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Withanolides from Physalis coztomatl

Phytochemistry, 2015
Six withanolides (1-6), as well as two known withanolides (physachenolide D 7 and withanoside VI 8), were isolated from the aerial parts of Physalis coztomatl (Solanaceae). Structural elucidations of 1-6 were achieved through 2D NMR and other spectroscopic techniques, while the structure of 1 was confirmed by X-ray crystallographic analysis.
Zhang, Huaping   +5 more
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Biosynthesis of withanolides in Acnistus breviflorus: biogenetic relationships among the main withanolides

Phytochemistry, 1985
Abstract To excised leaves and 15-day-old seedlings of Acnistus breviflorus sodium [1- 14 C]acetate, [2- 14 C]mevalonolactone and [ 14 C-methyl]methionine were administered in separate experiments. From the absolute incorporation values of withaferin A (1), jaborosalactone A (2) and jaborosalactone D (3) isolated at different times after ...
Adriana S. Veleiro   +2 more
openaire   +1 more source

Withanolides of Acnistus breviflorus

Phytochemistry, 1981
The chemical examination of Acnistus breviflorus afforded nine withanolides, four of which are new and were established as 2,3,24,25-tetrahydro-27-desoxywithaferin A (4β-hydroxy-5β,6β-epoxy-1-oxo-22 R-withanolide), 2,3-dihydro-27-desoxywithaferin A (4β-hydroxy-5β,6β-epoxy-22 R-witha-24-enolide), 5,6-desoxywithaferin A (4β,27-dihydroxy-1-oxo-22 R-witha ...
S. Sarma Nittala, David Lavie
openaire   +1 more source

New withanolides from Mandragora officinarum: First report of withanolides from the Genus Mandragora

Fitoterapia, 2010
Two new withanolides named mandragorolide A (1) and mandragorolide B (2) were isolated from the MeOH extract of the whole plant of Mandragora officinarum of Jordanian origin, along with five known withanolides namely larnaxolide A (3), withanolide B (4), datura lactone 2 (5), withanicandrin (6) and salpichrolide C (7). Compound 3 has been reported only
Rami K, Suleiman   +2 more
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Withanolides from Physalis hispida

Journal of Natural Products, 2014
Nine new withanolides (1-9), withahisolides A-I, were isolated along with nine known compounds (10-18) from the aerial parts of Physalis hispida. The structures of 1-9 were elucidated through a variety of spectroscopic techniques, while the structures of 1 and 2 were confirmed by X-ray crystallographic analysis. Compounds 1-3 are the first withanolides
Cong-Mei, Cao   +7 more
openaire   +2 more sources

Antiproliferative Withanolides from Jaborosa Riojana

Fitoterapia
Six previously undescribed withanolides, of which three had a normal glycosylated skeleton (Jaborosalactones 49-51) and three had a sativolide skeleton (12-O-methyl jaborosalactone 52, jaborosalactone 53, and 12-O-methyl jaborosalactone 53), were isolated from the aerial parts of Jaborosa riojana.
Lobatto, Virginia Laura   +4 more
openaire   +3 more sources

Withanolides from Ajuga parviflora

Journal of Natural Products, 1999
Two new withanolides named ajugin A [14alpha,20, 28-trihydroxy-1-oxo-(20R,22R)-witha-3,5,24-trienolide] (1) and ajugin B [14alpha,20,27-trihydroxy-1-oxo-(20R,22R)-witha-5, 24-dienolide] (2) were isolated from the whole plant of Ajuga parviflora, and their structures were deduced by NMR and MS analyses.
, Khan, , Malik, , Ahmad, , Nawaz
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Cytotoxic withanolides from Acnistus arborescens

Phytochemistry, 2002
Three cytotoxic withanolides, two with new structures, were isolated from the leaves of Acnistus arborescens and their structures determined by a combination of 1D and 2D NMR, mass spectral, and molecular modeling studies. Dereplication analysis of the ethyl ether extract was useful for evaluating the components showing significant cytotoxic activity.
Sandro, Minguzzi   +7 more
openaire   +2 more sources

Withanolides from Withania adpressa

Helvetica Chimica Acta, 2007
AbstractFrom the leaves of Withania adpressa, a plant endemic to Sahara of Morocco and Algeria, the novel steroidal lactone (22R)‐14α,15α,17β,20β‐tetrahydroxy‐1‐oxowitha‐2,5,24‐trien‐26,22‐olide (= (15S,17S)‐14,15,17,20‐tetrahydroxy‐22,26‐epoxyergosta‐2,5,24‐triene‐1,26‐dione; 1), was isolated, along with three known compounds, withanolides F (2), J (3)
Abdeljebbara, Lalla Hasna   +8 more
openaire   +2 more sources

Withanolides from Withania somnifera roots

Phytochemistry, 2008
Two new and seven known withanolides along with beta-sitosterol, stigmasterol, beta-sitosterol glucoside, stigmasterol glucoside, alpha+beta glucose were isolated from the roots of Withania somnifera. Among the known compounds, Viscosa lactone B, stigmasterol, stigmasterol glucoside and alpha+beta glucose are being reported from the roots of W ...
Laxminarain, Misra   +5 more
openaire   +2 more sources

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