Results 1 to 10 of about 459,861 (330)

Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis [PDF]

Cells, 2019
Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Yu Ji, Hongyan Hao, Kurt Reynolds, Moira McMahon, Chengji J. Zhou   +4 more
doaj   +4 more sources

Physical Activity as a Preventive Lifestyle Intervention Acts Through Specific Exosomal miRNA Species—Evidence From Human Short- and Long-Term Pilot Studies

Frontiers in Physiology, 2021
Exercise initiates systemic adaptation to promote health and prevent various lifestyle-related chronic diseases. Emerging evidence suggests that circulating exosomes mediate some of the beneficial effects of exercise via the transfer of microRNAs between
Kitti Garai, Kitti Garai, Zoltan Adam, Zoltan Adam, Robert Herczeg, Krisztina Banfai, Krisztina Banfai, Adam Gyebrovszki, Attila Gyenesei, Judit E. Pongracz, Judit E. Pongracz, Marta Wilhelm, Krisztian Kvell, Krisztian Kvell   +13 more
doaj   +1 more source

Sustained expression of unc-4 homeobox gene and unc-37/Groucho in postmitotic neurons specifies the spatial organization of the cholinergic synapses in C. elegans

eLife, 2021
Neuronal cell fate determinants establish the identities of neurons by controlling gene expression to regulate neuronal morphology and synaptic connectivity.
Mizuki Kurashina, Jane Wang, Jeffrey Lin, Kathy Kyungeun Lee, Arpun Johal, Kota Mizumoto   +5 more
doaj   +1 more source

Crosstalk Between ER Stress, Unfolded Protein Response (UPR) and Wnt Signaling Pathway in Cancer [PDF]

Iranian Journal of Colorectal Research, 2020
: 1. Context Endoplasmic reticulum stress (ER stess) is associated with endoplasmic reticulum perturbation homeostasis. Prolonged ER stress conditions may induce cell death. Unfolded protein response (UPR) attempts to restore normal cell conditions.
Morvarid Siri, Seyed Vahid Hosseini, Sanaz Dastghaib, Pooneh Mokarram   +3 more
doaj   +1 more source

The amyloid precursor protein is a conserved Wnt receptor

eLife, 2021
The Amyloid Precursor Protein (APP) and its homologues are transmembrane proteins required for various aspects of neuronal development and activity, whose molecular function is unknown.
Tengyuan Liu, Tingting Zhang, Maya Nicolas, Lydie Boussicault, Heather Rice, Alessia Soldano, Annelies Claeys, Iveta Petrova, Lee Fradkin, Bart De Strooper, Marie-Claude Potier, Bassem A Hassan   +11 more
doaj   +1 more source

Rab7 is required for mesoderm patterning and gastrulation in Xenopus

Biology Open, 2021
Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis, Fee M. Wielath, Philipp Vick   +2 more
doaj   +1 more source

Circular RNAs

EXCLI Journal : Experimental and Clinical Sciences, 2023
Circular RNAs (CircRNAs) are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. CircRNA dysregulation has been shown to disrupt the interaction of the Wnt/β-catenin pathway, which regulates several biological processes
Mina Alimohammadi, Yasaman Gholinezhad, Vahide Mousavi, Samaneh Kahkesh, Malihe Rezaee, Alireza Yaghoobi, Alireza Mafi, Mahmood Araghi   +7 more
doaj   +1 more source

SLC20a1/PiT-1 is required for chorioallantoic placental morphogenesis

Vascular Biology, 2023
The placenta mediates the transport of nutrients, such as inorganic phosphate (Pi), between the maternal and fetal circulatory systems. The placenta itself also requires high levels of nutrient uptake as it develops to provide critical support for fetal ...
Ana Correia-Branco, Ariel Mei, Sreehari Pillai, Nirmala Jayaraman, Radhika Sharma, Alison G Paquette, Naveen K Neradugomma, Ciara Benson, Nicholas W Chavkin, Qingcheng Mao, Mary C Wallingford   +10 more
doaj   +1 more source

Quantitative analysis of signaling responses during mouse primordial germ cell specification

Biology Open, 2021
During early mammalian development, the pluripotent cells of the embryo are exposed to a combination of signals that drive exit from pluripotency and germ layer differentiation.
Sophie M. Morgani, Anna-Katerina Hadjantonakis   +1 more
doaj   +1 more source

Upregulated wnt-11 and mir-21 expression trigger epithelial mesenchymal transition in aggressive prostate cancer cells [PDF]

, 2020
Prostate cancer (PCa) is the second-leading cause of cancer-related death among men. microRNAs have been identified as having potential roles in tumorigenesis.
Arisan, E.D., Arisan, E.D., Freitas, I.L., Freitas, I.L., Keskin, B., Keskin, B., Kothari, A., Kothari, A., Radzali, S., Radzali, S., Rencuzogullari, O., Rencuzogullari, O., Uysal-Onganer, P., Uysal-Onganer, P., Warford, A., Warford, A.   +15 more
core   +1 more source