Results 111 to 120 of about 1,471,936 (197)

Measuring the capacity of yeast for surface display of cell wall‐anchored protein isoforms by using β‐lactamase as a reporter enzyme

FEBS Open Bio
Yeast surface display is a promising biotechnological tool that uses genetically modified yeast cell wall proteins as anchors for enzymes of interest, thereby transforming yeast cell wall into a living catalytic material. Here, we present a comprehensive
Tea Martinić Cezar, Antonia Paić, Stefani Prekpalaj, Renata Teparić, Bojan Žunar, Igor Stuparević   +5 more
doaj   +1 more source

Genetic Diversity and Epidemiological Overlap of Staphylococcus aureus at the Animal–Food–Environment–Human Interface Within a One Health Framework

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Integrating farm‐to‐fork and clinical surveillance, this study reveals distinct SCCmec distributions alongside shared spa types across human, animal, and food interfaces. The results of genetic diversity and epidemiological overlap underscore the critical need for coordinated One Health surveillance to monitor multi‐sectoral Staphylococcus aureus ...
Pinar Sagiroglu, Dursun Alp Gundog, Candan Gungor, Kursat Koskeroglu, Mustafa Altay Atalay, Adalet Dishan, Yeliz Ucar, Aytac Akcay, Huseyin Burak Disli, Harun Hizlisoy, Mukaddes Barel, Tekin Kececi, Nurhan Ertas Onmaz   +12 more
wiley   +1 more source

Antibiotic Resistance and Biofilm‐Forming Capacity of Oral Biofilm Bacteria in Patients With Periodontitis and Healthy Individuals

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Key finding: Antimicrobial resistance was common across all groups and associated with biofilm‐forming capacity, an association that remains observational and species‐confounded. ABSTRACT This study aimed to analyse antimicrobial resistance (AMR) in bacterial isolates from subgingival biofilms of patients with periodontitis and supragingival biofilms ...
Nils Werner, Marie Schöffel, Annette Wittmer, Klaus Pelz, Kirstin Vach, Cornelia Frese, Christiane von Ohle, Diana Wolff, Fabian Cieplik, Ali Al‐Ahmad   +9 more
wiley   +1 more source

Empirical Meropenem Versus Piperacillin/Tazobactam for Critically Ill Adults With Sepsis: Feasibility of a Randomised Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background Meropenem and piperacillin/tazobactam are commonly used empirical antibiotics in critically ill adults with sepsis, but whether one is superior to the other is uncertain. Methods The Empirical Meropenem versus Piperacillin/Tazobactam for Adult Patients with Sepsis (EMPRESS) trial is an ongoing investigator‐initiated, randomised ...
Nick Frørup Meier, Morten Hylander Møller, Maj‐Brit Nørregaard Kjær, Fredrik Sjövall, Marie Warrer Munch, Benjamin Skov Kaas‐Hansen, Hans‐Christian Thorsen‐Meyer, Bodil Steen Rasmussen, Marie Helleberg, Frederik Boëtius Hertz, Theis Lange, Aksel Karl Georg Jensen, Lars Wiuff Andersen, Jakob Steen Andersen, Jens Michelsen, Lars Peter Kloster Andersen, Morten Heiberg Bestle, Anne Craveiro Brøchner, Theis Skovsgaard Itenov, Steffen Christensen, Ronni Thermann Reitz Plovsing, Klaus Ulrik Koch, Anders Møller, Olav Lilleholt Schjørring, Naia Bech Cranø, Kasper Vamdrup‐Andersen, Davide Placido, Tine Sylvest Meyhoff, Carl Thomas Anthon, Aske Tøgern, Milda Grigonyte‐Daraskeviciene, Zemira Engbakken, Anne Witte Kamstrup, Kis Rønn Uhre, Jehad Ahmad Barakji, Rikke Faebo Larsen, Anders Perner, Anders Granholm   +37 more
wiley   +1 more source

Genetic and biochemical characterization of OXA-1054, a carbapenem-hydrolyzing class D β-lactamase conferring broad-spectrum β-lactam resistance in Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy
We aimed to characterize OXA-1054, a novel carbapenem-hydrolyzing class D β-lactamase (CHDL) detected in a multidrug-resistant Pseudomonas aeruginosa clinical isolate.
Lucía González-Pinto, Laura Monge-Olivares, Gloria Pérez-Rodríguez, Pablo Aja-Macaya, Lucía Sánchez-Peña, María Antonia Gomis-Font, Salud Rodríguez-Pallares, Tania Blanco-Martín, Lorena López-Cerero, Alejandro Beceiro, Pierre Bogaerts, Antonio Oliver, Germán Bou, Jorge Arca-Suárez   +13 more
doaj   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, Volume 101, Issue 10, Page 2672-2676, October 2026.
Elisa Buzzatti, Irene Terrenato, Martina Tomassi, Federica Lessi, Sara Pezone, Cristina Papayannidis, Gianluca Martini, Fabio Forghieri, Luana Fianchi, Martina Quattrone, Nicola Fracchiolla, Claudio Fozza, Michela Abbenante, Anna Lina Piccioni, Davide Facchinelli, Claudia Maria Basilico, Caterina Buquicchio, Nicola Di Renzo, Monica Piedimonte, Maria Giovanna Cefalo, Daniele Armiento, Adriano Venditti, Alessandro Busca, Francesco Marchesi, Maria Ilaria Del Principe, Livio Pagano   +25 more
wiley   +1 more source

Sodium deoxycholate synergistically enhances the antimicrobial activity of β-lactam antibiotics againstβ-lactamase-producing Staphylococcus aureus [PDF]

, 2012
Background β-lactamase-producing Staphylococcus aureus synthesizes a β-lactamase which decomposes the β-lactam ring, and consequently almost all β-lactam antibiotics are inactivated by the enzyme. The appearance of β-lactamase-producing bacterial strains
Yamada, Akira, Yoshida, Sayuri, Yaegashi, Asaka, Fujii, Yuichi, Hirano, Kano, Nozawa, Koohei, Tanaka, Satomi, Yamaki, Fumiko, Horie, Hitoshi   +8 more
core  

Synthesis, Characterization, and Multifunctional Bioactivity of ZnO/CuO@Amoxicillin Nanocomposites: A Synergistic Nano‐Platform With Potent Antioxidant, Anti‐Inflammatory, Antidiabetic, and Anti‐Cholinesterase Activities

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
ZnO/CuO@amoxicillin nanocomposite, synthesized via sol–gel route, demonstrates exceptional multifunctional performance. It strongly inhibits α‐amylase and α‐glucosidase, effectively suppresses inflammation, and exhibits superior antioxidant activity surpassing ascorbic acid.
Hocine Sadam Nesrat, Abdelatif Aouadi, Ibtissam Laib, Salah Eddine Laouini, Abderrhmane Bouafia, Djamila Hamada Saoud, Halima Zidane, Hafidha Terea, Mahmood M. S. Abdullah, Tomasz Trzepieciński, Dalila Saidane‐Mosbahi   +10 more
wiley   +1 more source

Fungal Antimicrobial Resistance: Mechanisms, Drivers, and Global Clinical Burden

ChemFoodChem, Volume 2, Issue 3, September 2026.
ABSTRACT Fungal antimicrobial resistance (AMR) is a growing concern for world health caused by an increase in multidrug‐resistant infections, an increase in environmental reservoirs, and the ineffectiveness of current antifungal treatments. Fungal infections continue to be largely excluded from AMR initiatives while causing over 1.6 million deaths ...
Bikash Baral
wiley   +1 more source

Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity‐Switching, Self‐Immobilizing, Near‐Infrared Fluorogenic β‐Lactamase Probe Enriched within Bacteria

Advanced Science
The emergence of antibiotic resistance, particularly bacterial resistance to β‐lactam antibiotics, the most widely prescribed therapeutic agents for infectious diseases, poses a significant threat to public health worldwide.
Fangfang Chen, Yuyao Li, Yan Peng, Yifan Zhu, Gao He, Zhengwei Zhang, Hexin Xie   +6 more
doaj   +1 more source