From herbal hope to hormonal havoc: chronic ashwagandha use and HPA axis suppression. [PDF]
Javid J, Kunnuru SR, Anne B, Muskan S.
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Unlocking the Power of Plant-Derived Natural Products: Therapeutic Benefits for Cognitive Health and Neuropsychiatric Symptoms in Dementia-Related Diseases. [PDF]
Koyama S +5 more
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HSCCC Straightforward Fast Preparative Method for Isolation of Two Major Cytotoxic Withanolides from Athenaea fasciculata (Vell.) I.M.C. Rodrigues & Stehmann. [PDF]
Marques AM, Brito LC, Figueiredo MR.
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Ashwagandha (<i>Withania somnifera</i>) Plant Extracts Affect the Cytochrome P450 System and Cytotoxicity of Primary Human Hepatocytes. [PDF]
McDonald KL +15 more
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Modulation of monoaminergic neurotransmission in substance use disorders: a neuropharmacological perspective focusing on plant-derived metabolites. [PDF]
Sivamaruthi BS +3 more
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Medicinal Plants and Their Bioactive Phytochemicals as Emerging Therapeutic Strategies for Alzheimer's Disease: An Integrative Review of Preclinical and Clinical Evidence. [PDF]
Siam NH +5 more
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Natural Bioactive Compounds Targeting FABP4 in Adipogenesis and Obesity: Evidence from In Vitro and In Vivo Studies. [PDF]
Sobczyński J +5 more
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Biosynthesis of the triterpenoid withanolides in Withania somnifera
Current Opinion in Plant BiologyAshwagandha (Withania somnifera L. Dunal) is a versatile medicinal plant of Solanaceae family, renowned for its potent therapeutic properties, due to which it is extensively used in Indian traditional systems of medicine such as Ayurveda. The medicinal properties are attributed to specialized metabolites known as withanolides, which are chemically ...
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Abstract The leaves of Datura metel yielded three new withanolides in addition to lycium substance B, previously reported from other Datura species. The structures of the withanolides, clarified by comprehensive spectral analysis, showed features of typical daturalactones as well as of the withanolides of D. metel. p -Hydroxy cinnamic acid amide
Anil B Ray
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