Results 91 to 100 of about 672 (110)

Shared autonomous HERV loci transcription identifies a unique circulating CD14+-xCR1+ mononuclear cell phenotype in a patient group with post-acute sequelae of COVID-19.

PLoS ONE
The human genome contains approximately 3,200 near full-length autonomous human endogenous retroviral (HERV) loci capable of transcriptional activation through long terminal repeats.
Hyunmin Koo, Casey D Morrow
doaj   +1 more source

Cutting edge: expression of XCR1 defines mouse lymphoid-tissue resident and migratory dendritic cells of the CD8α+ type.

, 2011
International audienceSubsets of dendritic cells (DCs) have been described according to their functions and anatomical locations. Conventional DC subsets are defined by reciprocal expression of CD11b and CD8α in lymphoid tissues (LT), and of CD11b and ...
Samira Tamoutounour, Bjarne Bogen, Thien-Phong Vu Manh, Martin Guilliams, Hervé Luche, Crozat, Karine, Bernard Malissen, Azukizawa, Hiroaki, Manh, Thien-Phong Vu, Malissen, Bernard, Even Fossum, Sandrine Henri, Fossum, Even, Henri, Sandrine, Marc Dalod, Bogen, Bjarne, Ardouin, Laurence, Hiroaki Azukizawa, Karine Crozat, Guilliams, Martin, Laurence Ardouin, Luche, Hervé, Dalod, Marc, Tamoutounour, Samira   +23 more
core   +1 more source

Intratumoral sustained release of resiquimod with ablative fractional laser induces efficacy in a cutaneous squamous cell carcinoma mouse model

Frontiers in Immunology
IntroductionThe Toll-like receptor (TLR) 7/8 agonist resiquimod has shown promise for precancerous lesions of cutaneous squamous cell carcinoma (cSCC) but remains unexplored as a treatment for cSCC.
Martin Wiinberg, Fredrik Melander, Catharina M. Lerche, Catharina M. Lerche, Thomas L. Andresen, Uffe H. Olesen, Merete Haedersdal   +6 more
doaj   +1 more source

Additional file 5: of Tolerogenic XCR1+ dendritic cell population is dysregulated in HLA-B27 transgenic rat model of spondyloarthritis

, 2019
Figure S5. Number of XCR1− cDCs in 6-month-old B27-Tg rat MLN after TLR-7 stimulation. Low-density cells were isolated from 6-month-old NTG and B27-Tg rats MLN that had been fed 5 h before with the TLR-7 agonist R-848 to activate DC migration from the ...
Simon Glatigny (39155), Hendrick Mambu Mambueni (6295715), Gilles Chiocchia (39162), Maxime Breban (23460), Luiza Araujo (6295721), Vânia Camilo (6295709), Nadège Jah (6295703), Kétia Ermoza (6295700)   +7 more
core   +1 more source

Immunotherapy of chronic virus infections : Exhausted CD8+ T cell subsets are differentially regulated by XCR1 + DC

The contribution of cross-presenting XCR1+ dendritic cells (DC) in maintaining T cell function during exhaustion and immuno-therapeutic interventions of chronic infections remains poorly characterized.
Domenjó Vila, Eva
core  

T-cell-derived XCL1 Facilitates Their Interaction With XCR1+ DC's During WNV Encephalitis [PDF]

West Nile virus (WNV), a mosquito-borne flavivirus, is the leading cause of arboviral- induced encephalitis in the United States. While most infections are asymptomatic, some patients develop symptoms that range from febrile illness to more severe ...
Kristen De La Torre
core  

XCR1+ DC cells in HLA-B27 transgenic rat model of spondyloarthritis

, 2018
La spondyloarthrite (SpA) est une maladie chronique inflammatoire affectant principalement les articulations axiales et périphériques et parfois des organes extra-articulaires comme les intestins.
Ermoza, Kétia
core  

Harnessing human cross-presenting CLEC9A+XCR1+ dendritic cells for immunotherapy

Frontiers in Immunology, 2014
Kirsteen eTullett, Kirsteen eTullett, Kirsteen eTullett, Mireille eLahoud, Mireille eLahoud, Kristen J Radford, Kristen J Radford   +6 more
doaj   +1 more source

XCR1 expression distinguishes human conventional dendritic cell type 1 with full effector functions from their immediate precursors [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2023
Dendritic cells (DCs) are major regulators of innate and adaptive immune responses. DCs can be classified into plasmacytoid DCs and conventional DCs (cDCs) type 1 and 2. Murine and human cDC1 share the mRNA expression of XCR1.
Lukas Heger, Christian Lehmann, Diana Dudziak   +2 more
exaly   +3 more sources

Functional expression of the chemokine receptor XCR1 on oral epithelial cells

Journal of Pathology, 2010
Chemokines are chemoattractant cytokines which act on specific receptors and play an important role in leukocyte migration as well as physiological and pathological processes.
Craig Murdoch, Ali Khurram, Simon Whawell   +2 more
exaly   +2 more sources