Results 21 to 30 of about 315,126 (245)
To Wnt or not to Wnt: the bone and joint health dilemma [PDF]
Nature Reviews Rheumatology, 2013 The Wnt signalling cascades have essential roles in development, growth and homeostasis of joints and the skeleton. Progress in basic research, particularly relating to our understanding of intracellular signalling cascades and fine regulation of receptor activation in the extracellular space, has provided novel insights into the roles of Wnt ...
Maripat Corr, Nancy E Lane, Rik Lories
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Wnt your brain be inflamed? Yes, it Wnt! [PDF]
Trends in Molecular Medicine, 2013 The roles of Wnts in neural development, synaptogenesis, and cancer are generally well characterized. Nonetheless, evidence exists that interactions between the immune and nervous systems control major brain regenerative processes ranging from physiological or pathological (reparative) regeneration to neurogenesis and synaptic plasticity.
MARCHETTI, Bianca Maria, Pluchino S.
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Cartilage development and degeneration: a Wnt Wnt situation [PDF]
Cell Biochemistry and Function, 2012 The Wnt signaling pathway plays a crucial role in the development and homeostasis of a variety of adult tissues and, as such, is emerging as an important therapeutic target for numerous diseases. Factors involved in the Wnt pathway are expressed throughout limb development and chondrogenesis and have been shown to be critical in joint homeostasis and ...
Colin Farquharson +2 more
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Frontiers in Physiology, 2019 Studies support that regular physical activity (PA) decelerates senescence-related decline of physiological and molecular parameters in the elderly. We have addressed the other end of this spectrum: healthy and young, inactive individuals participated in
Kitti Garai +15 more
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Bionanotechnological strategies for the synthesis of quercetin conjugates with selenium nanoparticles for their targeting of the Wnt/Ca2+signaling pathway [PDF]
Технологія виробництва і переробки продуктів тваринництва, 2023 One of the applications of nanotechnology is the synthesis of nanoparticles for targeted drug delivery and disease prevention. In the agricultural sector, nanotechnology holds great promise for improving animal health and productivity.
Bityutskyy V.S. +5 more
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eLife, 2022 Precise synaptic connection of neurons with their targets is essential for the proper functioning of the nervous system. A plethora of signaling pathways act in concert to mediate the precise spatial arrangement of synaptic connections.
Ardalan Hendi +5 more
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Developmental Cell, 2003 AbstractA recent Juan March Foundation workshop on “wnt genes and Wnt signaling” brought developmental and cancer biologists together to share some of the latest advances in Wnt research. Discussion topics included molecular, genetic, and genomic dissections of wnt genes in embryogenesis and cancer, Wnt signaling components and downstream targets ...
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miR-7 Controls the Dopaminergic/Oligodendroglial Fate through Wnt/β-catenin Signaling Regulation
Cells, 2020 During the development of the central nervous system, the proliferation of neural progenitors and differentiation of neurons and glia are tightly regulated by different transcription factors and signaling cascades, such as the Wnt and Shh pathways.
Lavanya Adusumilli +12 more
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Biology Open, 2021 Wnt signalling is a core pathway involved in a wide range of developmental processes throughout the metazoa. In vitro studies have suggested that the small GTP binding protein Arf6 regulates upstream steps of Wnt transduction, by promoting the ...
Julien Marcetteau +3 more
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The Wnt signaling pathway in development and disease.
Annual Review of Cell and Developmental Biology, 2004 Tight control of cell-cell communication is essential for the generation of a normally patterned embryo. A critical mediator of key cell-cell signaling events during embryogenesis is the highly conserved Wnt family of secreted proteins.
C. Logan, R. Nusse
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