Results 91 to 100 of about 2,611 (169)

In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides

, 2012
Withania somnifera (L.) Dunal (Indian ginseng, winter cherry, Solanaceae) is widely used in traditional medicine. Roots are either chewed or used to prepare beverages (aqueous decocts).
Thomas Efferth, Henry Johannes Greten
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Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea

, 2019
Four new withanolides (2–5), together with 4β,7β,20-trihydroxy-1-oxowitha-2,5,24-trienolide (1), were isolated from the aerial parts of Eriolarynx iochromoides. The antiproliferative activity of all compounds purified from E.
Carina N. Casero, Sebastián J. Castro (5896067), Viviana E. Nicotra (1647790), Carina N. Casero (6684941), José M. Padrón (1478266), Viviana E. Nicotra, Sebastián J. Castro, José M. Padrón   +7 more
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Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

Molecules, 2009
Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years.
Javier Palazón, Rosa M. Cusido, Mercedes Bonfill, Elisabeth Moyano, Mohammad Hossein Mirjalili   +4 more
doaj   +1 more source

Withanolides array of Withania ashwagandha sp. novo populations from India

, 2014
Withania ashwagandha (Solanaceae) is an annual herb of immense medicinal value largely due to the presence of array of steroidal lactones called withanolides.
Koul, Sushma, Kumar, Arun, Khazir, Jabeena, Hakeem, Khalid Rehman, Mir, Bilal Ahmad   +4 more
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Metabolic Transformational Effects of Endosymbionts on Withanolides of Datura wrightii [PDF]

, 2015
Recent research has been published determining the presence of anticancerous withanolides in the plant Datura wrightii. These withanolides have been found to be antiproliferative towards cancers such as breast cancer, gliobastoma, and head and neck cell ...
Geary, Brad, Smart, Trevor
core  

Withametelin inhibits TGF-β induced Epithelial-to-Mesenchymal Transition and Programmed-Death Ligand-1 expression in vitro

Frontiers in Oncology
Withanolides are a group of naturally occurring plant-based small molecules known for their wide range of host cellular functions. The anticancer potential of withanolides has been explored in varying cancer cell lines in vitro.
Ashna Fathima, Mohammad Ali Farboodniay Jahromi, Sajeli A. Begum, Trinath Jamma   +3 more
doaj   +1 more source

Withanolides from Withania adpressa

, 2007
From the leaves of Withania adpressa, a plant endemic to Sahara of Morocco and Algeria, the novel steroidal lactone (22R)-14 alpha;,15 alpha;,17ß,20ß-tetrahydroxy-1-oxowitha-2,5,24-trien-26,22-olide (= (15S,17S)-14,15,17,20-tetrahydroxy-22,26 ...
Vitorge, Bruno, Christen, Philippe, Hostettmann, Kurt, Amzazi, Saaid, Benjouad, Abdelaziz, Jeannerat, Damien, Abdeljebbara, Lalla Hasna, Bekkoucheb, Khalid, Humam, Munir   +8 more
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Antiproliferative withanolides from the Solanaceae: A structure–activity study* [PDF]

, 2012
: As part of our search for bioactive compounds from plant biodiversity, 29 with-anolides were recently isolated from three members of the Solanaceae: Physalis longifolia, Vassobia breviflora, and Withania somnifera.
Abbas K. Samadi, Cohen, Mark S., Timmermann, Barbara N., Zhang, Huaping, Huaping Zhang, Mark S. Cohen, Samadi, Abbas K., Barbara N. Timmermann   +7 more
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Withanolides with Antibacterial Activity from Nicandra john-tyleriana

, 2016
Eleven new withanolides (1–11) were isolated and characterized from the aerial parts of Nicandra john-tyleriana. Five of these withanolides have an unmodified skeleton (1–5), two are acnistins (6, 7), and four are withajardins (8–11).
Fátima Gutiérrez Nicolás (1647781), Viviana E. Nicotra (1647790), Gloria E. Barboza (1647793), Guadalupe Reyes (1647787), María L. Uriburu (1647796), Segundo Leiva González (1647778), Marcela C. Audisio (1647784)   +6 more
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Liquid chromatography-mass spectrometry quantification of phytochemicals in Withania somnifera using data-dependent acquisition, multiple-reaction-monitoring, and parallel-reaction-monitoring with an inclusion list

Frontiers in Chemistry
Characterization of botanical extracts by mass spectrometry-based metabolomics analysis helps in determining the phytochemical composition that underlies their bioactivity and potential health benefits, while also supporting reproducibility of effects in
Luke C. Marney, Luke C. Marney, Jaewoo Choi, Jaewoo Choi, Armando Alcazar Magana, Armando Alcazar Magana, Armando Alcazar Magana, Liping Yang, Liping Yang, Natascha Techen, Natascha Techen, Md Nure Alam, Md Nure Alam, Mikah Brandes, Mikah Brandes, Amala Soumyanath, Amala Soumyanath, Jan F. Stevens, Jan F. Stevens, Jan F. Stevens, Claudia S. Maier, Claudia S. Maier, Claudia S. Maier   +22 more
doaj   +1 more source