Results 101 to 110 of about 27,806 (225)

Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems [PDF]

, 2003
Serine proteases, cysteine proteases, and matrix metalloproteinases (MMPs) are involved in cancer cell invasion and metastasis. Recently, a recombinant bifunctional inhibitor (chCysuPA(19-31)) directed against cysteine proteases and the urokinasetype ...
Brew K., Kitts P.A., Kos J., Kotzsch M., Lah T.T., Magdolen U., Possee R.D., Rabbani S.A., Reuning U., Stetler-Stevenson W.G., Szpaderska A.M., Thomas C.J.   +11 more
core   +2 more sources

Deteksi Aktivitas Fibrinolitik Isolat Bakteri WU 021055* Asal Perairan Pantai Papuma Jember Menggunakan Zimografi

Global Medical & Health Communication, 2017
Abstrak Bakteri merupakan sumber penting berbagai enzim termasuk enzim fibrinolitik. Enzim ini diperlukan untuk mendegradasi bekuan darah pada orang yang mengalami penyakit trombosis.
Evi Umayah Ulfa, Esti Utarti, Izzay Afkarina, Sattya Arimurti, Kartika Senjarini   +4 more
doaj  

A FAST AND SENSITIVE ZYMOGRAPHY METHOD OF PEROXIDASE ACTIVITY DETERMINATION USING SODIUM ACETATE BUFFER

Studia Universitatis Babes-Bolyai Chemia, 2019
By changing the buffer composition from phosphate to acetate (in both cases, the pH value was 6.0), the sensitivity of the estimation of peroxidase activity in polyacrylamide gels was improved from 4 µg/well to 0.4 µg/well.
Gheorghița MENGHIU, Amalia Nicoleta IANCU, Vasile OSTAFE   +2 more
doaj   +1 more source

Neuroprotection by minocycline in murine traumatic spinal cord injury: analyses of matrix metalloproteinases [PDF]

, 2017
Aim: Minocycline has neuroprotective activities in several models of neurological disorders including spinal cord injury (SCI) where it prevents axonal loss and improves functional recovery.
Casha, Steven, Edwards, Dylan, Hurlbert, John, Larsen, Jennifer E.A., Larsen, Peter H., Li, Hui, Nuttall, Robert K., Rice, Tiffany, Yong, V. Wee   +8 more
core   +1 more source

Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure [PDF]

, 2015
Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR).
Ampe, Christophe, Bogaerts, Eliene, Descamps, Benedicte, Devisscher, Lindsey, Geerts, Anja, Govaere, O, Laukens, Debby, Libbrecht, Louis, Paridaens, Annelies, Raevens, Sarah, Van den Bussche, A, Van Steenkiste, Christophe, Van Troys, Marleen, Van Vlierberghe, Hans, Vandewynckel, Yves-Paul, Vanhove, Christian, Verhelst, Xavier   +16 more
core   +3 more sources

Ex vivo Follicle Rupture and in situ Zymography in Drosophila

Bio-Protocol, 2018
Ovulation, the process of releasing a mature oocyte from the ovary, is crucial for animal reproduction. In order for the process of ovulation to occur, a follicle must be fully matured and signaled to rupture from the ovary.
Elizabeth Knapp, Lylah Deady, Jianjun Sun   +2 more
doaj   +1 more source

Collagenolytic Activity Is Associated with Scar Resolution in Zebrafish Hearts after Cryoinjury

Journal of Cardiovascular Development and Disease, 2017
Myocardial infarction is the major cause of cardiac injury in western countries and can result in a massive loss of heart cells, leading eventually to heart failure.
Laurent Gamba, Armaan Amin-Javaheri, Jieun Kim, David Warburton, Ching-Ling Lien   +4 more
doaj   +1 more source

Zymography of proteases in honey bees (Apis Mellifera) infected with Nosema ceranae [PDF]

Veterinarski Glasnik
Nosemosis is one of the most important honey bee diseases and is caused by two fungal species of the genus Nosema, i.e., Nosema apis and Nosema ceranae.
Doghuzlu Mohammad Afrasiabi, Nabian Sedigheh, Paghaleh Gholam Ali Nehzati, Taheri Mohammad, Asadollahi Zahra, Akhzari Soheila   +5 more
doaj   +1 more source

A Targeted Quantitative Proteomic Method Revealed a Substantial Reprogramming of Kinome during Melanoma Metastasis. [PDF]

, 2020
Kinases are involved in numerous critical cell signaling processes, and dysregulation in kinase signaling is implicated in many types of human cancers.
Guo, Lei, Huang, Ming, Li, Lin, Liu, Xiaochuan, Miao, Weili, Qi, Tianyu F, Wang, Yinsheng   +6 more
core   +1 more source

Combined in Situ Zymography, Immunofluorescence, and Staining of Iron Oxide Particles in Paraffin-Embedded, Zinc-Fixed Tissue Sections

Molecular Imaging, 2012
Superparamagnetic iron oxide particles are used as potent contrast agents in magnetic resonance imaging. In histology, these particles are frequently visualized by Prussian blue iron staining of aldehyde-fixed, paraffin-embedded tissues.
Eyk Schellenberger, Akvile Haeckel, Lena Schoenzart, Franziska Appler, Joerg Schnorr, Matthias Taupitz, Bernd Hamm   +6 more
doaj   +1 more source