Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo [PDF]
Toxins, 2019 Zearalenone (ZEN)-degrading enzymes are a promising strategy to counteract the negative effects of this mycotoxin in livestock. The reaction products of such enzymes need to be thoroughly characterized before technological application as a feed additive ...
Sebastian Fruhauf +11 more
doaj +2 more sources
Screening of Pig-Derived Zearalenone-Degrading Bacteria through the Zearalenone Challenge Model, and Their Degradation Characteristics [PDF]
Toxins, 2022 Zearalenone (ZEN) is widely found in food and feed. Its cytotoxicity, reproductive toxicity, genetic toxicity, immunotoxicity and hepatorenal toxicity have serious impacts on human and animal health.
Xue Yang +7 more
doaj +2 more sources
Controlled Production of Zearalenone-Glucopyranoside Standards with Cunninghamella Strains Using Sulphate-Depleted Media [PDF]
Toxins, 2021 In recent years, conjugated mycotoxins have gained increasing interest in food safety, as their hydrolysis in human and animal intestines leads to an increase in toxicity. For the production of zearalenone (ZEN) glycosides reference standards, we applied
Jeroen Peters +5 more
doaj +2 more sources
Kinetics and Distribution of Zearalenone-14-Glucoside and Its Metabolite Zearalenone in Rat, Determined by a Reliable HPLC-MS/MS Method [PDF]
Applied Sciences, 2023 A reliable high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established for the simultaneous detection of zearalenone-14-glucoside (ZEN-14G) and its metabolite, zearalenone (ZEN), in the plasma, urine, and various ...
Yaling Cai +7 more
doaj +2 more sources
CLICK-FLISA Based on Metal–Organic Frameworks for Simultaneous Detection of Fumonisin B1 (FB1) and Zearalenone (ZEN) in Maize [PDF]
BiosensorsMycotoxins are secondary products produced primarily by fungi and are pathogens of animals and cereals, not only affecting agriculture and the food industry but also causing great economic losses. The development of rapid and sensitive methods for the detection of mycotoxins in food is of great significance for livelihood issues. This study employed an
Jingyang Zhang +10 more
openaire +4 more sources
Occurrences of Deoxynivalenol, Zearalenone and some of their masked forms in selected cereals from Southwest Nigeria [PDF]
NFS Journal, 2021 The study determined the occurrence of deoxynivalenol (DON), zearalenone (ZEN) and their metabolites in staple cereals from Southwest Nigeria. Sixty composite samples of maize, sorghum and millet were evaluated for DON, ZEN and their masked forms; 3 ...
Bunmi K. Olopade +4 more
doaj +3 more sources
Solid Phase Extraction of Zearalenone (ZEN) from Beer Samples Using Natural Zeolite Clinoptilolite and Organo-Zeolites Prior to HPLC Determination [PDF]
Ekoloji, 2013 Zearalenone (ZEN), is a secondary metabolite with estrogenic properties, is produced by several Fusarium species that colonize cereal grains such as corn, oats, barley, wheat, and grain sorghum in the field and in storage. Because of the toxic effects of ZEN which cause significant human and animal diseases and significant economic losses worldwide ...
Pasınlı, Türker, Henden, Emür
core +4 more sources
Analytical approaches and preparation of biological, food and environmental samples for analyses of zearalenone and its metabolites [PDF]
Reviews in Analytical Chemistry, 2020 Zearalenone (ZEN) is a mycotoxin that occurs in all stages of plant growth and development and exerts harmful effects on humans and animals. Zearalenone is easily absorbed in the digestive tract, and it is metabolized in the intestinal wall and the liver.
Gadzała-Kopciuch Renata +2 more
doaj +2 more sources
Effects of a Multicomponent Mycotoxin Detoxifying Agent on Health and Performance of Weaned Pigs Under Combined Dietary Exposure to Deoxynivalenol (DON) and Zearalenone (ZEN) [PDF]
ToxinsThe aim of the present study was to evaluate the efficacy of a multicomponent mycotoxin detoxifying agent (MMDA, MYCORAID, Patent Co, Mišićevo, Serbia) in weaned pigs receiving contaminated feed with deoxynivalenol (DON) and zearalenone (ZEN). In total, 168 pigs were equally allocated in four experimental groups from day 25 to day 66 of age.
Jog Raj +5 more
openaire +4 more sources
Efficient Biotransformation of Zearalenone in Acidic Food Matrices by Alkaline Enzyme–Inorganic Hybrid Nanoflower [PDF]
ToxinsZearalenone (ZEN) is a pervasive mycotoxin contaminating global food and feed. While enzymatic degradation offers a promising, specific, and eco-friendly strategy for mycotoxin mitigation, the biotransformation of ZEN within acidic food matrices remains ...
Ping Ding +5 more
doaj +2 more sources