Results 81 to 90 of about 2,412 (209)
Parameters affecting microwave-assisted extraction of withanolides
Focused microwave-assisted extraction was applied to the extraction of three main withanolides from airdried leaves of Iochroma gesnerioides, namely, withaferin A, iochromolide and withacnistin. Six extraction variables, i.e.
Christen, Philippe +2 more
core +1 more source
This study aimed to determine the effect of in vitro polyploid induction using colchicine on the content of withanolides in Physalis angulata shoots.
Mastuti, Retno +2 more
core +1 more source
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
ABSTRACT Dysregulation of the nuclear factor kappa B (NF‐κB) signaling pathway is closely associated with inflammation‐driven carcinogenesis, tumor progression and resistance to conventional therapies. Sustained NF‐κB activation enhances malignant cell survival, proliferation and immune evasion by promoting proinflammatory and antiapoptotic gene ...
Maria Sharif +10 more
wiley +1 more source
Biological Activity of Withanolides
904-911A large number of withanolides are isolated from solanaceous plants and some derivatives are also prepared. Some of the withanolides, mainly Withaferin A(WA),Withanolide D(WD), Withanolide E(WE), 3β- hydroxy-2,3-dihydrowithanolide F, and ...
Budhiraja, R D +2 more
core
Effect of Ashwagandha Withanolides on Muscle Cell Differentiation
Withania somnifera (Ashwagandha) is used in Indian traditional medicine, Ayurveda, and is believed to have a variety of health-promoting effects. The molecular mechanisms and pathways underlying these effects have not yet been sufficiently explored.
Renu Wadhwa +6 more
core +1 more source
Background: Withania coagulans (Stocks) Dunal is a well-known medicinal plant due to its many healing properties. Objective: The aim of the present study was to induce friable callus and subsequently establish the plant cell suspension cultures for the ...
Mohammad Hossein Mirjalili +1 more
doaj
Antiproliferative Withanolides from Datura wrightii
A new withanolide, named withawrightolide (1), and four known withanolides (2–5) were isolated from the aerial parts of Datura wrightii. The structure of compound 1 was elucidated through 2D NMR and other spectroscopic techniques.
Robert J. Gallagher (1828222) +8 more
core +1 more source
LN20188 is a botanical combination composed of extracts derived from Withania somnifera (L.) Dunal root and Abelmoschus esculentus (L.) Moench fruit. Our earlier investigations revealed the benefits of LN20188 in promoting gut motility and reducing constipation.
Ravikumar Madireddy +4 more
wiley +1 more source
Natural Withanolides in the Treatment of Chronic Diseases [PDF]
Withanolides, and in particular extracts from Withania somnifera, have been used for over 3,000 years in traditional Ayurvedic and Unani Indian medical systems as well as within several other Asian countries. Traditionally, the extracts were ascribed a wide range of pharmacologic properties with corresponding medical uses, including adaptogenic ...
White, Peter T. +3 more
openaire +2 more sources

