Zhongguo gonggong weisheng, 2023 Objective To conduct whole genome sequencing of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) Omicron variant strains isolated from patients of a coronavirus disease 2019 (COVID-19) epidemic in Shandong province for effective control of COVID-
Zan-zan LIU, Cui-hua XIE, Ya-juan JIANG
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WWTR1 (WW domain containing transcription regulator 1) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2014 WWTR1 (also called TAZ in publications. Therefore, TAZ is used in the following description) is a WW domaing-containing transcriptional coactivator, which was first identified as a 14-3-3 binding protein. TAZ is the downstream component in the Hippo pathway, and also has been found to interact with different pathways, such as Wnt, TGFbeta, etc.
Zhao, Y, Yang, X
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Functions of WW domains in the nucleus [PDF]
FEBS Letters, 2001 The WW domain is a protein module found in a wide range of signaling proteins. It is one of the smallest protein modules that folds as a monomer without disulfide bridges or cofactors. WW domains bind proteins containing short linear peptide motifs that are proline‐rich or contain at least one proline. Although the WW domain was initially considered a ‘
Sudol, Marius +2 more
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WW Scattering Parameters via Pseudoscalar Phase Shifts [PDF]
, 2012 Using domain-wall lattice simulations, we study pseudoscalar-pseudoscalar scattering in the maximal isospin channel for an SU(3) gauge theory with two and six fermion flavors in the fundamental representation.
Appelquist, Thomas +17 more
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WW domain-binding protein 2: an adaptor protein closely linked to the development of breast cancer
Molecular Cancer, 2017 The WW domain is composed of 38 to 40 semi-conserved amino acids shared with structural, regulatory, and signaling proteins. WW domain-binding protein 2 (WBP2), as a binding partner of WW domain protein, interacts with several WW-domain-containing ...
Shuai Chen +10 more
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Recognition mechanism of p63 by the E3 ligase Itch Novel strategy in the study and inhibition of this interaction. [PDF]
, 2012 The HECT-containing E3 ubiquitin ligase Itch mediates the degradation of several proteins, including p63 and p73, involved in cell specification and fate.
Barbato, G +4 more
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Functional complexes between YAP2 and ZO-2 are PDZ domain-dependent, and regulate YAP2 nuclear localization and signalling [PDF]
, 2010 he Hippo pathway regulates the size of organs by controlling two opposing processes: proliferation and apoptosis. YAP2 (Yes kinase-associated protein 2), one of the three isoforms of YAP, is a WW domain-containing transcriptional co-activator that acts ...
Bader, Gary D +10 more
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A modified Oster-Murray-Harris mechanical model of morphogenesis [PDF]
, 2013 There are two main modeling paradigms for biological pattern formation in developmental biology: chemical prepattern models and cell aggregation models. This paper focuses on an example of a cell aggregation model, the mechanical model developed by Oster,
Benjamin L. Vaughan +6 more
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Functional characterisation of the WW minimal domain for delivering therapeutic proteins by adenovirus dodecahedron. [PDF]
PLoS ONE, 2012 Protein transduction offers a great therapeutic potential by efficient delivery of biologically active cargo into cells. The Adenovirus Dd (Dodecahedron) has recently been shown to deliver proteins fused to the tandem WW(2-3-4) structural domains from ...
Ana Villegas-Méndez +6 more
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Molecular Interactions between Two LMP2A PY Motifs of EBV and WW Domains of E3 Ubiquitin Ligase AIP4
Life, 2021 Interactions involving Epstein–Barr virus (EBV) LMP2A and Nedd4 family E3 ubiquitin–protein ligases promote the ubiquitination of LMP2A-associated proteins, which results in the perturbation of normal B-cell signaling.
Min-Duk Seo +5 more
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