Derivatives of grindelic acid: from a non-active natural diterpene to synthetic antitumor derivatives [PDF]
, 2013 Using several reactions that include homologations and asymmetric epoxidations as well as Ugi and Huisgen couplings, we generated a small focused library of new derivatives from the labdane-type diterpene grindelic acid. These compounds were evaluated as
Chiaramello, Alejandra Ilda +7 more
core +3 more sources
Small Methods, EarlyView.Cardenolide‐functionalized extracellular vesicles enable targeted delivery of the chemotherapeutic doxorubicin to A549 lung cancer cells by binding Na+/K+‐ATPase, which is overexpressed in these cells. Surface‐modified, drug‐loaded EVs exhibit enhanced cytotoxicity compared to unmodified EVs and free drug, suggesting this system may lower the effective
Maja Dorfner +7 more
wiley +1 more source
Ligand synthesis catalyst and complex metal ion: multicomponent synthesis of 1,3-bis(4-phenyl-[1,2,3]triazol-1-yl)-propan-2-ol copper(i) complex and application in copper-catalyzed alkyne-azide cycloaddition [PDF]
, 2016 A new bistriazole copper complex was synthesized by direct treatment of an alkyne, an azide, and CuI as copper salt through in situ ligand formation under a multicomponent reaction process. This complex was analyzed by XPS, TGA, DSC, and SEM techniques
CUEVAS YAÑEZ, ERICK +7 more
core
Investigation of a new bis(carboxylate)triazole-based anchoring ligand for dye-sensitised solar cell chromophore complexes [PDF]
, 2017 A novel anchoring ligand for dye-sensitised solar cell chromophoric complexes, 1-(2,2’-bipyrid-4-yl)-1,2,3-triazole-4,5-dicarboxylic acid (dctzbpy), is described. The new dye complexes [Ru(bpy)2(dctzbpy)][PF6]2 (AS16), [Ir(ppy)2(dctzbpy)][PF6] (AS17) and
Abrahamsson +52 more
core +1 more source
Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach
The Chemical Record, EarlyView.This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos +3 more
wiley +1 more source
Crystal Structures of 2-Phenyl-2H-1,2,3-Triazol-4-Carbaldehyde, an Active a-Glycosidase Inhibition Agent, and (1-Phenyl-1H-1,2,3-Triazol-4-yl)Methyl Benzoate and (2-(4-Fluorophenyl)-2H-1,2,3-Triazole-4-yl)Methanol, Two Moderately Active Compounds [PDF]
, 2015 The use of the NCS crystallographic service at Southampton and the valuable assistance of the staff there are gratefully acknowledged.
da Silva, Fernando C. +4 more
core +1 more source
Zeitschrift für anorganische und allgemeine Chemie, Volume 652, Issue 2, 5 February 2026.Reactions of a triazole‐substituted 3H‐1,2,4‐diazaphosphole with electron‐rich cobalt and nickel complexes result in the selective cleavage of CC and CN bonds on the triazole, forming chelate complexes with the activated diazaphosphole ligand. The reactivity of the recently reported 3H‐1,2,4‐diazaphosphole 1 toward electron‐rich Ni and Co complexes ...
Sebastian Hauer +4 more
wiley +1 more source
Development of mixed metal metal-organic polyhedra networks, colloids, and MOFs and their pharmacokinetic applications [PDF]
, 2017 The coordination networking of discrete metal-organic polyhedra (MOPs) involving different ligands as well as metals is a challenging task due to the features of limited solubility and chemical stability of these polyhedra.
Ahmad, Nazir +6 more
core +2 more sources
Macromolecular Chemistry and Physics, Volume 227, Issue 3, 16 February 2026.LPSQ‐Macroalkoxyamines are used both as fillers and as initiators of styrene nitroxide‐mediated polymerization in the preparation of hybrid materials. The effects of this silicon‐based nanostructure on the thermal and viscoelastic properties of the final hybrid materials are presented.
Gahyeon Kim +5 more
wiley +1 more source
Monolayer doping of Si with improved oxidation resistance [PDF]
, 2016 In this article, the functionalization of planar silicon with arsenic- and phosphorus-based azides was investigated. Covalently bonded and well-ordered alkyne-terminated monolayers were prepared from a range of commercially available dialkyne precursors ...
Collins, Gillian +4 more
core +2 more sources