1,2,3-Triazoles as Biomimetics in Peptide Science. [PDF]
Molecules, 2021 Natural peptides are an important class of chemical mediators, essential for most vital processes. What limits the potential of the use of peptides as drugs is their low bioavailability and enzymatic degradation in vivo.
Agouram N, El Hadrami EM, Bentama A.
europepmc +6 more sources
A recent overview on the synthesis of 1,4,5-trisubstituted 1,2,3-triazoles
Beilstein Journal of Organic Chemistry, 2021 Diverse strategies for the efficient and attractive synthesis of a wide variety of relevant 1,4,5-trisubstituted 1,2,3-triazole molecules are reported. The synthesis of this category of diverse fully functionalized 1,2,3-triazoles has become a necessary ...
Pezhman Shiri +2 more
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Silver-Catalyzed Cascade Cyclization of Amino-NH-1,2,3-Triazoles with 2-Alkynylbenzaldehydes: An Access to Pentacyclic Fused Triazoles [PDF]
Molecules, 2022 An operationally simple Ag(I)-catalyzed approach for the synthesis of isoquinoline and quinazoline fused 1,2,3-triazoles was developed by a condensation and amination cyclization cascade of amino-NH-1,2,3-triazoles with 2-alkynylbenzaldehydes involving ...
Shuitao Zhang +4 more
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Differentiation between Isomeric 4,5-Functionalized 1,2,3-Thiadiazoles and 1,2,3-Triazoles by ESI-HRMS and IR Ion Spectroscopy [PDF]
Molecules, 2023 A large variety of 1,2,3-thiadiazoles and 1,2,3-triazoles are used extensively in modern pure and applied organic chemistry as important structural blocks of numerous valuable products.
Dmitrii M. Mazur +6 more
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Copper-Catalyzed Synthesis of 4-CF3-1,2,3-Triazoles: An Efficient and Facile Approach via Click Reaction [PDF]
MoleculesIncorporation of a trifluoromethyl group with 1,2,3-triazoles motifs was described. We explored a click reaction approach for regioselective synthesis of 1-susbstituted-4-trifluoromethyl-1,2,3-triazoles in which 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU ...
Tinghong Tang +5 more
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4,5-Bis(arylethynyl)-1,2,3-triazoles—A New Class of Fluorescent Labels: Synthesis and Applications [PDF]
Molecules, 2022 Cu-catalyzed 1,3-dipolar cycloaddition of ethyl 2-azidoacetate to iodobuta-1,3-diynes and subsequent Sonogashira cross-coupling were used to synthesize a large series of new triazole-based push–pull chromophores: 4,5-bis(arylethynyl)-1H-1,2,3-triazoles ...
Anastasia I. Govdi +7 more
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Fe3O4@HA-Cu(OAc)2 nanocomposite as a nanomagnetic water-compatible catalyst for efficient synthesis of 1,2,3-triazoles in water [PDF]
Scientific ReportsA new humic acid-based nanomagnetic copper(II) composite was prepared and used as an eco-friendly recoverable catalyst for synthesizing 1,4-disubstituted 1,2,3-triazoles.
Beheshteh Arjmandzadeh, Abbas Ali Jafari
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Журнал органічної та фармацевтичної хімії, 2022 Aim. To analyze and summarize the synthetic potential of 1,2,3-triazole-4(5)-amines as efficient building blocks in the synthesis of triazolo-annulated pyridine, azine and azepine systems. Results and discussion.
Natalia O. Syrota +3 more
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ACS Omega, 2021 A new series of 1,2,3-triazole hybrids containing either 2- or 4-hydroxyphenyl benzothiazole (2- or 4-HBT) and naphthalen-1-ol or 8-hydroxyquinoline (8-HQ) was synthesized in high yields and fully characterized.
Nidhi Nehra, Ram Kumar Tittal, V. Ghule
semanticscholar +1 more source
Overview of 1,5-Selective Click Reaction of Azides with Alkynes or Their Synthetic Equivalents
Molecules, 2023 Nowadays, the click reaction of azides with alkynes has evolved rapidly and become one of the most efficient methods to synthesize 1,2,3-triazoles, which are an important class of N-containing heterocycles.
Yaqi Zhao +3 more
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