Results 131 to 140 of about 34,901 (267)

OXA-1 β-lactamase and non-susceptibility to penicillin/β-lactamase inhibitor combinations among ESBL-producing Escherichia coli [PDF]

, 2018
Background ESBL-producing Escherichia coli have expanded globally since the turn of the century and present a major public health issue. Their in vitro susceptibility to penicillin/inhibitor combinations is variable, and clinical use of these ...
Cleary, Paul, Day, Michaela, Doumith, Michel, Hopkins, Katie L, Livermore, David M, Toleman, Mark A, Wareham, David W, Wiuff, Camilla, Woodford, Neil   +8 more
core   +3 more sources

NCY‐1 β‐Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica

MicrobiologyOpen, Volume 15, Issue 2, April 2026.
This study shows a strong correlation between the β‐lactam susceptibility profile of a clinical isolate of Nocardia cyriacigeorgica and the activity of its β‐lactamase, NCY‐1. Inhibitors of NCY‐1 reduce the minimum inhibitory concentration of amoxicillin.
Julie Couston, Athénaïs Le Marchand, Elisabeth Hodille, Charlotte Genestet, Brune Joannard, Jérôme Feuillard, Yvonne Benito, Oana Dumitrescu, Mickaël Blaise   +8 more
wiley   +1 more source

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2962-2977, April 2026.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi, Xin Liu, Nan Wang, Qianwen Zhang, Jianjun Gao, Canghai Guan, Yapeng Li, Chengru Yang, Shaowu Bi, Xinlei Zou, Xiangyu Zhong   +10 more
wiley   +1 more source

Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]

, 2017
In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De, Mascellino, Maria Teresa, Oliva, Alessandra   +2 more
core   +1 more source

Discriminatory Detection of Inhibitor-Resistant β-Lactamases in Escherichia coli by Single-Strand Conformation Polymorphism-PCR [PDF]

, 1998
Valérie Speldooren, Béate Heym, Roger Labia, Marie-Hélène Nicolas-Chanoine   +3 more
openalex   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

Étude du potentiel synergique des mutations de résistance aux inhibiteurs de la β-lactamase blac de mycobacterium tuberculosis [PDF]

, 2014
La résistance bactérienne aux antibiotiques de type β-lactame est un problème majeur menaçant le succès des traitements contre les maladies infectieuses à travers le monde.
Egesborg, Philippe
core  

Use of Novel Antibiograms to Determine the Need for Earlier Susceptibility Testing and Administration for New β-Lactam/β-Lactamase Inhibitors in the United States [PDF]

, 2022
Kenneth Klinker, Levita Hidayat, Eric Wenzler, Joan-Miquel Balada-Llasat, Mary Motyl, C Andrew DeRyke, Karri A. Bauer   +6 more
openalex   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, Volume 13, Issue 14, 9 March 2026.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source