Results 111 to 120 of about 14,756 (172)

Repurposing Drugs as Bacteroides fragilis BFT‐3 Inhibitors in the Animal Infection Model Galleria mellonella

Annals of the New York Academy of Sciences, Volume 1557, Issue 1, March 2026.
This work establishes a newly developed Galleria mellonella infection model as a powerful, ethical platform for studying Bacteroides fragilis pathogenesis and therapy. Leveraging this model, the study identifies MOA4 as a potent BFT‐3 inhibitor that improves host survival, increases bacterial clearance, and synergizes with antibiotics without toxicity.
Ana Jiménez‐Alesanco, Marta Gómara‐Lomero, Hajar Jeblaoui, Sonia Vega, Adrián Velázquez‐Campoy, José Antonio Aínsa, Olga Abián   +6 more
wiley   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

Reviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula, Yuri Duarte Porto, Vinícius Silva Castro, Érica do Carmo Dias Matos, Adelino Cunha‐Neto, Ricardo César Tavares Carvalho, Luciana Kimie Savay‐da‐Silva, Eduardo Eustáquio de Souza Figueiredo, Tathiana Ferguson Motheo   +8 more
wiley   +1 more source

In vitro activity of new combinations of β-lactam and β-lactamase inhibitors against the Mycobacterium tuberculosis complex. [PDF]

Microbiol Spectr, 2023
Economou Lundeberg E, Andersson V, Wijkander M, Groenheit R, Mansjö M, Werngren J, Cortes T, Barilar I, Niemann S, Merker M, Köser CU, Davies Forsman L.   +11 more
europepmc   +1 more source

Design, Synthesis, and Evaluation of β‑Lactamase Inhibitors as Potential Therapeutics for Antimicrobial Resistance. [PDF]

ACS Omega
Batool S, Farid R, Azam SS, Hassan A.
europepmc   +1 more source

In vitro and in vivo evaluation of two combined β-lactamase inhibitors against carbapenem-resistant Acinetobacter baumannii. [PDF]

Eur J Clin Microbiol Infect Dis, 2023
Domínguez AV, Panadero IM, Smani Y.
europepmc   +1 more source

Polyphenols as Potential β-Lactamase Inhibitors: An Integrated Computational and Experimental Study. [PDF]

Molecules
Mourabiti F, Jouga F, Calvo LG, Villarino RA, Zouheir Y, Soukri A, de Miguel T, El Khalfi B.   +7 more
europepmc   +1 more source

Carbapenems versus β-lactam and β-lactamase inhibitors for treatment of nosocomial pneumonia: A systematic review and meta-analysis. [PDF]

Heliyon, 2023
Cang HQ, Quan XH, Chu XH, Liang Y, Yang X, Li J.   +5 more
europepmc   +1 more source

Comparative analysis of the effects of aztreonam combined with four β-lactamase inhibitors against carbapenem-resistant <i>Enterobacterales</i>. [PDF]

Microbiol Spectr
Meng Q, Xu C, Li W, Shen K, Huang X, Fu X, Zhou L, Chen Y, Hu F, Wang H.   +9 more
europepmc   +1 more source

Integrating Siderophore Substructures in Thiol-Based Metallo-β-Lactamase Inhibitors. [PDF]

Molecules, 2023
Rotter MJ, Zentgraf S, Weizel L, Frank D, Burgers LD, Brunst S, Fürst R, Proschak A, Wichelhaus TA, Proschak E.   +9 more
europepmc   +1 more source

Synthesis and biological evaluation of novel β-lactam-metallo β-lactamase inhibitors. [PDF]

RSC Adv, 2023
Shungube M, Hlophe AK, Girdhari L, Sabe VT, Peters BB, Reddy N, Omolabi KF, Chetty L, Arumugam T, Chuturgoon A, Kruger HG, Arvidsson PI, Qin HL, Naicker T, Govender T.   +14 more
europepmc   +1 more source