Results 81 to 90 of about 5,269 (176)

Systematic pan-cancer analysis reveals XCR1 as a Prognostic and Immunological Biomarker

, 2023
Abstract Background Chemokines and their receptors play an important role in immune monitoring and immune defense during the tumor growth and metastasis. However, their prognostic roles in pan-cancer were not elucidated. In this work, we screened all chemokine receptors in pan-cancer and discovered XCR1 as a reliable immunological and ...
Likun Cui, Jie Chen, Chunzhen Li, Yizhi Yu, Sheng Xu   +4 more
openaire   +1 more source

Velociraptor Machine Learning Quantifies Similarity to Known Cell Types and Matches Cells Across Flow and Imaging Cytometry Platforms

Cytometry Part A, Volume 109, Issue 9, Page 649-663, September 2026.
ABSTRACT Suspension flow cytometry enables high‐throughput cellular profiling at the single cell level, but these data lack positional information. Conversely, tissue‐based imaging cytometry techniques reveal a cell's location within the tissue architecture and can provide insight into cell biology.
Claire E. Cross, Asa A. Brockman, Rebecca A. Ihrie, Jonathan M. Irish   +3 more
wiley   +1 more source

Large-Scale Human Dendritic Cell Differentiation Revealing Notch-Dependent Lineage Bifurcation and Heterogeneity

Cell Reports, 2018
Summary: The ability to generate large numbers of distinct types of human dendritic cells (DCs) in vitro is critical for accelerating our understanding of DC biology and harnessing them clinically. We developed a DC differentiation method from human CD34+
Sreekumar Balan, Catharina Arnold-Schrauf, Abdenour Abbas, Norbert Couespel, Juliette Savoret, Francesco Imperatore, Alexandra-Chloé Villani, Thien-Phong Vu Manh, Nina Bhardwaj, Marc Dalod   +9 more
doaj   +1 more source

XCR1 Venus Dendritic cell in explanted lymph node

, 2016
60 frame time series of XCR1 Venus Dendritic Cell imaged within explanted lymph node using Nikon A1R.
Henry Pinkard (2552305), Krummel, Matthew F., Matthew F. Krummel (339588), Corbin, Kaitlin, Pinkard, Henry, Kaitlin Corbin (2552308)   +5 more
core   +1 more source

High‐dimensional spectral flow cytometry uncovers progressive T‐cell exhaustion and myeloid cell reprogramming in a CLL mouse model

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Chronic lymphocytic leukemia (CLL) exhibits marked clinical heterogeneity that cannot be fully explained by genetic alterations, underscoring the critical role of the tumor microenvironment in disease progression and therapeutic resistance.
Hannah Briesch, Mariana Coelho, Alessia Floerchinger, Yuliia Borysovych, Nicolas Aubert, Daniel Medina‐Gil, Manina Breitinger, Marc Zapatka, Stella E. Autenrieth, Martina Seiffert   +9 more
wiley   +1 more source

Additional file 2: of Tolerogenic XCR1+ dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis

, 2019
Figure S2. Frequency of splenic XCR1+ cDCs is similar in B7-Tg rats than in NTG rats at 6 month. CD103+cDCs were isolated from the spleen of 6-month-old NTG, B7-Tg, and B27-Tg rats. XCR1 frequency was evaluated in CD4− cDCs by flow cytometry.
Simon Glatigny (39155), Hendrick Mambu Mambueni (6295715), Gilles Chiocchia (39162), Maxime Breban (23460), Luiza Araujo (6295721), Vânia Camilo (6295709), Nadège Jah (6295703), Kétia Ermoza (6295700)   +7 more
core   +1 more source

Cytomegalovirus expresses the chemokine homologue vXCL1 capable of attracting XCR1+CD4- dendritic cells [PDF]

, 2013
Cytomegaloviruses (CMV) have developed various strategies to escape the immune system of the host. One strategy involves the expression of virus-encoded chemokines to modulate the host chemokine network.
Weise, Christoph, Mages, Hans Werner, Geyer, Henriette, Belužić, Robert, Jonjić, Stipan, Voigt, Sebastian, Kroczek, Richard, Vugrek, Oliver, Hartung, Evelyn   +8 more
core   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, Volume 55, Issue 3, Page 406-421, September 2026.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source

Data for: Genetic diversity of chemokine XCL1 and its receptor XCR1 in murine rodents

, 2019
Data for: Genetic diversity of chemokine XCL1 and its receptor XCR1 in murine ...
Feifei Xu (586431), Cody Thompson (6662321), Ruihong Ning (3391565), Dawei Wang (471687), Yan Li (23143), Ying Li (38224), Dan He (145755), Bo Zeng (428742)   +7 more
core   +1 more source

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development [PDF]

, 2011
Dendritic cells (DCs) in the thymus (tDCs) are predominantly accumulated in the medulla and contribute to the establishment of self-tolerance. However, how the medullary accumulation of tDCs is regulated and involved in self-tolerance is unclear. We show
Ishimaru, N., Hollander, G. A., Naozumi Ishimaru, Hayashi, Y., Rene de Waal Malefyt, Nitta, T., Yu Lei, Lei, Y., Jeker, L. T., Georg A. Holländer, Bosl, M. R., Yoshio Hayashi, Yousuke Takahama, Takahama, Y., Michael R. Bösl, Lukas T. Jeker, Takeshi Nitta, Nagasawa, T., Izumi Ohigashi, Ripen, A. M., Ohigashi, I., Takashi Nagasawa, Malefyt Rde, W., Adiratna Mat Ripen, Nitta, Takeshi, Ripen, Adiratna Mat, Bösl, Michael R., Lei, Yu, de Waal Malefyt, Rene, Jeker, Lukas T., Ishimaru, Naozumi, Hayashi, Yoshio, Takahama, Yousuke, Ohigashi, Izumi, Nagasawa, Takashi, Holländer, Georg A.   +35 more
core   +1 more source