Results 21 to 30 of about 12,529 (184)

An L213A variant of β-glycosidase from Sulfolobus solfataricus with increased α-L-arabinofuranosidase activity converts ginsenoside Rc to compound K.

open access: yesPLoS ONE, 2018
Compound K (C-K) is a crucial pharmaceutical and cosmetic component because of disease prevention and skin anti-aging effects. For industrial application of this active compound, the protopanaxadiol (PPD)-type ginsenosides should be transformed to C-K. β-
Ji-Hyeon Choi   +2 more
doaj   +1 more source

Anticholinergic and antidiabetic effects of isoeugenol from clove (Eugenia caryophylata) oil

open access: yesInternational Journal of Food Properties, 2019
Isoeugenol (2-methoxy-4-(prop-1-en-1-yl)phenol), a component of from clove (Eugenia caryophylata) oil, is a starting material for both the biotechnological and synthetic production of vanillin and vanillic acid.
Fevzi Topal
doaj   +1 more source

3-Hydroxypyrrolidine and (3,4)-dihydroxypyrrolidine derivatives: inhibition of rat intestinal α-glucosidase [PDF]

open access: yes, 2014
Thirteen pyrrolidine-based iminosugar derivatives have been synthesized and evaluated for inhibition of α-glucosidase from rat intestine. The compounds studied were the non-hydroxy, mono-hydroxy and dihydroxypyrrolidines.
Adriano, Gizé   +8 more
core   +1 more source

Pasta fortified with C-glycosides-rich carob (Ceratonia siliqua L.) seed germ flour: Inhibitory activity against carbohydrate digesting enzymes [PDF]

open access: yes, 2023
Carob (Ceratonia siliqua L.) seed germ flour (SGF) is a by-product resulting from the extractionextraction of locust bean gum (E410), which is a texturing and thickening ingredient used for food, pharmaceutical and cosmetic preparations. SGF is a protein-
Mamone, Gianfranco   +4 more
core   +1 more source

Oleanolic acid (pentacyclic triterpenes) as a potential candidate for α-glycosidase inhibition activity [PDF]

open access: yes, 2022
Background: Diabetes mellitus is a common health dilemma worldwide and is characterized by hyperglycemia. Inhibition in the activity of one of the digestive tract enzymes α-glucosidase is one of the therapeutic approaches to hydrolyze carbohydrates into ...
Javaid, Iqra   +3 more
core   +2 more sources

The inhibition profile of sesamol against α-glycosidase and acetylcholinesterase enzymes

open access: yesInternational Journal of Food Properties, 2019
Sesamol (1,3-benzodioxol-5-ol) is found in the oilseed product, sesame. In our study, the inhibitory effects of sesamol compound on acetylcholinesterase and α-glycosidase enzymes were evaluated.
Meryem Topal
doaj   +1 more source

Antioxidant activity and antidiabetic activities of Northern Thai indigenous edible plant extracts and their phytochemical constituents

open access: yesHeliyon, 2022
Diabetes mellitus is the most common non-infective disease characterized by hyperglycemia (high level of blood glucose). Formation of advanced glycation end products (AGEs) in long termed-hyperglycemia and oxidative stress are the key factors to ...
Plaipol Dedvisitsakul   +1 more
doaj   +1 more source

Generation of Molecular Complexity from Cyclooctatetraene: Preparation of Aminobicyclo[5.1.0]octitols [PDF]

open access: yes, 2015
A series of eight stereoisomeric N-(tetrahydroxy bicyclo-[5.1.0]oct-2S*-yl)phthalimides were prepared in one to four steps from N-(bicyclo[5.1.0]octa-3,5-dien-2-yl)phthalimide (±)-7, which is readily available from cyclooctatetraene (62 % yield).
Donaldson, William   +5 more
core   +2 more sources

Rosemary Extract as a Potential Anti-Hyperglycemic Agent: Current Evidence and Future Perspectives [PDF]

open access: yes, 2017
Type 2 diabetes mellitus (T2DM), a disease on the rise and with huge economic burden to health care systems around the globe, results from defects in insulin action (termed insulin resistance) combined with impaired insulin secretion.
Naimi, Madina   +3 more
core   +2 more sources

Examining the antioxidant capabilities and enzyme-inhibiting potentials of the Stachys bombycina Boiss extracts. [PDF]

open access: yes, 2021
Scope and Context: Roughly 300 species of Stachys L. are known to exist throughout the globe. Across Turkey, especially in the south and east, you may find more than 120 different taxa, with about 60 of them being endemic.
Momina , Fathima   +2 more
core   +2 more sources

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