863), Fang-Rong Chang (161357), Yi-Ling Tsai (320782), Yang-Chang Wu (4607), Hui-Chun Wang (208862), Mei-Hsin Liu (320785)   +6 more
core   +1 more source

Influence of Glomus intraradices on growth, biochemical changes and withanolides content of Withania somnifera L Dunal (Ashwagandha)

Environment Conservation Journal, 2013
Withania somnifera L. Dunal (Ashwagandha) also known as Indian ginseng, of the family Solanaceae is an important ancient medicinal plant, used in the Indian traditional system of medicine. The medicinal importance of W.
Neelima Ratti, Avinash Upadhyay
doaj   +1 more source