Evaluation of Activity of Pro- and Anti-Inflammatory Mediators and Nitrosative Stress in Liver Tissue of Wild Boars (Sus scrofa) Positive for Zearalenone (ZEN) Contamination in Campania Region, Southern Italy [PDF]
ToxinsZearalenone (ZEN) is a mycotoxin commonly produced by Fusarium species and is often found in food and feed. It has been linked to reproductive problems in livestock and, less frequently, to hyperestrogenic effects in humans. However, information regarding the impact of ZEN on wild boars (Sus scrofa) remains scarce, despite this species being among the ...
Sara Damiano +9 more
openaire +5 more sources
Laccase-Mimicking Cu-Tannic Acid Nanozyme for Zearalenone Detoxification: Mechanism and Application in Corn Oil [PDF]
FoodsZearalenone (ZEN), a prevalent estrogenic mycotoxin found in grains and oils, poses significant health risks due to its endocrine-disrupting properties. This study elucidates the application of a laccase-mimicking copper-tannic acid (CuTA) nanozyme as an
Hongfei Li +6 more
doaj +2 more sources
A method for estimating the outer exposure of dairy cows to deoxynivalenol (DON) and zearalenone (ZEN) as a precondition for risk assessment based on inner exposure with toxin residue levels in blood and urine as indicators [PDF]
Mycotoxin ResearchAbstractDON and ZEN residues in the blood and urine of dairy cows can be used to predict the outer exposure to DON and ZEN expressed per kilogram diet for a risk evaluation based on comparisons to critical dietary concentrations. This method was used to evaluate the exposure of dairy cows from 12 farms located in Brandenburg, Germany, fed rations with ...
Sven Dänicke +13 more
openaire +5 more sources
Removal of Zearalenone from Degummed Corn Oil by Hydrolase on a Batch-Refining Unit [PDF]
Foods, 2022 The removal of zearalenone (ZEN) from degummed corn oil (DCO) using hydrolase on a batch-refining unit was studied. According to single-factor and response surface experiments, the optimum technological conditions for reaching the maximum degradation ...
Chenwei Zhao +4 more
doaj +2 more sources
Zearalenone Exposure Disrupts STAT-ISG15 in Rat Colon: A Potential Linkage between Zearalenone and Inflammatory Bowel Disease [PDF]
Toxins, 2023 Zearalenone (ZEN), a prevalent mycotoxin contaminating food and known for its intestinal toxicity, has been suggested as a potential risk factor for inflammatory bowel disease (IBD), although the exact relationship between ZEN exposure and IBD remains ...
Haonan Ruan +7 more
doaj +2 more sources
Zearalenone Biotransformation by Tibetan Plateau-Derived Yeast Hannaella zeae: Biological Pattern Elucidation, Metabolite Safety, and Environmental Tolerance [PDF]
ToxinsZearalenone (ZEN) poses serious risks to human and animal health. Compared with physical and chemical methods, microbial transformation offers a safer and more sustainable strategy for ZEN detoxification.
Chenxiaoye Yang +11 more
doaj +2 more sources
The Protective Role of Bacillus velezensis A2 on the Biochemical and Hepatic Toxicity of Zearalenone in Mice [PDF]
Toxins, 2018 Zearalenone (ZEN) is an estrogen-like mycotoxin produced by Fusarium that seriously compromises the safety of animal and human health. In this study, our aim was to evaluate the protective effect of Bacillus velezensis A2 against biochemical and ...
Nan Wang +7 more
doaj +2 more sources
In Vitro Reduction of Extractable Zearalenone and Screening of Tentative Transformation Products by Metschnikowia pulcherrima KKP 1368 Under Selected Buffered pH Conditions Relevant to the Porcine Gastrointestinal Tract [PDF]
ToxinsZearalenone (ZEN) is an estrogenic mycotoxin produced by Fusarium spp. and commonly found in cereals and feed materials. This study evaluated the ability of Metschnikowia pulcherrima KKP 1368 biomass to reduce extractable ZEN under controlled buffered pH
Krzysztof Waśkiewicz +4 more
doaj +2 more sources
Development of a reliable UHPLC-MS/MS method for simultaneous determination of zearalenone and zearalenone-14-glucoside in various feed products [PDF]
Frontiers in Chemistry, 2022 A reliable ultra-high-performance liquid chromatography–tandem mass spectrometry method (UHPLC-MS/MS) was developed for the simultaneous determination of two mycotoxins, that is, zearalenone (ZEN) and zearalenone-14-glucoside (ZEN-14G) in formula feed ...
Zhiqi Zhang +8 more
doaj +2 more sources
mRNA Expression of Two Colon Enzymes in Pre-Pubertal Gilts During a 42-Day Exposure to Zearalenone [PDF]
ToxinsThe aim of this study was to determine whether a low dose of zearalenone (ZEN) affects the mRNA expression of the CYP1A1 (P450 cytochrome) and GSTπ1 (glutathione S-transferase) genes in the large intestine of pre-pubertal gilts.
Magdalena Gajęcka +2 more
doaj +2 more sources