Results 21 to 30 of about 257,444 (202)
Microorganisms, 2023 In the long history of microorganism use, yeasts have been developed as hosts for producing biologically active compounds or for conventional fermentation.
Seiji Shibasaki, Mitsuyoshi Ueda
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Yeast Surface-Displayed H5N1 Avian Influenza Vaccines [PDF]
Journal of Immunology Research, 2016 Highly pathogenic H5N1 avian influenza viruses pose a pandemic threat to human health. A rapid vaccine production against fast outbreak is desired. We report, herein, a paradigm-shift influenza vaccine technology by presenting H5N1 hemagglutinin (HA) to the surface of yeast.
Han Lei +4 more
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A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity [PDF]
, 2020 Malaria is a global health concern and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum ...
Bosch, A. +15 more
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Microbiology Spectrum, 2015 ABSTRACT Despite the availability of antimicrobial drugs, the continued development of microbial resistance—established through escape mutations and the emergence of resistant strains—limits their clinical utility. The discovery of novel, therapeutic, monoclonal antibodies (mAbs) offers viable clinical alternatives in the ...
Jared, Sheehan, Wayne A, Marasco
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Global transposable characteristics in the yeast complete DNA sequence [PDF]
, 2010 Global transposable characteristics in the complete DNA sequence of the Saccharomyces cevevisiae yeast is determined by using the metric representation and recurrence plot methods.
Wu, Zuo-Bing
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The replicative lifespan-extending deletion of SGF73 results in altered ribosomal gene expression in yeast. [PDF]
, 2017 Sgf73, a core component of SAGA, is the yeast orthologue of ataxin-7, which undergoes CAG-polyglutamine repeat expansion leading to the human neurodegenerative disease spinocerebellar ataxia type 7 (SCA7).
Garza, Renee M +6 more
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Strategies to Screen Anti-AQP4 Antibodies from Yeast Surface Display Libraries
Antibodies, 2022 A rapid and effective method to identify disease-specific antibodies from clinical patients is important for understanding autoimmune diseases and for the development of effective disease therapies.
Aric Huang +11 more
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Smc5/6: a link between DNA repair and unidirectional replication? [PDF]
, 2008 Of the three structural maintenance of chromosome (SMC) complexes, two directly regulate chromosome dynamics. The third, Smc5/6, functions mainly in homologous recombination and in completing DNA replication.
A Losada +46 more
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Selection and characterization of FcεRI phospho-ITAM specific antibodies
mAbs, 2019 Post-translational modifications, such as the phosphorylation of tyrosines, are often the initiation step for intracellular signaling cascades. Pan-reactive antibodies against modified amino acids (e.g., anti-phosphotyrosine), which are often used to ...
Nileena Velappan +10 more
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GAP activity, but not subcellular targeting, is required for Arabidopsis RanGAP cellular and developmental functions [PDF]
, 2015 The Ran GTPase activating protein (RanGAP) is important to Ran signaling involved in nucleocytoplasmic transport, spindle organization, and postmitotic nuclear assembly.
Boruc, Joanna +6 more
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