Results 71 to 80 of about 3,060 (172)

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, Volume 12, Issue 40, October 27, 2025.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

Advanced Science, Volume 12, Issue 40, October 27, 2025.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu, Dongqin Ding, Huiying Wang, Xinyi Ren, Sang Yup Lee, Dawei Zhang   +5 more
wiley   +1 more source

Regulation of Pentose Catabolic Pathway Genes of Aspergillus niger

Food Technology and Biotechnology, 2007
The aim of this study was to obtain a better understanding of the pentose catabolism in Aspergillus niger and the regulatory systems that affect it. To this end, we have cloned and characterised the genes encoding A. niger L-arabitol dehydrogenase (ladA)
Marco J.L. de Groot, Carline van den Dool, Han A.B. Wösten, Mark Levisson, Patricia A. vanKuyk, George J.G. Ruijter, Ronald P. de Vries   +6 more
doaj  

Genome-Wide Identification and Characterization of the Medium-Chain Dehydrogenase/Reductase Superfamily of Trichosporon asahii and Its Involvement in the Regulation of Fluconazole Resistance

Journal of Fungi
The medium-chain dehydrogenase/reductase (MDR) superfamily contains many members that are widely present in organisms and play important roles in growth, metabolism, and stress resistance but have not been studied in Trichosporon asahii.
Xiaoping Ma, Zhen Liu, Xiangwen Zeng, Zhiguo Li, Rongyan Luo, Ruiguo Liu, Chengdong Wang, Yu Gu   +7 more
doaj   +1 more source

Optimization of fermentation technology and anti-fatigue characteristics of sea buckthorn-passion fruit compound beverage [PDF]

Zhongguo niangzao
Sea buckthorn-passion fruit compound beverage was prepared with sea buckthorn and passion fruit as raw materials, Saccharomyces cerevisiae and Lactiplantibacillus plantarum (1∶1) as fermentation strains.
MA Yong, MU Yongli, ZHOU Shuo, RAN Junjian
doaj   +1 more source

Pichia stipitis xylose reductase helps detoxifying lignocellulosic hydrolysate by reducing 5-hydroxymethyl-furfural (HMF)

Biotechnology for Biofuels, 2008
Background Pichia stipitis xylose reductase (Ps-XR) has been used to design Saccharomyces cerevisiae strains that are able to ferment xylose. One example is the industrial S. cerevisiae xylose-consuming strain TMB3400, which was constructed by expression
Röder Anja, Modig Tobias, Almeida João RM, Lidén Gunnar, Gorwa-Grauslund Marie-F   +4 more
doaj   +1 more source

Promiscuous activities of heterologous enzymes lead to unintended metabolic rerouting in Saccharomyces cerevisiae engineered to assimilate various sugars from renewable biomass

Biotechnology for Biofuels, 2018
Background Understanding the global metabolic network, significantly perturbed upon promiscuous activities of foreign enzymes and different carbon sources, is crucial for systematic optimization of metabolic engineering of yeast Saccharomyces cerevisiae.
Eun Ju Yun, Eun Joong Oh, Jing-Jing Liu, Sora Yu, Dong Hyun Kim, Suryang Kwak, Kyoung Heon Kim, Yong-Su Jin   +7 more
doaj   +1 more source

Xylitol dehydrogenase mutants ofPachysolen tannophilusand the role of xylitol in d-xylose catabolism [PDF]

FEMS Microbiology Letters, 1983
Maleszka, R., Neirinck, L., James, A., Rutten, H., Schneider, H.   +4 more
openaire   +2 more sources

Purification and properties of the xylitol dehydrogenase from Pullularia pullulans.

Anais da Academia Brasileira de Ciencias, 1981
Pullularia pullulans grown on D-xylose induces the synthesis of a xylitol dehydrogenase capable of oxidizing xylitol to D-xylulose in the presence of NAD according to the following reaction: Xylitol + NAD+ in equilibrium to D-xylulose + NADH + H+. Cells grown on D-glucose do not show appreciably xylitol dehydrogenase activity. However, synthesis of the
J K, Sugai, L A, Veiga
openaire   +1 more source

Improving xylitol production by semi-rational engineering of xylitol dehydrogenase and optimizing cofactor regeneration in Gluconobacter oxydans

BMC Biotechnology
Abstract Background Xylitol, a widely used sugar substitute in food and medicine, can be produced through microbial bioconversion using glucose as the primary substrate. In this process, a critical factor limiting xylitol production is the relatively low activity of xylitol dehydrogenase (XDH) during the ...
Jun-Hao Su, Jin-Cheng Guo, Lu Liu, Hai-Ling Zhang, Dong Liu   +4 more
openaire   +1 more source