Results 41 to 50 of about 315,126 (245)
Cell Stem Cell, 2008 The molecular signals that regulate the regenerative function of satellite cells in the skeletal muscle remain largely obscure. In this issue of Cell Stem Cell, Brack et al. (2008) report that direct molecular crosstalk between stem cell self-renewal and differentiation pathways determines the timing and efficiency of muscle repair.
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eLife, 2016 Many organisms lose the capacity to regenerate damaged tissues as they mature. Damaged Drosophila imaginal discs regenerate efficiently early in the third larval instar (L3) but progressively lose this ability.
Robin E Harris +3 more
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Wnt/β-catenin signaling in the adrenal glands of rats in various types of experimental hypertension
Endocrine Connections, 2022 Wnt/β-catenin signaling plays a key role in maintaining homeostasis, which is disturbed in hypertension. Taking into account the lack of literature describing changes in the Wnt/β-catenin pathway in the adrenal glands under conditions of elevated ...
Irena Kasacka +3 more
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eLife, 2016 How cells in the embryo coordinate epithelial plasticity with cell fate decision in a fast changing cellular environment is largely unknown. In chick embryos, skeletal muscle formation is initiated by migrating Delta1-expressing neural crest cells that ...
Daniel Sieiro +3 more
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WNT Signaling in Disease [PDF]
Cells, 2019 Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans.
Li Ng +7 more
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Hematopoietic stem cells, overview and pathways implied on their self-renewal mechanisms [PDF]
Revista Ciencias de la Salud, 2007 Blood tissue is composed approximately in45% by cells and its derivatives, with a life spanof around 120 days for erythrocytes and 3 yearsfor certain type of lymphocytes.
Sandra Ramírez Clavijo +2 more
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β-Catenin inhibition shapes tumor immunity and synergizes with immunotherapy in colorectal cancer
OncoImmunology, 2020 In colorectal cancer, Wnt/β-catenin signaling is often aberrantly activated and associated with a T-cell-excluded phenotype which is a major obstacle for many immunotherapies.
Caihong Wang +6 more
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Wnt Signaling in the Niche [PDF]
Cell, 2008 There is much interest in understanding the signals in the bone marrow niche that keep hematopoietic stem cells (HSCs) in a quiescent state. In the current issue of Cell Stem Cell, Fleming et al. (2008) report that blocking Wnt signaling in the niche increases the number of proliferating HSCs and reduces their ability to reconstitute the hematopoietic ...
Toshio Suda, Fumio Arai
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Exosomal Dvl3 promoted the aggressive phenotypic transformation of RA-FLS via wnt pathway
Autoimmunity, 2022 Objective This study was performed to explore the function and mechanism of Dvl3 in RA-FLS by exosome intervention. Methods The expression pattern of Dvl3 was examined by IHC, WB, and qPCR.
Weixing Tan +8 more
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WormBook, 2005 The use of Wnt ligands for signaling between cells is a conserved feature of metazoan development. Activation of Wnt signal transduction pathways upon ligand binding can regulate diverse processes including cell proliferation, migration, polarity, differentiation and axon outgrowth.
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