Results 11 to 20 of about 19,712 (214)

Synthesis of Deuterated 1,2,3-Triazoles [PDF]

The Journal of Organic Chemistry, 2012
The copper-catalyzed azide-alkyne cycloaddition (CuAAC) is a highly effective method for the selective incorporation of deuterium atom into the C-5 position of the 1,2,3-triazole structure. Reactions of alkynes and azides can be conveniently carried out in a biphasic medium of CH(2)Cl(2)/D(2)O, using the CuSO(4)/Na ascorbate system. The mildness of the
Hari K, Akula, Mahesh K, Lakshman
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A Review on 1,2,3 - Triazole & Piperazine Derivatives with Various Biological Activities

Journal of Pharmaceutical Research, 2023
The largest family of organic molecules in organic chemistry are heterocyclic compounds. A heterocyclic compound is created when an oxygen, nitrogen, sulphur, or atom of a similar element is included in place of a carbon atom.
C Geethapriya Loganathan, Karthickeyan Krishnan, S D Vachala, Deeparani Urolagin, J Vijayakumar   +4 more
doaj   +1 more source

weak intermolecular interactions and catalytic ethylene oligomerisation [PDF]

, 2012
The ligands 1-(cyclohexyl)-4-(2-pyridyl)-1,2,3-triazole (1), 1-(2,6-diisopropylphenyl)-4-(2-pyridyl)-1,2,3-triazole (2), 1-(4-butoxyphenyl)-4-(2-pyridyl)-1,2,3-triazole (3) and 1-(methyl)-4-(2-pyridyl)-1,2,3-triazole (4) were synthesized by the Cu(I ...
Braunstein, Pierre, Sarkar, Biprajit, Schweinfurth, David, Su, Cheng-Yong, Wei, Shi-Chao   +4 more
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Regioselective synthesis of heterocyclic N-sulfonyl amidines from heteroaromatic thioamides and sulfonyl azides

Beilstein Journal of Organic Chemistry, 2020
N-Sulfonyl amidines bearing 1,2,3-triazole, isoxazole, thiazole and pyridine substituents were successfully prepared for the first time by reactions of primary, secondary and tertiary heterocyclic thioamides with alkyl- and arylsulfonyl azides.
Vladimir Ilkin, Vera Berseneva, Tetyana Beryozkina, Tatiana Glukhareva, Lidia Dianova, Wim Dehaen, Eugenia Seliverstova, Vasiliy Bakulev   +7 more
doaj   +1 more source

Synthesis and antitumoral activity of novel biaryl hydroxy-triazole and fluorene-triazole hybrids [PDF]

Exploration of Drug Science
Aim: The development of selective and potent antitumor agents remains a significant challenge. This study aimed to synthesize and evaluate biaryl hydroxy-1,2,3-triazoles and 9H-fluorene-1,2,3-triazole hybrids, inspired by previously identified bioactive ...
David Chafi Zeitune, Marcelo Folhadella Martins Faria Azevedo, Mariane Senna Rangel, Robert de Sousa Bastos, José de Brito Vieira Neto, Claudia do Ó Pessoa, Camilla Djenne Buarque   +6 more
doaj   +1 more source

Noncentrosymmetric Packings Influenced by Electronic Properties of Products of Click Reactions [PDF]

, 2014
Though 1,4-disubstituted 1,2,3-triazole rings have been utilized as electronic bridges in the solution phase, the use of a triazole ring to serve as an electronic bridge of small molecules in the crystalline state has been underdeveloped.
Baltrusaitis, J., Laird, R.C., MacGillivray, L.R., Nguyen, N.P., Rusch, S.F.   +4 more
core   +2 more sources

Antiproliferative Phenothiazine Hybrids as Novel Apoptosis Inducers against MCF-7 Breast Cancer

Molecules, 2018
We designed a series of novel phenothiazine-1,2,3-triazole hybrids by the molecular hybridization strategy and evaluated their antiproliferative activity against three cancer cell lines (MDA-MB-231, MDA-MB-468 and MCF-7).
Jun-Xia Zhang, Jiao-Mei Guo, Ting-Ting Zhang, Hong-Jun Lin, Nai-Song Qi, Zhen-Guo Li, Ji-Chun Zhou, Zhen-Zhong Zhang   +7 more
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Naphthalen-2-yl 1-(benzamido(diethoxyphosphoryl)methyl)-1H-1,2,3-triazole-4-carboxylate

Molbank, 2021
We have previously published new biheterocyclic phospohonic α-amino esters of the 1,2,3-triazole-benzimidazole and 1,2,3-triazole-carbazole type. The aim of the present paper was to describe a new phosponic aminoester bearing a triazole ring substituted ...
Serigne Abdou Khadir Fall, Sara Hajib, Oumaima Karai, Salaheddine Boukhssas, Younas Aouine, Mohamed Akhazzane, Brahim Labriti, Hassane Faraj, Anouar Alami   +8 more
doaj   +1 more source

Enantioselective synthesis of (+)-petromyroxol, enabled by rhodium-catalyzed denitrogenation and rearrangement of a 1-sulfonyl-1,2,3-triazole [PDF]

, 2015
Petromyroxol is a non-racemic mixture of enantiomeric oxylipids isolated from water conditioned with larval sea lamprey. The (+)-antipode exhibits interesting biological properties but only 1 mg was isolated from >100000 L of water.
Boyer, Alistair
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Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids

Acta Chimica Slovenica, 2020
(1-(2,4-Dioxo-1,2,3,4-tetrahydroquinolin-3-yl)-1H-1,2,3-triazol-4-yl)methyl acetates substituted on nitrogen atom of quinolinedione moiety with propargyl group or (1-substituted 1H-1,2,3-triazol-4-yl)methyl group, which are available from the appropriate 3-(4-hydroxymethyl-1H-1,2,3-triazol-1-yl)quinoline-2,4(1H,3H)-diones unsubstituted on quinolone ...
Milićević, David, Kimmel, Roman, Urankar, Damijana, Pevec, Andrej, Kosmrlj, Janez, Kafka, Stanislav   +5 more
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