Results 101 to 110 of about 2,611 (169)

Physangulidines A, B, and C: Three New Antiproliferative Withanolides from Physalis angulata L.

, 2016
Bioassay-directed fractionation of the whole plant of Physalis angulata L. afforded three new antiproliferative withanolides with an unusual carbon framework: physangulidines A (1), B (2), and C (3).
Abraham J. Vaisberg (2108533), Nicole S. Stivers (2108539), Walter H. Lewis (2108536), Mark S. Mashuta (1596547), Neal J. Stolowich (2108542), Paula J. Bates (160809), Gerald B. Hammond (1325568), Zhuang Jin (263927)   +7 more
core   +2 more sources

Cytotoxic Withanolides from Tubocapsicum anomalum

, 2007
Fifteen new withanolides (1−8, 11−17) and two known withanolides, withanolide D (9) and 17α-hydroxywithanolide D (10), were isolated from the stems, roots, and leaves of Tubocapsicum anomalum using bioassay-directed fractionation.
Wen-Chun Hung (303185), Jyun-Hong Chen (1466986), Shu-Li Chen (161389), Pei-Wen Hsieh (536545), Ching-Chung Wu (8660190), Ming-Hon Yen (2390002), Michael Y. Chiang (208860), Fang-Rong Chang (161357), Yu-Liang Yang (428617), Hsin-Fu Yen (2089069), Zih-You Huang (2101402), Yang-Chang Wu (4607), Tilo Lübken (8660193)   +12 more
core   +1 more source

Bioactive metabolites from the leaves of Withania adpressa

Pharmaceutical Biology, 2018
Context: Withania (Solanaceae) species are known to be a rich source of withanolides, which have shown several biological properties. Objective: To identify the compounds responsible for Withania adpressa Coss.
Widad Ben Bakrim, Laila El Bouzidi, Jean-Marc Nuzillard, Sylvian Cretton, Noémie Saraux, Aymeric Monteillier, Philippe Christen, Muriel Cuendet, Khalid Bekkouche   +8 more
doaj   +1 more source

Molecular Modelling of Withanolides Against EP2 Receptor for Treatment of Endometrial Cancer: A Pharmacokinetic and Molecular Docking Study

Chemistry Proceedings
Endometrial cancer is one of the most common gynecological cancers, with new global cases of approximately 420,000 new cases and 98,000 global deaths annually.
Grace Adaji, Asmau Nasir Hamza
doaj   +1 more source

Withanolides from Withania somnifera roots

, 2008
Two new and seven known withanolides along with β-sitosterol, stigmasterol, β-sitosterol glucoside, stigmasterol glucoside, α + β glucose were isolated from the roots of Withania somnifera.
Sangwan, Rajender S., Misra, Laxminarain, Pandey, Archana, Sangwan, Neelam S., Mishra, Priyanka, Tuli, Rakesh   +5 more
core   +1 more source

Withania somnifera (L.) Dunal, a Potential Source of Phytochemicals for Treating Neurodegenerative Diseases: A Systematic Review

Plants
Withania somnifera (L.) Dunal is a medicinal plant belonging to the traditional Indian medical system, showing various therapeutic effects such as anti-cancer, anti-inflammatory, anti-microbial, anti-diabetic, and hepatoprotective activity.
Valentina Lerose, Maria Ponticelli, Nadia Benedetto, Vittorio Carlucci, Ludovica Lela, Nikolay T. Tzvetkov, Luigi Milella   +6 more
doaj   +1 more source

Withanolides from Physalis angulata var. villosa and the Relative Configurational Revision of Some Known Analogs

Physalis angulata var. villosa is a plant possessing abundant withanolides, but in-depth research is lacking. In our ongoing study of P. angulata var.
Zhan-Peng Yu (17776715), Jian-Guang Luo (1344255), Jian-Fei Zhang (5048303), Ling Zhu (56356), Yu-Xing Cai (17776712), Ling-Yi Kong (1344264), Si-Fang Wu (17776709)   +6 more
core   +1 more source

Chitosan activates a sequential Ca ^<b>2+</b> -ROS-NO-jasmonate signaling cascade governing withanolide accumulation in <i>Withania somnifera</i>. [PDF]

Plant Signal Behav
Perveen S, Haider I, Mahmood A, Rehman SU, Nadeem MY, Zaheer A, Herqash RN, Noman OM, Alanzi AR.   +8 more
europepmc   +1 more source

Back to the Roots: Safety and Tolerability of Standardised Ashwagandha (<i>Withania somnifera</i>) Root Extract in Healthy Adults-A Systematic Review of Biomarkers and Adverse Events. [PDF]

Pharmaceuticals (Basel)
Coope OC, Willems MET, Levington A, Tallon MJ, Roman-Viñas B, Spurr TJ.   +5 more
europepmc   +1 more source

Effects of <i>Withania somnifera (L.) Dunal</i> (Ashwagandha) on cognitive and physical function in adults: a systematic review and meta-analysis. [PDF]

Front Pharmacol
Zhu X, Zeng Q, Lei Y, Xu D.
europepmc   +1 more source