Results 191 to 200 of about 112,529 (303)

Torreya grandis Seed Polyphenols Protect RAW264.7 Macrophages by Inhibiting Oxidative Stress and Inflammation

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Torreya grandis seed polyphenols (TGSP), primarily containing gallic acid and epicatechin, exhibit selective free radical scavenging activity. TGSP pretreatment effectively inhibits LPS‐induced inflammatory responses by reducing TNF‐α, NO, and IL‐6 production. TGSP also alleviates H2O2‐induced oxidative stress by enhancing antioxidant enzyme activities
Ran Liu   +7 more
wiley   +1 more source

Phenolic Compounds in Exercise Physiology: Dual Role in Oxidative Stress and Recovery Adaptation

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Exercise increases mitochondrial activity and reactive oxygen species (ROS) production, which can lead to oxidative stress. However, phenolic compounds act as potent antioxidants, counteracting ROS and thereby mitigating oxidative stress. This graphical abstract illustrates the dual role of exercise and dietary antioxidants in the regulation of redox ...
Kübra Özdemir, Yeliz Demir
wiley   +1 more source

Deep Supramolecular Language Processing for Co‐Crystal Prediction

open access: yesAngewandte Chemie, Volume 137, Issue 29, July 14, 2025.
DeepCocrystal is a deep learning model that predicts co‐crystal formation by learning supramolecular interactions from molecular string representations. It achieves high accuracy, estimates uncertainty, and offers interpretable insights into its predictions. Validated prospectively, DeepCocrystal discovered novel diflunisal co‐crystals and is available
Rebecca Birolo   +5 more
wiley   +2 more sources

Osteoarthritis: Mechanisms and Therapeutic Advances

open access: yesMedComm, Volume 6, Issue 8, August 2025.
A schematic illustration of the pathogenesis and emerging therapeutic strategies for OA, including: risk factors and molecular mechanisms of OA, joint changes between healthy and OA conditions, and current emerging therapeutic approaches for OA. Abbreviations: IA: intra‐articular injection; EVs: extracellular vesicles. ABSTRACT Osteoarthritis (OA) is a
Wei Liu   +3 more
wiley   +1 more source

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