Results 111 to 120 of about 7,707 (195)
Tracker Nanocatalyst for Screening of Intracellular Copper‐Catalyzed Azide‐Alkyne Cycloadditions
Small, EarlyView.Development of a dual tracker nanocatalyst that represents a widely applicable advance for precise localization of catalytic reactions and real‐time screening and tuning of reaction conditions within cells. Abstract Intracellular copper‐catalyzed azide‐alkyne cycloaddition (CuAAC) offers immense potential for bioorthogonal chemistry, but its ...
Mónica Rodríguez‐Segura +5 more
wiley +1 more source
The Chemical Record, EarlyView.Systematic overview of pyrazole functionalization reactions from C‐5 to N−H. It covers different strategies, from traditional cross‐coupling of prefunctionalized pyrazoles to more efficient direct functionalizations. This review briefly and systematically overviews C–H and N–H functionalization reactions of pyrazoles, aimed at creating new CC and C ...
Karolina Dzedulionytė Müldür +3 more
wiley +1 more source
Zeitschrift für anorganische und allgemeine Chemie, EarlyView.Reactions of a triazole‐substituted 3H‐1,2,4‐diazaphosphole with electron‐rich cobalt and nickel complexes result in the selective cleavage of CC and CN bonds on the triazole, forming chelate complexes with the activated diazaphosphole ligand. The reactivity of the recently reported 3H‐1,2,4‐diazaphosphole 1 toward electron‐rich Ni and Co complexes ...
Sebastian Hauer +4 more
wiley +1 more source
Mannose‐Inspired Mesoionic Carbenes: Building Antitumor Palladium(II) Allyl Complexes
European Journal of Inorganic Chemistry, Volume 28, Issue 29, October 16, 2025.Mannose‐inspired mesoionic carbenes: Building antitumor palladium(II) allyl complexes. A series of palladium(II) complexes bearing mannose‐conjugated mesoionic carbenes has been synthesized and fully characterized. Several of these compounds exhibit potent and selective antiproliferative activity against cisplatin‐resistant ovarian and colon cancer ...
Giovanni Tonon +5 more
wiley +1 more source
Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways
ChemMedChem, Volume 20, Issue 20, October 15, 2025.Compound 2, identified through in‐house screening and derived from SP18, exhibits high affinity for BAG3, as demonstrated by Surface Plasmon Resonance and docking studies. It induces a dose‐dependent proapoptotic response in HeLa cells, evidenced by increased Annexin V/PI staining, underscoring the triazole scaffold as a promising platform for BAG3 ...
Dafne Ruggiero +10 more
wiley +1 more source
Angewandte Chemie, Volume 137, Issue 40, September 26, 2025.Fe‐triazolate (Fe(ta)2) and its metal‐substituted derivatives (Fe‐Metal(ta)2) MOFs are reported as dual‐function materials for light absorption and water oxidation catalysis in acidic media, achieving a highest photocurrent of 2 × 10−3 A cm−2 at bias + 1.4 V vs. Ag/AgCl.
Jully Patel +6 more
wiley +2 more sources
Effects on LuxR‐Regulated Bioluminescence of Cyclodextrin‐Acyl‐L‐Homoserine Lactone Hybrids
ChemBioChem, Volume 26, Issue 19, October 3, 2025.Cyclodextrin‐N‐acyl‐L‐Homoserine‐Lactone conjugates are synthetized, purified and fully characterized. The study of modulation of LuxR‐regulated bioluminescence production has demonstrated that one of the compounds exhibits not only the capacity to induce bioluminescence with an EC50 value of 64 µM, but also the ability to reduce bioluminescence with ...
Nicolas Tinet +5 more
wiley +1 more source
From Design to Outcome: The Role of Bi‐ and Multifunctional Ligands in Modern Therapeutics
Advanced Therapeutics, Volume 8, Issue 10, October 2025.This review highlights the innovative use of bi‐ and multifunctional ligands for precision therapeutics. From strategic linker design to bioorthogonal conjugation and nanoscaffold integration, these approaches enable precise targeting, high‐resolution receptor mapping, and enhanced drug delivery.
Célia Bouacha +2 more
wiley +1 more source
Semiconducting Nanomaterials for Intrinsically Stretchable Field‐Effect Transistors
Advanced Science, Volume 12, Issue 39, October 20, 2025.This review discusses intrinsically stretchable field‐effect transistors, highlighting recent developments in stretchable semiconducting nanomaterials and fabrication methods. Key material strategies and innovative deposition techniques enabling enhanced mechanical elasticity alongside reliable electronic properties are covered.
Seongmin Heo +4 more
wiley +1 more source
Advanced Energy Materials, Volume 15, Issue 37, October 7, 2025.This review presents metal‐organic frameworks (MOFs) as versatile electrolyte materials for next‐generation rechargeable batteries. Covering their evolution from basic separators to advanced single‐ion conducting solid electrolytes, it highlights strategic MOF designs that enhance ionic conductivity, mechanical robustness, selective ion transport, and ...
Zhe Huang +6 more
wiley +1 more source