Results 71 to 80 of about 44,980 (368)
Xanthines as a scaffold for molecular diversity [PDF]
, 2018 Summary: Xanthines represent a new, versatile scaffold for combinatorial chemistry. A five-step solid-phase synthesis of xanthine derivatives is described which includes alkylations, a nucleophilic displacement reaction at a heterocycle and a ring ...
Eberle, Alex, Heizmann, Gerhard
core
Impact of doxofylline compared to theophylline in asthma: A pooled analysis of functional and clinical outcomes from two multicentre, double-blind, randomized studies (DOROTHEO 1 and DOROTHEO 2) [PDF]
, 2018 This pooled analysis of double-blind, randomized, placebo-controlled trials aimed to investigate the impact of DOxofylline compaRed tO THEOphylline (DOROTHEO 1 and DOROTHEO 2 studies) on functional and clinical outcomes in asthma.
Frank L. Dini +6 more
core +1 more source
Advanced Science, EarlyView.This study have loaded chiral gold nanoclusters onto the inner and outer surfaces of ZIF and uncovers the biodistribution, metabolic variances, and therapeutic mechanism of chiral nanoparticles, providing deep insights into the nanobiological effects of chiral anti‐inflammatory nanomedicines in PD therapy for future clinical transformation.
Junyang Chen +7 more
wiley +1 more source
Antioxidants, 2022 Hypertension is considered to be both a cardiovascular disease and a risk factor for other cardiovascular diseases, such as coronary ischemia or stroke. In many cases, hypertension occurs in the context of metabolic syndrome (MetS), a condition in which ...
Mario de la Fuente Muñoz +9 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad +9 more
wiley +1 more source
Influence of xanthines on gastroesophageal reflux in infants at risk for sudden infant death syndrome [PDF]
, 1986 A
De Wolf, Daniël +2 more
core +1 more source
Clay body wrap with microcurrent: effects in central adiposity [PDF]
, 2013 Introduction Increased fat mass is becoming more prevalent in women and its accumulation in the abdominal region can lead to numerous health risks such as diabetes mellitus.
Couto, Miriam F. +4 more
core +1 more source
Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism
Annals of Neurology, EarlyView.Objective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by altered metabolome and energy homeostasis, manifesting with body mass index changes and hypermetabolism—both prognostic of disease progression and survival.
Kai Guo +7 more
wiley +1 more source
Caffeine Consumption through Coffee: Content in the Beverage, Metabolism, Health Benefits and Risks
Beverages, 2019 Caffeine (1,3,7-trimethylxanthine) is the most consumed psychoactive substance in the world, acting by means of antagonism to adenosine receptors, mainly A1 and A2A.
Juliana dePaula, Adriana Farah
doaj +1 more source
Frontiers in Pharmacology, 2022 Purpose: Inhaled Corticosteroids (ICSs) and oral Leukotriene Receptor Antagonists (LTRAs) are commonly prescribed asthma preventers, however, concerns have been raised as to whether montelukast (LTRA) is associated with an increase in occurrences of ...
Min Sook Seo +6 more
doaj +1 more source