Results 81 to 90 of about 2,412 (209)

Parameters affecting microwave-assisted extraction of withanolides

open access: yes, 2001
Focused microwave-assisted extraction was applied to the extraction of three main withanolides from airdried leaves of Iochroma gesnerioides, namely, withaferin A, iochromolide and withacnistin. Six extraction variables, i.e.
Christen, Philippe   +2 more
core   +1 more source

The Effect of Colchicine on Profiles and Contents of Withanolides of Ciplukan (Physalis angulata) In vitro

open access: yes, 2022
This study aimed to determine the effect of in vitro polyploid induction using colchicine on the content of withanolides in Physalis angulata shoots.
Mastuti, Retno   +2 more
core   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima   +15 more
wiley   +1 more source

Natural Dietary Compounds Targeting NF‐κB Signaling in Cancer: Implications for Nutrition‐Based Prevention and Therapy

open access: yesFood Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT Dysregulation of the nuclear factor kappa B (NF‐κB) signaling pathway is closely associated with inflammation‐driven carcinogenesis, tumor progression and resistance to conventional therapies. Sustained NF‐κB activation enhances malignant cell survival, proliferation and immune evasion by promoting proinflammatory and antiapoptotic gene ...
Maria Sharif   +10 more
wiley   +1 more source

Biological Activity of Withanolides

open access: yes, 2000
904-911A large number of withanolides are isolated from solanaceous plants and some derivatives are also prepared. Some of the withanolides, mainly Withaferin A(WA),Withanolide D(WD), Withanolide E(WE), 3β- hydroxy-2,3-dihydrowithanolide F, and ...
Budhiraja, R D   +2 more
core  

Effect of Ashwagandha Withanolides on Muscle Cell Differentiation

open access: yes, 2021
Withania somnifera (Ashwagandha) is used in Indian traditional medicine, Ayurveda, and is believed to have a variety of health-promoting effects. The molecular mechanisms and pathways underlying these effects have not yet been sufficiently explored.
Renu Wadhwa   +6 more
core   +1 more source

Callus induction and withanolides production through cell suspension culture of Withania coagulans (Stocks) Dunal

open access: yesJournal of Medicinal Plants, 2022
Background: Withania coagulans (Stocks) Dunal is a well-known medicinal plant due to its many healing properties. Objective: The aim of the present study was to induce friable callus and subsequently establish the plant cell suspension cultures for the ...
Mohammad Hossein Mirjalili   +1 more
doaj  

Antiproliferative Withanolides from Datura wrightii

open access: yes, 2016
A new withanolide, named withawrightolide (1), and four known withanolides (2–5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques.
Robert J. Gallagher (1828222)   +8 more
core   +1 more source

Toxicological Assessment of LN20188, a Botanical Combination of Withania somnifera Root and Abelmoschus esculentus Fruit Extracts

open access: yesBioMed Research International, Volume 2026, Issue 1, 2026.
LN20188 is a botanical combination composed of extracts derived from Withania somnifera (L.) Dunal root and Abelmoschus esculentus (L.) Moench fruit. Our earlier investigations revealed the benefits of LN20188 in promoting gut motility and reducing constipation.
Ravikumar Madireddy   +4 more
wiley   +1 more source

Natural Withanolides in the Treatment of Chronic Diseases [PDF]

open access: yes, 2016
Withanolides, and in particular extracts from Withania somnifera, have been used for over 3,000 years in traditional Ayurvedic and Unani Indian medical systems as well as within several other Asian countries. Traditionally, the extracts were ascribed a wide range of pharmacologic properties with corresponding medical uses, including adaptogenic ...
White, Peter T.   +3 more
openaire   +2 more sources

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