Results 31 to 40 of about 111,329,672 (189)
Homeostasis Imbalance of YY2 and YY1 Promotes Tumor Growth by Manipulating Ferroptosis
Advanced Science, 2022 Ferroptosis is a type of programmed cell death caused by disruption of redox homeostasis and is closely linked to amino acid metabolism. Yin Yang 2 (YY2) and its homolog Yin Yang 1 (YY1) are highly homologous, especially in their zinc‐finger domains ...
Yanjun Li +7 more
doaj +1 more source
Yin Yang 1 is a target of microRNA-34 family and contributes to gastric carcinogenesis [PDF]
, 2017 Gastric cancer is the second leading cause of cancer-related death worldwide. Herein, we investigated the role of transcription factor Yin Yang 1 (YY1), a multifunctional protein, in tumorigenesis of gastric cancer cells.
林敬哲 +1 more
core +2 more sources
Yin Yang 1 (YY1) synergizes with Smad7 to inhibit TGF-β signaling in the nucleus [PDF]
Science China Life Sciences, 2013 As a prototype of the TGF-β superfamily cytokines, TGF-β is well known for its diverse roles in embryogenesis and adult tissue homeostasis. TGF-β evokes cellular responses by signaling mainly through cell membrane receptors and transcription factor R-Smads and Co-Smad (Smad4), while an inhibitory Smad, Smad7, acts as a critical negative regulator of ...
Yan, XiaoHua +6 more
openaire +2 more sources
A Novel YY1-miR-1 regulatory circuit in skeletal myogenesis revealed by genome-wide prediction of YY1-miRNA network. [PDF]
PLoS ONE, 2012 microRNAs (miRNAs) are non-coding RNAs that regulate gene expression post-transcriptionally, and mounting evidence supports the prevalence and functional significance of their interplay with transcription factors (TFs).
Leina Lu +8 more
doaj +1 more source
International Journal of Genomics, 2022 Objective. To investigate the expression of Yin-Yang-1 (YY1) in esophageal carcinoma (ESCA) and its effect on glutamine metabolism in ESCA. Methods. The expression and roles of YY1 in ESCA were investigated using a series of bioinformatics databases and ...
Can Luo +8 more
doaj +1 more source
Neural Regeneration Research, 2019 Yin Yang 1 (YY1) is a multi-functional transcription factor that regulates gene expression in a range of cell types, including neurons. It controls neuronal differentiation, as well as neuronal specification and migration during the development of the ...
Zhefan Stephen Chen, Ho Yin Edwin Chan
doaj +1 more source
Growth hormone promotes hepatic gluconeogenesis by enhancing BTG2–YY1 signaling pathway
Scientific Reports, 2021 Growth hormone (GH) is one of the critical factors in maintaining glucose metabolism. B-cell translocation gene 2 (BTG2) and yin yang 1 (YY1) are key regulators of diverse metabolic processes.
Jeong-Rang Jo +4 more
doaj +1 more source
Yin Yang-1 inhibits tumor cell growth and inhibits p21(WAF1/Cip1) complex formation with Cdk4 and cyclin D1 [PDF]
, 2016 The GLI-Krüppel zinc finger factor yin yang-1 (YY1) is a complex protein that regulates a variety of processes including transcription, proliferation, development and differentiation. YY1 inhibits cell growth in a cell typespecific manner.
Parish, Christopher +5 more
core +1 more source
MedComm, 2022 Invasive cancer growth and metastasis account for the poor prognosis of high‐grade breast cancer. Recently, we reported that kinectin 1 (KTN1), a member of the kinesin‐binding protein family, promotes cell invasion of triple‐negative breast cancer and ...
Lin Gao +17 more
doaj +1 more source
Hubungan Gambaran Histopatologi Tuba Fallopi dengan Ekspresi mRNA p53 dan mRNA Yin-Yang 1 (YY1) pada Karsinoma Ovarium Musinosum [PDF]
, 2023 Latar belakang: Kanker ovarium merupakan kanker terbanyak ketiga di Indonesia setelah kanker payudara dan kanker leher rahim. Prevalensi karsinoma ovarium musinosum secara global paling sedikit daripada subtipe lainnya, namun frekuensi relatif subtipe ...
NOOR, Istikomah
core