Results 81 to 90 of about 19,900 (217)

Click chemistry: In vitro evaluation of glycosyl hybrid phosphorylated/thiophosphorylated 1,2,3-triazole derivatives as irreversible acetyl cholinesterase (AChE) inhibitors

Results in Chemistry, 2021
A novel series of phosphorylated/ thiophosphorylated glucosyl-1,2,3-triazole derivatives have been synthesized in three step process. The synthetic approach was progressed from the reaction of propargyl alcohol with dialkoxychlorophosphate/thiophosphate ...
B. Anjaneyulu, G.B. Dharma Rao, Tanima Bajaj   +2 more
doaj   +1 more source

Synthesis of xanthone-1,2,3-triazole dyads [PDF]

, 2015
Xanthones and 1,2,3-triazoles are known to exhibit several biological, pharmacological and biocidal properties[1]. The potential applications of these two classes of heterocycles led us to develop new strategies to synthesize xanthone-1,2,3-triazole ...
Albuquerque, Hélio, Cavaleiro, José, Santos, Clementina M.M., Silva, Artur   +3 more
core  

Regiospecific synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles via photochemically generated nitrile imine intermediates [PDF]

, 2014
The synthesis of N2-aryl 1,2,3-triazoles from 2,5-disubstituted tetrazoles was achieved under photochemical conditions. This simple and mild one-step reaction provides regiospecific access to 2,4,5-substituted 1,2,3-triazoles via a nitrile imine ...
Harris, Robert, Jamieson, Craig, Stewart, Sam   +2 more
core   +1 more source

Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Novel halogenated purines and pseudopurines with diverse aryl-substituted 1,2,3-triazoles were prepared. While p-(trifluoromethyl)-substituted 1,2,3-triazole in N-9 alkylated purine and 3-deazapurine was critical for strong albeit unselective activity on
Andrea Bistrović, Petra Grbčić, Anja Harej, Mirela Sedić, Sandra Kraljević-Pavelić, Sanja Koštrun, Janez Plavec, Damjan Makuc, Silvana Raić-Malić   +8 more
doaj   +1 more source

Bis‐Furans: A Sustainable Source of Diverse Molecular Architectures

European Journal of Organic Chemistry, Volume 29, Issue 10, 9 March 2026.
A concise synthetic route to diverse acyclic and heterocyclic compounds has been developed by combining hetero‐Diels–Alder reactions, DBU‐promoted ring openings, and Lewis base‐catalyzed annulations. Nitrosoalkenes reacted with furan derivatives to form 4a,7a‐dihydro‐4H‐furo[2,3‐e][1,2]oxazines, which underwent DBU‐promoted rearrangements to 6H‐1,2 ...
Ana L. Cardoso, José A. Paixão, Teresa M. V. D. Pinho e Melo   +2 more
wiley   +1 more source

Impact of Surface Functionalization on NV Quantum Properties: Implications for Biosensing with Fluorescent Nanodiamonds

Advanced Functional Materials, Volume 36, Issue 25, 26 March 2026.
Fluorescent nanodiamonds (fNDs) have emerged as an invaluable quantum sensing platform for biological and biochemical systems. This paper investigates the influence of common surface functionalization strategies for bioconjugation on the quantum properties of nitrogen vacancy (NV) centers in nanodiamonds.
Anja Sadžak, Iván Pérez, Mateja Guimarães, Lukas Spantzel, Fedor Jelezko, Michael Börsch, Anke Krueger   +6 more
wiley   +1 more source

Phenyl 1,2,3-triazole-thymidine ligands stabilize G-quadruplex DNA, inhibit DNA synthesis and potentially reduce tumor cell proliferation over 3'-azido deoxythymidine.

PLoS ONE, 2013
Triazoles are known for their non-toxicity, higher stability and therapeutic activity. Few nucleoside (L1, L2 and L3) and non-nucleoside 1,2,3-triazoles (L4-L14) were synthesised using click chemistry and they were screened for tumor cell cytotoxicity ...
Jerald Mahesh Kumar, Mohammed M Idris, Gunda Srinivas, Pallerla Vinay Kumar, Vuppalapaty Meghah, Mitta Kavitha, Chada Raji Reddy, Prathama S Mainkar, Biswajit Pal, Srivari Chandrasekar, Narayana Nagesh   +10 more
doaj   +1 more source

Investigation of a new bis(carboxylate)triazole-based anchoring ligand for dye-sensitised solar cell chromophore complexes [PDF]

, 2017
A novel anchoring ligand for dye-sensitised solar cell chromophoric complexes, 1-(2,2’-bipyrid-4-yl)-1,2,3-triazole-4,5-dicarboxylic acid (dctzbpy), is described. The new dye complexes [Ru(bpy)2(dctzbpy)][PF6]2 (AS16), [Ir(ppy)2(dctzbpy)][PF6] (AS17) and
Abrahamsson, Alessandro Sinopoli, Altobello, Altobello, Andrae, Ardo, Baranoff, Becke, Brennaman, Buttner, Christopher J. Wood, De Angelis, Elizabeth A. Gibson, Fallahpour, Ferrere, Fiona A. Black, Geary, Gennari, Gillaizeau-Gauthier, Goodenough, Hagfeldt, Hasselmann, Hasselmann, Heuer, Ji, Juris, Klamt, Krishnan, Lim, Lo, Lodge, Massin, Mayo, Mishra, Mishra, Murakami, Nattestad, Nazeeruddin, O'Regan, Odobel, Odobel, Paul I. P. Elliott, Pellegrin, Runge, Schweinfurth, Sinopoli, Stephens, Uppal, Valiev, Wang, Wood, Yao, Yella   +52 more
core   +1 more source

Expanding the Chemical Space of Cyclic Polyphthalaldehyde via Post‐Functionalization

Advanced Science, Volume 13, Issue 13, 3 March 2026.
In this work, we developed a post‐functionalization approach to achieve water‐soluble cyclic polyphthalaldehyde (cPPA) polymers via click chemistry. ABSTRACT Cyclic polyphthalaldehydes (cPPAs) are hydrophobic cyclic polymers with stimuli‐responsive depolymerization property. The introduction of hydrophilic functionalities to cPPAs is challenging due to
Liting He, Haiyan Zhou, Qiushi Chen, Xing Guo, Han Liu, Xuechen Li   +5 more
wiley   +1 more source

Recent advances in the synthesis of triazole derivatives [PDF]

, 2015
Triazole ring system has attracted a continuously growing interest of synthetic organic chemists and those dealing with the medicinal compounds due to its versatile potential to interact with biological systems.
Ahmad, Matloob, Aslam, Sana, Jawwad, Muhammad, Khan, Imran Ahmad, Mansha, Asim, Raza Naqvi, Syed Ali, Zahoor, Fawad   +6 more
core