Results 71 to 80 of about 1,350 (124)

α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. [PDF]

Br J Pharmacol, 2018
Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ.   +4 more
europepmc   +1 more source

Prediction of Specificity of α-Conotoxins to Subtypes of Human Nicotinic Acetylcholine Receptors with Semi-supervised Machine Learning. [PDF]

ACS Chem Neurosci
Do HN, Kubicek-Sutherland JZ, Gnanakaran S.   +2 more
europepmc   +1 more source

Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus. [PDF]

Toxins (Basel), 2018
Giribaldi J, Wilson D, Nicke A, El Hamdaoui Y, Laconde G, Faucherre A, Moha Ou Maati H, Daly NL, Enjalbal C, Dutertre S.   +9 more
europepmc   +1 more source

An N-Terminally Elongated Peptide From Conus rolani Defines a New Class of Ribbon α-Conotoxins Targeting Muscle nAChRs. [PDF]

FASEB J
Giglio ML, Flórez-Salcedo P, Azam L, Watkins M, Koch TL, Basgall-De la Rosa E, Douglass AD, McIntosh JM, Olivera BM, Gajewiak J.   +9 more
europepmc   +1 more source

Role of Cys_I-Cys_III Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors. [PDF]

ACS Omega, 2017
Tabassum N, Tae HS, Jia X, Kaas Q, Jiang T, Adams DJ, Yu R.   +6 more
europepmc   +1 more source

Computational Design of α-Conotoxins to Target Specific Nicotinic Acetylcholine Receptor Subtypes. [PDF]

Chemistry
Wu X, Hone AJ, Huang YH, Clark RJ, McIntosh JM, Kaas Q, Craik DJ.   +6 more
europepmc   +1 more source

Editorial: From Peptide and Protein Toxins to Ion Channel Structure/Function and Drug Design

Frontiers in Pharmacology, 2020
Annette Nicke, Chris Ulens, Jean-Francois Rolland, Victor I. Tsetlin   +3 more
doaj   +1 more source

Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. [PDF]

J Biol Chem, 2016
Cuny H, Kompella SN, Tae HS, Yu R, Adams DJ.   +4 more
europepmc   +1 more source

α-Conotoxins Identify the α3β4* Subtype as the Predominant Nicotinic Acetylcholine Receptor Expressed in Human Adrenal Chromaffin Cells. [PDF]

Mol Pharmacol, 2015
Hone AJ, McIntosh JM, Azam L, Lindstrom J, Lucero L, Whiteaker P, Passas J, Blázquez J, Albillos A.   +8 more
europepmc   +1 more source

Inhibition of cholinergic pathways in Drosophila melanogaster by α-conotoxins.

FASEB J, 2015
Heghinian MD, Mejia M, Adams DJ, Godenschwege TA, Marí F.   +4 more
europepmc   +1 more source