Results 11 to 20 of about 16,717 (221)

Linking Chromosomal Silencing With Xist Expression From Autosomal Integrated Transgenes [PDF]

Frontiers in Cell and Developmental Biology, 2021
Xist is the master regulator of X-Chromosome Inactivation (XCI), the mammalian dosage compensation mechanism that silences one of the two X chromosomes in a female cell. XCI is established during early embryonic development.
Ikrame Naciri, Benjamin Lin, Chiu-Ho Webb, Shan Jiang, Sarah Carmona, Wenzhu Liu, Ali Mortazavi, Sha Sun   +7 more
doaj   +2 more sources

XIST/Xist-induced epigenetic events in somatic cells

, 2010
Mammalian dosage compensation of X-linked genes is achieved between XX females and XY males by silencing one of the two X chromosomes. It is the expression of a functional non-coding RNA transcript, XIST that is responsible for the initiation of silencing during X-chromosome inactivation. XIST expression and subsequent in cis localization to the future
Thorogood, Nancy P.
core   +3 more sources

Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression

Genome Research
Xist long noncoding RNA is the master regulator of the X-Chromosome inactivation (XCI) process. Xist is expressed from the inactive X and coats the inactive X to facilitate XCI. Cis-regulation of Xist expression remains poorly understood in the context of maintenance of XCI.
Sudeshna Majumdar, Lakshmi Sowjanya Bammidi, Hemant C. Naik, Avinchal Manhas, Runumi Baro, Akash Kalita, Amlan Jyoti Naskar, Sundarraj Nidharshan, Girija S. Bariha, Dimple Notani, Srimonta Gayen   +10 more
openaire   +4 more sources

How does the Xist activator Rlim/Rnf12 regulate Xist expression?

Biochemical Society Transactions
The long non-coding RNA (lncRNA) Xist is crucially involved in a process called X chromosome inactivation (XCI), the transcriptional silencing of one of the two X chromosomes in female mammals to achieve X dosage compensation between the sexes. Because Xist RNA silences the X chromosome from which it is transcribed, the activation of Xist transcription
Feng Wang, Poonam Mehta, Ingolf Bach
openaire   +3 more sources

XIST: An XML Index Selection Tool [PDF]

, 2004
XML indices are essential for efficiently processing XML queries which typically have predicates on both structures and values. Since the number of all possible structural and value indices is large even for a small XML document with a simple structure, XML DBMSs must carefully choose which indices to build.
Kanda Runapongsa, Jignesh M. Patel, Rajesh Bordawekar, Sriram Padmanabhan   +3 more
openaire   +3 more sources

Maintenance of Xist Imprinting Depends on Chromatin Condensation State and Rnf12 Dosage in Mice. [PDF]

PLoS Genetics, 2016
In female mammals, activation of Xist (X-inactive specific transcript) is essential for establishment of X chromosome inactivation. During early embryonic development in mice, paternal Xist is preferentially expressed whereas maternal Xist (Xm-Xist) is ...
Atsushi Fukuda, Atsushi Mitani, Toshiyuki Miyashita, Takashi Sado, Akihiro Umezawa, Hidenori Akutsu   +5 more
doaj   +1 more source

Interfering lncRNA XIST inhibits the growth of salivary adenoid cystic carcinoma cells and improves cisplatin sensitivity by up-regulating miR-429 [PDF]

Xin yixue, 2022
ObjectiveTo investigate the regulatory effect and mechanism of lncRNA XIST on salivary adenoid cystic carcinoma （SACC） cell growth and cisplatin （DDP） chemosensitivity.
Zhang Xuan, Ma Licheng, Sun Longxiao, Zhang Lei
doaj   +1 more source

Long non-coding RNA XIST: a novel oncogene in multiple cancers

Molecular Medicine, 2021
Long non-coding RNA (lncRNA) X-inactive specific transcript (XIST) is an important lncRNA derived from the XIST gene in mammals. XIST is abnormally expressed in numerous tumors, in most of which XIST functions as an oncogene. XIST is involved in multiple
Jun Yang, Manlong Qi, Xiang Fei, Xia Wang, Kefeng Wang   +4 more
doaj   +1 more source

The role of the Xist 5’ m6A region and RBM15 in X chromosome inactivation [version 1; peer review: 1 approved, 2 approved with reservations]

Wellcome Open Research, 2020
Background: X chromosome inactivation in mammals is regulated by the non-coding (nc) RNA, Xist, which represses the chromosome from which it is transcribed.
Heather Coker, Guifeng Wei, Benoit Moindrot, Shabaz Mohammed, Tatyana Nesterova, Neil Brockdorff   +5 more
doaj   +1 more source

XiSTS [PDF]

Proceedings of the 2nd workshop on NLP and XML - NLPXML '02, 2002
This paper describes the use of XML in three generic interacting speech technology systems. The first, a phonological syllable recognition system, generates feature-based finite-state automaton representations of phonotactic constraints in XML. It employs axioms of event logic to interpret multilinear representations of speech utterances and outputs ...
Michael Walsh 0001, Stephen Wilson, Julie Carson-Berndsen   +2 more
openaire   +2 more sources