Results 101 to 110 of about 23,621 (250)

Meningioma: current updates on genetics, classification, and mouse modeling

Upsala Journal of Medical Sciences
Meningiomas, the most common primary brain tumors in adults, are often benign and curable by surgical resection. However, a subset is of higher grade, shows aggressive growth behavior as well as brain invasion, and often recurs even after several rounds ...
Frank Szulzewsky, H. Nayanga Thirimanne, Eric C. Holland   +2 more
doaj   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

Brain Pathology, EarlyView.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan, Michael E. Buckland, Geeta Chacko, Kenta Masui, Junji Shibahara, Vani Santosh, Maysa Al‐Hussaini, Sung‐Hye Park, Tarik Tihan, Ho‐Keung Ng, Pieter Wesseling, David N. Louis, Chitra Sarkar, Takashi Komori   +13 more
wiley   +1 more source

Die Funktion von YAP1 in der Progredienz des Neuroblastoms

, 2022
Neuroblastoma is a pediatric solid tumor, that originates from the developing sympathetic nervous system and typically occurs in the adrenal medulla and paraspinal ganglia with secondary locations in the bone marrow and lymph nodes among others.
Ahrens, Kerstin
core   +1 more source

Inhibition of Yes-Associated Protein-1 (YAP1) Enhances the Response of Invasive Breast Cancer Cells to the Standard Therapy

Breast Cancer: Targets and Therapy, 2020
Maha Guimei,1,2 Sana Alrouh,3 Maha Saber-Ayad,2– 4 Shirin A Hafezi,3 Arya Vinod,3 Surendra Rawat,3 Yazan Wardeh,5 Tala Mohamad Bakkour,5 Ahmed Taher El-Serafi3,6,7 1Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria ...
Guimei M, Alrouh S, Saber-Ayad M, Hafezi SA, Vinod A, Rawat S, Wardeh Y, Bakkour TM, El-Serafi AT   +8 more
doaj  

The nitty‐gritty of vascular permeability in cancer: targeting blood endothelium to control metastases

British Journal of Pharmacology, EarlyView.
Blood vascular permeability is a hallmark of cancer and acts as an active driver of metastatic dissemination. Metastasis accounts for the vast majority of cancer deaths, yet most work has focussed on tumour‐intrinsic traits and angiogenesis, while the specific contribution of endothelial barrier regulation to intravasation and extravasation remains ...
Pierre Boucher, Mérone Da Costa Oliveira, Adrien Levesque, Alexandre Rutault, Patrick Savoyaud, Nicolas Bréchot, Stéphane Germain   +6 more
wiley   +1 more source

Image4_Hydrostatic Pressure Controls Angiogenesis Through Endothelial YAP1 During Lung Regeneration.TIFF

, 2022
Pulmonary artery (PA) pressure increases during lung growth after unilateral pneumonectomy (PNX). Mechanosensitive transcriptional co-activator, yes-associated protein (YAP1), in endothelial cells (ECs) is necessary for angiogenesis during post-PNX lung ...
Priscilla Kyi (11497909), Kienna Matus (11497906), Tadanori Mammoto (72440), Kathryn Hendee (11497903), Sridhar Rao (3534197), Diana M. Tabima (12104945), Akiko Mammoto (148118), Sang H. Lee (7455065), Tendai Hunyenyiwa (11497900), Naomi C. Chesler (12104948)   +9 more
core   +1 more source

Organ‐Specific Cancer‐Associated Fibroblast Subtypes Across the Digestive System Linked to Cancer Hallmarks

Cancer Science, EarlyView.
We integrated 14 single‐cell RNA‐seq datasets and 18 bulk cohorts to define eight CAF subtypes in GI cancers. myCAF1 and myCAF2 promoted immunosuppressive, poor‐prognosis niches, whereas iCAF1 was linked to favorable prognosis and antitumor immunity.
Huaitao Wang, Takashi Semba, Atsuko Yonemura, Hiroshi Naito, Lingfeng Fu, Takuya Tajiri, Masaaki Iwatsuki, Takatsugu Ishimoto   +7 more
wiley   +1 more source

Targeting Egfr‐Mediated Cell Proliferation and Lipid Metabolism Separation Effectively Accelerate Liver Regeneration

Cell Proliferation, EarlyView.
AREG coordinates cell proliferation and lipid metabolism reprogramming during liver regeneration and targeting lipid metabolism can promote liver regeneration. ABSTRACT Hepatocyte proliferation restores liver mass after partial hepatectomy (PHx), but the metabolic cost of this process remains unclear.
Yuelei Hu, Shifei Song, Ruilin Wang, Ni An, Jinmei Diao, Yuguo Chen, Juan Liu, Guoyue Lv   +7 more
wiley   +1 more source

Image5_Hydrostatic Pressure Controls Angiogenesis Through Endothelial YAP1 During Lung Regeneration.TIFF

, 2022
Pulmonary artery (PA) pressure increases during lung growth after unilateral pneumonectomy (PNX). Mechanosensitive transcriptional co-activator, yes-associated protein (YAP1), in endothelial cells (ECs) is necessary for angiogenesis during post-PNX lung ...
Priscilla Kyi (11497909), Kienna Matus (11497906), Tadanori Mammoto (72440), Kathryn Hendee (11497903), Sridhar Rao (3534197), Diana M. Tabima (12104945), Akiko Mammoto (148118), Sang H. Lee (7455065), Tendai Hunyenyiwa (11497900), Naomi C. Chesler (12104948)   +9 more
core   +1 more source

Merkel Cell Carcinoma With Divergent Differentiation—Or Something Else? A Triphasic Cutaneous Carcinoma With Lineage Plasticity

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous neuroendocrine carcinoma that typically arises in sun‐exposed skin of older or immunosuppressed patients. Combined or collision tumors involving MCC and other cutaneous malignancies are uncommon, and tumors exhibiting more than two distinct malignant phenotypes are exceptionally rare.
Zeinab Khalil, Hozaifa Elameen, Ahmed K. Alomari   +2 more
wiley   +1 more source