Results 91 to 100 of about 2,412 (209)

Metabolites Identification of Bioactive Compounds Daturataturin A, Daturametelin I, N-Trans-Feruloyltyramine, and Cannabisin F From the Seeds of Datura metel in Rats

Frontiers in Pharmacology, 2018
Datura metel L. is a widely used traditional herbal medicine, and withanolides and amides are the two groups of main bioactive constituents in Datura metel seeds.
Silun Xu, Yan Liu, Ling Xiang, Fan Zhou, Hongyu Li, Yongjian Su, Xinyi Xu, Qi Wang   +7 more
doaj   +1 more source

Selective Antiproliferative Withanolides from Species in the Genera Eriolarynx and Deprea

, 2019
Four new withanolides (2–5), together with 4β,7β,20-trihydroxy-1-oxowitha-2,5,24-trienolide (1), were isolated from the aerial parts of Eriolarynx iochromoides. The antiproliferative activity of all compounds purified from E.
Carina N. Casero, Sebastián J. Castro (5896067), Viviana E. Nicotra (1647790), Carina N. Casero (6684941), José M. Padrón (1478266), Viviana E. Nicotra, Sebastián J. Castro, José M. Padrón   +7 more
core   +1 more source

Withanolides array of Withania ashwagandha sp. novo populations from India

, 2014
Withania ashwagandha (Solanaceae) is an annual herb of immense medicinal value largely due to the presence of array of steroidal lactones called withanolides.
Koul, Sushma, Kumar, Arun, Khazir, Jabeena, Hakeem, Khalid Rehman, Mir, Bilal Ahmad   +4 more
core   +1 more source

In Silico Analysis of Microarray-Based Gene Expression Profiles Predicts Tumor Cell Response to Withanolides

, 2012
Withania somnifera (L.) Dunal (Indian ginseng, winter cherry, Solanaceae) is widely used in traditional medicine. Roots are either chewed or used to prepare beverages (aqueous decocts).
Thomas Efferth, Henry Johannes Greten
core   +1 more source

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

Molecules, 2009
Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years.
Javier Palazón, Rosa M. Cusido, Mercedes Bonfill, Elisabeth Moyano, Mohammad Hossein Mirjalili   +4 more
doaj   +1 more source

Two new withanolides from the whole plants of Physalis peruviana

, 2022
Two new withaphysalin-type withanolides (18-O-ethylwithaphysalin R and 5-O-ethylphysaminimin C, 1 and 2), along with twelve known withanolides (3–14), were purified and identified from Physalis peruviana L.
Qian-Ran Li (13013962), Wei-Jie Zhang (1639576), Hui-Jun Liang (13013965), Jie Yuan (208425), Jie-Wei Wu (3914654), Bai-Lin Li (3914660), Xin Lian (3743395), Jia-Yan Chen (10588466), Zhuo-Yi Ao (13013968), Yu-Wen Fan (13013971), Juan-Juan Hu (7021394)   +10 more
core   +1 more source

Antiproliferative withanolides from the Solanaceae: A structure–activity study* [PDF]

, 2012
: As part of our search for bioactive compounds from plant biodiversity, 29 with-anolides were recently isolated from three members of the Solanaceae: Physalis longifolia, Vassobia breviflora, and Withania somnifera.
Abbas K. Samadi, Cohen, Mark S., Timmermann, Barbara N., Zhang, Huaping, Huaping Zhang, Mark S. Cohen, Samadi, Abbas K., Barbara N. Timmermann   +7 more
core   +1 more source

Withametelin inhibits TGF-β induced Epithelial-to-Mesenchymal Transition and Programmed-Death Ligand-1 expression in vitro

Frontiers in Oncology
Withanolides are a group of naturally occurring plant-based small molecules known for their wide range of host cellular functions. The anticancer potential of withanolides has been explored in varying cancer cell lines in vitro.
Ashna Fathima, Mohammad Ali Farboodniay Jahromi, Sajeli A. Begum, Trinath Jamma   +3 more
doaj   +1 more source

Withanolides with Antibacterial Activity from Nicandra john-tyleriana

, 2016
Eleven new withanolides (1–11) were isolated and characterized from the aerial parts of Nicandra john-tyleriana. Five of these withanolides have an unmodified skeleton (1–5), two are acnistins (6, 7), and four are withajardins (8–11).
Fátima Gutiérrez Nicolás (1647781), Viviana E. Nicotra (1647790), Gloria E. Barboza (1647793), Guadalupe Reyes (1647787), María L. Uriburu (1647796), Segundo Leiva González (1647778), Marcela C. Audisio (1647784)   +6 more
core   +1 more source

Physangulidines A, B, and C: Three New Antiproliferative Withanolides from Physalis angulata L.

, 2016
Bioassay-directed fractionation of the whole plant of Physalis angulata L. afforded three new antiproliferative withanolides with an unusual carbon framework: physangulidines A (1), B (2), and C (3).
Abraham J. Vaisberg (2108533), Nicole S. Stivers (2108539), Walter H. Lewis (2108536), Mark S. Mashuta (1596547), Neal J. Stolowich (2108542), Paula J. Bates (160809), Gerald B. Hammond (1325568), Zhuang Jin (263927)   +7 more
core   +2 more sources