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Splenic cDC1 efferocytosis and cross-presentation to CD8 T cells are promoted by GPR34 and lysophosphatidylserine. [PDF]
Tam H, Shen H, Xu Y, An J, Cyster JG.
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Editorial: A new perspective on the importance of dendritic cells in cancer immunity: from bench to patient's bedside. [PDF]
Galati D, Amoozgar Z, Ni L.
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HMGA2 links morphological evolution and microenvironment dynamics to systemic therapy response in clear cell renal cell carcinoma. [PDF]
Nakamoto T +9 more
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The multifaceted role of XCL1 in health and disease. [PDF]
Syed M +3 more
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Myeloid-driven immunosuppression in head and neck cancer: single-cell ATAC/RNA and spatial transcriptomic perspectives. [PDF]
Luo R, Yang J, Cao Z, Li B.
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Critical Roles of a Dendritic Cell Subset Expressing a Chemokine Receptor, XCR1
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XCL1 and XCR1 in the immune system
Microbes and Infection, 2012XCL1, a C class chemokine also known as lymphotactin, is produced by T, NK, and NKT cells during infectious and inflammatory responses, whereas XCR1, the receptor of XCL1, is expressed by a dendritic cell subpopulation. The XCL1-XCR1 axis plays an important role in dendritic-cell-mediated cytotoxic immune response.
Yu, Lei, Yousuke, Takahama
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