Results 151 to 160 of about 34,901 (267)

Engineered Probiotics: The Next‐Generation Therapeutics to Combat Antibiotic‐Resistant Bacterial Infections

Food Frontiers, Volume 7, Issue 2, March 2026.
Engineered probiotics secretes fusion proteins which potentially neutralized the toxins secreted by other microbial communities. ABSTRACT On a global scale, the escalating burden of infectious diseases, predominantly attributed to bacterial pathogens, especially drug‐resistant strains, has progressed into a critical concern for clinical management and ...
Indu Singh, Raz Abdulqadir, Indira Kumari Verma, Yashika Awasthi, Arun Ratn, Juhi Sharma, Manmeet Rawat, Megh Singh Dhakad, Jasbir Dalal, Yash Gupta, Bhisham Narayan Singh, Divakar Sharma   +11 more
wiley   +1 more source

Comprehensive screening of potential inhibitors from ZINC15 database for Metallo-L1 Β -Lactamase from Stenotrophomonas maltophilia via in Silico and in vitro approaches

BMC Microbiology
Background Antibiotic resistance caused by pathogenic microbes have become a serious issue in health field as most of the antibiotics discovered are rendered ineffective for the treatment of numerous microbial infections.
K H Sreenithya, Salim Manoharadas, Shobana Sugumar   +2 more
doaj   +1 more source

Meropenem/vaborbactam: a next generation β-lactam β-lactamase inhibitor combination [PDF]

, 2020
Andrea Novelli, Paola Del Giacomo, Gian María Rossolini, Mario Tumbarello   +3 more
openalex   +1 more source

Bacterial Profiling and Antibiotic Resistance Pattern of Uropathogens Isolated From Adolescent Girls With Bacteriuria: A Cross‐Sectional Study

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aims Urinary tract infections (UTIs) are prevalent among adolescent girls. Therefore, effective promotional campaigns are crucial for conveying accurate information. This study aimed to assess the prevalence and the antimicrobial profiling of the isolated uropathogens among 354 adolescent girls. Methods This is a cross‐sectional
Shimaa Abdelrahim Khalaf, Mona Gamal Mohamed, Amal A. Elkhawaga, Iftekhar Ahmed, Md. Rabiul Islam, Shaimaa M. Goda   +5 more
wiley   +1 more source

Divalent Metal Binding Properties of the Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 2000
The metal-binding properties of the methionyl aminopeptidase from Escherichia coli (MetAP) were investigated. Measurements of catalytic activity as a function of added Co(II) and Fe(II) revealed that maximal enzymatic activity is observed after the ...
Bennett, Brian, Copik, Alicja J., D\u27Souza, Ventris M., Holz, Richard C.   +3 more
core   +1 more source

Synthesis of novel ciprofloxacin-avibactam conjugates for the development of second-generation non-β-lactam-β-lactamase inhibitors

, 2023
Rahul Kumar, Vikas Pathania, Shashi Kumar, M. Vignesh Kumar, Hemraj Nandanwar, Sushil K. Maurya   +5 more
openalex   +1 more source

New β-Lactamase Inhibitors: a Therapeutic Renaissance in an MDR World [PDF]

, 2013
Sarah M. Drawz, Krisztina M. Papp‐Wallace, Robert A. Bonomo   +2 more
openalex   +1 more source

Evolutionary Trajectories toward High-Level β-Lactam/β-Lactamase Inhibitor Resistance in the Presence of Multiple β-Lactamases

, 2022
Fredrika Rajer, Lisa Allander, Philip A. Karlsson, Linus Sandegren   +3 more
openalex   +2 more sources

Evaluation of the Potential Carrier and Controlled Release of Antibiotics by Zinc, Nickel, and Cobalt Ferrite Nanoparticles Encapsulated with Silica and Functionalized with Moxifloxacin Hydrochloride

Particle &Particle Systems Characterization, Volume 43, Issue 3, March 2026.
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu, Stéfanne R. R. Ferreira, Naiara G. Cabral, Romayne P. França, Hanstter H. A. Rezende, Richard Landers, Alexandre Pancotti   +6 more
wiley   +1 more source

Resistance of Gram-Negative Bacteria to Cefepime-Enmetazobactam: A Systematic Review

Pathogens
Cefepime-enmetazobactam is a novel β-lactam/β-lactamase inhibitor combination showing good activity against multidrug-resistant (MDR) Gram-negative bacteria producing a variety of β-lactamases.
Matthew E. Falagas, Laura T. Romanos, Dimitrios S. Kontogiannis, Katerina Tsiara, Stylianos A. Kakoullis   +4 more
doaj   +1 more source