Results 101 to 110 of about 2,412 (209)

Cytotoxic Withanolides from Tubocapsicum anomalum

, 2007
Fifteen new withanolides (1−8, 11−17) and two known withanolides, withanolide D (9) and 17α-hydroxywithanolide D (10), were isolated from the stems, roots, and leaves of Tubocapsicum anomalum using bioassay-directed fractionation.
Wen-Chun Hung (303185), Jyun-Hong Chen (1466986), Shu-Li Chen (161389), Pei-Wen Hsieh (536545), Ching-Chung Wu (8660190), Ming-Hon Yen (2390002), Michael Y. Chiang (208860), Fang-Rong Chang (161357), Yu-Liang Yang (428617), Hsin-Fu Yen (2089069), Zih-You Huang (2101402), Yang-Chang Wu (4607), Tilo Lübken (8660193)   +12 more
core   +1 more source

Liquid chromatography-mass spectrometry quantification of phytochemicals in Withania somnifera using data-dependent acquisition, multiple-reaction-monitoring, and parallel-reaction-monitoring with an inclusion list

Frontiers in Chemistry
Characterization of botanical extracts by mass spectrometry-based metabolomics analysis helps in determining the phytochemical composition that underlies their bioactivity and potential health benefits, while also supporting reproducibility of effects in
Luke C. Marney, Luke C. Marney, Jaewoo Choi, Jaewoo Choi, Armando Alcazar Magana, Armando Alcazar Magana, Armando Alcazar Magana, Liping Yang, Liping Yang, Natascha Techen, Natascha Techen, Md Nure Alam, Md Nure Alam, Mikah Brandes, Mikah Brandes, Amala Soumyanath, Amala Soumyanath, Jan F. Stevens, Jan F. Stevens, Jan F. Stevens, Claudia S. Maier, Claudia S. Maier, Claudia S. Maier   +22 more
doaj   +1 more source

Bioactive metabolites from the leaves of Withania adpressa

Pharmaceutical Biology, 2018
Context: Withania (Solanaceae) species are known to be a rich source of withanolides, which have shown several biological properties. Objective: To identify the compounds responsible for Withania adpressa Coss.
Widad Ben Bakrim, Laila El Bouzidi, Jean-Marc Nuzillard, Sylvian Cretton, Noémie Saraux, Aymeric Monteillier, Philippe Christen, Muriel Cuendet, Khalid Bekkouche   +8 more
doaj   +1 more source

Nutraceutical Applications of Withania somnifera: The Scientific Knowledge for Rational Modern Use of the “Ayurvedic Adaptogen”

Foods
Withania somnifera L. (Dunal), commonly known as Ashwagandha, is widely used in traditional medical systems, particularly Ayurveda, and is increasingly included in nutraceuticals and dietary supplements.
Sudip Pandey, Poonam Pant, Giovanni Corbioli, Erica Bonazzi, Miluska Cisneros-Yupanqui, Paola Salmaso, Stefano Dall’Acqua   +6 more
doaj   +1 more source

Molecular Modelling of Withanolides Against EP2 Receptor for Treatment of Endometrial Cancer: A Pharmacokinetic and Molecular Docking Study

Chemistry Proceedings
Endometrial cancer is one of the most common gynecological cancers, with new global cases of approximately 420,000 new cases and 98,000 global deaths annually.
Grace Adaji, Asmau Nasir Hamza
doaj   +1 more source

Withanolide glycosides from Physalis volubilis

Fitoterapia
The study of the acetone and methanol extracts of the stems, leaves, and flowers of Physalis volubilis led to obtain four withanolide glycosides (4, 6, 10, and 14). Compounds 1-3, 13, 15, and a sterol glycoside were also isolated. The structures were established by analysis of spectroscopic and spectrometric data, and by chemical transformations.
Ana-L, Pérez-Castorena, Tonantzin G, Anguheven L, M Azucena, Martínez R, Jesús, Morales-Jiménez, Emma, Maldonado, Mahinda, Martínez   +5 more
openaire   +2 more sources

Cytotoxic Withanolides From Acnistus Arborescens.

, 2015
Three cytotoxic withanolides, two with new structures, were isolated from the leaves of Acnistus arborescens and their structures determined by a combination of 1D and 2D NMR, mass spectral, and molecular modeling studies.
Cordell, Geoffrey A, Pezzuto, John M, Jonas, Patrick F, Minguzzi, Sandro, Shin, Young Geun, Chai, Hee Byung, Barata, Lauro E S, Park, Eun Jung   +7 more
core  

Metabolic Transformational Effects of Endosymbionts on Withanolides of Datura wrightii

, 2015
Recent research has been published determining the presence of anticancerous withanolides in the plant Datura wrightii. These withanolides have been found to be antiproliferative towards cancers such as breast cancer, gliobastoma, and head and neck cell ...
Geary, Brad, Smart, Trevor
core  

Antifeedant Activity Evaluation of Withanolides from Jaborosa integrifolia

, 2000
Antifeedant activity of the 4-deoxi-27-hydroxi-withanolides (1, 2 y 3) isolated from Jaborosa integrifolia (Solanaceae) was investigated in caterpillar Spodoptera littoralis on Leaf Disk Choice Bioassay.
Gloria M. Bonetto, Clarisa E. Vaccarini
core   +1 more source

Withania somnifera (L.) Dunal, a Potential Source of Phytochemicals for Treating Neurodegenerative Diseases: A Systematic Review

Plants
Withania somnifera (L.) Dunal is a medicinal plant belonging to the traditional Indian medical system, showing various therapeutic effects such as anti-cancer, anti-inflammatory, anti-microbial, anti-diabetic, and hepatoprotective activity.
Valentina Lerose, Maria Ponticelli, Nadia Benedetto, Vittorio Carlucci, Ludovica Lela, Nikolay T. Tzvetkov, Luigi Milella   +6 more
doaj   +1 more source