Results 101 to 110 of about 7,168 (188)

Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells [PDF]

, 2016
In vitro generation of dendritic-like cells through differentiation of peripheral blood monocytes is typically done using two-dimensional polystyrene culture plates.
Brogaard, Louise, Emnéus, Jenny, Flagstad, Frederikke Bjergvang, Hartmann, Sofie Bruun, Jungersen, Gregers, Mohanty, Soumyaranjan, Skovgaard, Kerstin, Summerfield, Artur, Wolff, Anders   +8 more
core   +3 more sources

Novel Cre-Expressing Mouse Strains Permitting to Selectively Track and Edit Type 1 Conventional Dendritic Cells Facilitate Disentangling Their Complexity in vivo

Frontiers in Immunology, 2018
Type 1 conventional DCs (cDC1) excel in the cross-priming of CD8+ T cells, which is crucial for orchestrating efficient immune responses against viruses or tumors.
Raphaël Mattiuz, Christian Wohn, Sonia Ghilas, Marc Ambrosini, Yannick O. Alexandre, Cindy Sanchez, Anissa Fries, Thien-Phong Vu Manh, Bernard Malissen, Bernard Malissen, Marc Dalod, Karine Crozat   +11 more
doaj   +1 more source

CD8+XCR1neg Dendritic Cells Express High Levels of Toll-Like Receptor 5 and a Unique Complement of Endocytic Receptors

Frontiers in Immunology, 2019
Conventional dendritic cells (cDC) resident in the lymphoid organs of mice have been classically divided into CD8+ and CD8neg subsets. It is well-established that CD8+ dendritic cells (DCs) and their migratory counterparts in the periphery comprise the ...
Ben Wylie, James Read, Anthony C. Buzzai, Teagan Wagner, Niamh Troy, Genevieve Syn, Shane R. Stone, Bree Foley, Anthony Bosco, Mark N. Cruickshank, Jason Waithman   +10 more
doaj   +1 more source

A DNA Prime Immuno-Potentiates a Modified Live Vaccine against the Porcine Reproductive and Respiratory Syndrome Virus but Does Not Improve Heterologous Protection

Viruses, 2019
The porcine reproductive and respiratory syndrome virus (PRRSV), an RNA virus inducing abortion in sows and respiratory disease in young pigs, is a leading infectious cause of economic losses in the swine industry.
Cindy Bernelin-Cottet, Céline Urien, Maxence Fretaud, Christelle Langevin, Ivan Trus, Luc Jouneau, Fany Blanc, Jean-Jacques Leplat, Céline Barc, Olivier Boulesteix, Mickaël Riou, Marilyn Dysart, Sophie Mahé, Elisabeth Studsrub, Hans Nauwynck, Nicolas Bertho, Olivier Bourry, Isabelle Schwartz-Cornil   +17 more
doaj   +1 more source

Concepts of GPCR-controlled navigation in the immune system

, 2019
G-protein-coupled receptor (GPCR) signaling is essential for the spatiotemporal control of leukocyte dynamics during immune responses. For efficient navigation through mammalian tissues, most leukocyte types express more than one GPCR on their surface ...
Boneschansker L, Brandt SL, Chan EC, Filippo K, Freedman NJ, Hjorto GM, Hons M, Katakai T, Kitayama J, Lemos C, Ley K, Miyabe Y, Moussavi‐Harami SF, Proudfoot AEI, Purvanov V, Rot A, Scheiermann C, Schwarz J, Sokol CL, Sotsios Y, Steury MD, Takeda A, Thiriot A, Tomhave ED, Wang Y, Yanagihara S, Zhang Y   +26 more
core   +1 more source

Expression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis.

, 2013
International audienceBACKGROUND AND AIMS: Infection by hepatitis C virus is a worldwide health problem. An inadequate Th2 cytokine response promotes the fibrosis-cirrhosis fate. Immune-modulating molecules favoring a Th2 profile, such as HLA-G molecules
Amiot, Laurence, Chalmel, Frédéric, Gascan, Hugues, Guyader, Dominique, Helgoualc'H, Annie L', Rauch, Michel, Samson, Michel, Turlin, Bruno, Vu, Nicolas   +8 more
core   +3 more sources

The herpesvirus 8 encoded chemokines vCCL2 (vMIP-II) and vCCL3 (vMIP-III) target the human but not the murine lymphotactin receptor

Virology Journal, 2008
Background Large DNA-viruses such as herpesvirus and poxvirus encode proteins that target and exploit the chemokine system of their host. The Kaposi sarcoma- associated herpes virus (KSHV) encodes three chemokines.
Lüttichau Hans R
doaj   +1 more source

Cross-presentation of cell-associated antigens by MHC class I in dendritic cell subsets

Frontiers in Immunology, 2015
Dendritic cells have the unique ability to pick up dead cells carrying antigens in tissue and migrate to the lymph nodes where they can cross-present cell-associated antigens by MHC class I to CD8+ T cells. There is strong in vivo evidence that the mouse
Enric eGutiérrez-Martínez, Remi ePlanès, Giorgio eAnselmi, Matthew eReynolds, Shinelle eMenezes, Adiko Assi Aimé Cézaire, Adiko Assi Aimé Cézaire, Loredana eSaveanu, Loredana eSaveanu, Pierre eGuermonprez   +9 more
doaj   +1 more source

The islet-resident macrophage is in an inflammatory state and senses microbial products in blood [PDF]

, 2017
Aggarwal, Amit, Amit, Anders, Andrade, Banaei-Bouchareb, Boris Calderon, Buxadé, Calderon, Calderon, Calderon, Carrero, Castellino, Chee, Chen, Chevrier, Christen, del Rey, Diana, Diana, Dinarello, Dobin, Droop, Dror, Dufour, Emil R. Unanue, Ewald, Ferris, Foster, Fridovich, García, Gautier, Gilchrist, Greeley, Griffith, Haldar, Harrow, Heng, Javier A. Carrero, Johnson, Kaikkonen, Kanehisa, Kawai, Kim, Koblansky, Kotas, Kurth, Kägi, Lavin, Litvak, Love, Mandrup-Poulsen, Markle, Matloubian, Maxim N. Artyomov, Melli, Mi, Mi, Miller, Mootha, Moratz, Oldenburg, Pakala, Park, Pasparakis, Pavel N. Zakharov, Reddy, Reif, Ritchie, Rütti, Schott, Smyth, Stephen T. Ferris, Subramanian, Suri, Tai, Terauchi, Thomas, Vomund, Wen, Wood, Wu, Xiaoxiao Wan, Yamada, Yang, Yosef, Yosef, Yurkovetskiy, Zhao   +88 more
core   +2 more sources

Cytokines and therapy in COPD: a promising combination? [PDF]

, 2002
COPD is a major health problem, with patients showing a progressively declining, largely irreversible, change in lung function. This is associated with chronic airways inflammation and structural remodeling, including loss of alveolar ...
Boer, W.I. (Pim) de
core   +1 more source