Results 61 to 70 of about 5,645,262 (348)
β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation. [PDF]
PLoS ONE, 2014 β-Catenin independent, non-canonical Wnt signaling pathways play a major role in the regulation of morphogenetic movements in vertebrates. The term non-canonical Wnt signaling comprises multiple, intracellularly divergent, Wnt-activated and β-Catenin ...
Katharina Seitz +5 more
doaj +1 more source
Autophagy and the Wnt Signaling Pathway: A Focus on Wnt/β-catenin signaling.
Biochimica et biophysica acta. Molecular cell research, 2020 Cellular homeostasis and adaptation to various environmental conditions are importantly regulated by the sophisticated mechanism of autophagy and its crosstalk with Wnt signaling and other developmental pathways.
Shahrokh Lorzadeh +3 more
semanticscholar +1 more source
Wnt Signaling in Mitosis [PDF]
Developmental Cell, 2009 Previously, the connection between cell proliferation and Wnt signaling focused on transcriptional activation of cyclin D1 and c-myc, which control the G1/S transition of the cell cycle. In this issue of Developmental Cell, the Niehrs group demonstrates mitotic activation of Wnt signaling by a novel Cdk/cyclin complex containing Cdk14 (PFTK1) and ...
Kaldis, Philipp, Pagano, Michele
openaire +2 more sources
Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review
, 2021 The wound healing that follows myocardial infarction is a complex process involving multiple mechanisms, such as inflammation, angiogenesis and fibrosis.
Daskalopoulos, Evangelos-Panagiotis +5 more
core +1 more source
Wnt signaling: a common theme in animal development.
Genes & Development, 1997 Wnt proteins are now recognized as one of the major families of developmentally important signaling molecules, with mutations in Wnt genes displaying remarkable phenotypes in the mouse, Caenorhabditis elegans, and Drosophila.
K. Cadigan, R. Nusse
semanticscholar +1 more source
Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer
Cell Death and Differentiation, 2022 The development of chemotherapy resistance is the most vital obstacle to clinical efficacy in gastric cancer (GC). The dysregulation of the Wnt/beta-catenin signaling pathway is critically associated with GC development and chemotherapy resistance ...
Yue Wang +14 more
semanticscholar +1 more source
Rethinking WNT signalling [PDF]
Nature, 2018 The identification of genetic mutations that can hinder the development of human limbs has led to the discovery of an unanticipated mode of regulation for the WNT signalling pathway during limb development. The identification of genetic mutations that can hinder the development of human limbs has led to the discovery of an unanticipated mode of ...
Jessica A, Lehoczky, Clifford J, Tabin
openaire +2 more sources
Cell Reports, 2018 Summary: Wnt/β-catenin signaling is necessary for lymphatic vascular development. Oscillatory shear stress (OSS) enhances Wnt/β-catenin signaling in cultured lymphatic endothelial cells (LECs) to induce expression of the lymphedema-associated ...
Boksik Cha +16 more
doaj +1 more source
Wnt/β-catenin signaling pathway in carcinogenesis and cancer therapy
Journal of Hematology & OncologyThe Wnt/β-catenin signaling pathway plays a crucial role in various physiological processes, encompassing development, tissue homeostasis, and cell proliferation.
Pan Song +7 more
semanticscholar +1 more source
, 2012 Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Devraj, Kavi +29 more
core +1 more source