Preparative Electrochemical Reduction of 2-Amino-6-chloropurine and Synthesis of 6-Deoxyacyclovir, a Fluorescent Substrate of Xanthine Oxidase and a Prodrug of Acyclovir. [PDF]
, 1987 J. T. Kuśmierek +4 more
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Antibiotic‐mediated immune modulation in periodontitis
Periodontology 2000, EarlyView.Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez +6 more
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Polytypes and planar defects revealed in the purine base xanthine using multi-dimensional electron diffraction. [PDF]
Commun ChemLeung HW +6 more
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Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease
Experimental Physiology, EarlyView.Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi +4 more
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Unveiling of phosphodiesterase-5 hot residues binding to xanthine derivatives for erectile dysfunction therapy: A computational drug repurposing approach. [PDF]
PLoS OneElzupir AO, Almahmoud SAJ.
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Effect of N-ethylmaleimide on the activities of xanthine oxidase and dehydrogenase in rabbit liver
, 1999 Yohko Fujimoto +3 more
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Experimental Physiology, EarlyView.Abstract This study aimed to determine whether sodium nitrite supplementation prevented chronic stress‐induced cerebrovascular dysfunction and cognitive decline. We hypothesize that nitrite supplementation will prevent the oxidative environment and cerebrovascular dysfunction associated with chronic stress and maintain cognitive health.
Emily Burrage +10 more
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Evaluation of silica nanoparticles coated by imprinted polymer for enzymatic determination of hypoxanthine using ferroin as freshness sensor in fish samples. [PDF]
Sci RepHashemi-Moghaddam H, Soylak M.
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir +5 more
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