Results 1 to 10 of about 251 (118)

Xanthone-1,2,4-triazine and Acridone-1,2,4-triazine Conjugates: Synthesis and Anticancer Activity

Pharmaceuticals, 2023
A total of 21 novel xanthone and acridone derivatives were synthesized using the reactions of 1,2,4-triazine derivatives with 1-hydroxy-3-methoxy-10-methylacridone, 1,3-dimethoxy-, and 1,3-dihydroxanthone, followed by optional dihydrotiazine ring ...
Sougata Santra, Ainur D. Sharapov, Ramil F. Fatykhov, Anastasya P. Potapova, Igor A. Khalymbadzha, Maria I. Valieva, Dmitry S. Kopchuk, Grigory V. Zyryanov, Alexander S. Bunev, Vsevolod V. Melekhin, Vasiliy S. Gaviko, Andrey A. Zonov   +11 more
doaj   +4 more sources

Energetic salt of guanidinium 3,7-Bis(dinitromethylene)-octahydro-[1,2,4]-triazino-[6,5-e][1,2,4]triazine and its crystal structure [PDF]

ITM Web of Conferences, 2022
Energetic salt of guanidinium 3,7-Bis(dinitromethylene)-octahydro-[1,2,4]-triazino-[6,5-e][1,2,4]triazine(1) was prepared through the reaction of 3,7-Bis(dinitromethylene)-octahydro-[1,2,4]-triazino-[6,5-e][1,2,4]triazine with guanidinium carbonate.
Zhou Yifei, Gao Haixiang
doaj   +1 more source

Revisiting the Synthesis of Functionally Substituted 1,4-Dihydrobenzo[e][1,2,4]triazines

Molecules, 2022
A series of novel 1,4-dihydrobenzo[1,2,4][e]triazines bearing an acetyl or ester moiety as a functional group at the C(3) atom of the 1,2,4-triazine ring were synthesized.
Margarita A. Epishina, Alexander S. Kulikov, Leonid L. Fershtat   +2 more
doaj   +1 more source

Synthesis of functionalized imidazo[4,5-e]thiazolo[3,2-b]triazines by condensation of imidazo[4,5-e]triazinethiones with DMAD or DEAD and rearrangement to imidazo[4,5-e]thiazolo[2,3-c]triazines

Beilstein Journal of Organic Chemistry, 2021
Two series of functionalized imidazothiazolotriazine derivatives were synthesized via the condensation of imidazo[4,5-e]-1,2,4-triazine-3-thiones with acetylenedicarboxylic acid dimethyl and diethyl esters (DMAD and DEAD) and subsequent base-catalyzed ...
Alexei N. Izmest’ev, Dmitry B. Vinogradov, Natalya G. Kolotyrkina, Angelina N. Kravchenko, Galina A. Gazieva   +4 more
doaj   +1 more source

Synthesis of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines via a base-induced rearrangement of functionalized imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazines

Beilstein Journal of Organic Chemistry, 2023
A series of imidazo[4,5-e][1,3]thiazino[2,3-c][1,2,4]triazines was synthesized via a cascade sequence of hydrolysis and skeletal rearrangement of imidazo[4,5-e]thiazolo[2,3-c][1,2,4]triazin-7(8H)-ylidene)acetic acid esters in methanol upon treatment with
Dmitry B. Vinogradov, Alexei N. Izmest’ev, Angelina N. Kravchenko, Yuri A. Strelenko, Galina A. Gazieva   +4 more
doaj   +1 more source

Bioactive Pyrrolo[2,1-f][1,2,4]triazines: Synthesis, Molecular Docking, In Vitro Cytotoxicity Assay and Antiviral Studies

Chemistry, 2023
A series of 2,4-disubstituted pyrrolo[2,1-f][1,2,4]triazines containing both aryl and thienyl substituents were synthesized by exploiting the 1,3-cycloaddition reaction of N(1)-ethyl-1,2,4-triazinium tetrafluoroborates with dimethyl ...
Nataliya N. Mochulskaya, Svetlana K. Kotovskaya, Ilya I. Butorin, Mikhail V. Varaksin, Valery N. Charushin, Vladimir L. Rusinov, Yana L. Esaulkova, Alexander V. Slita, Polina A. Ilyina, Vladimir V. Zarubaev   +9 more
doaj   +1 more source

Review of the Synthesis and Anticancer Properties of Pyrazolo[4,3-e][1,2,4]triazine Derivatives

Molecules, 2020
This review focuses on the cytotoxic effect of new synthetic pyrazolo[4,3-e][1,2,4]triazine derivatives against different tumor cell lines. Some annulated pyrazolotriazines i.e., pyrazolo[4,3-e][1,2,4]triazolo[4,3-b][1,2,4]triazines and pyrazolo[4,3-e ...
Zofia Bernat, Anna Szymanowska, Mateusz Kciuk, Katarzyna Kotwica-Mojzych, Mariusz Mojzych   +4 more
doaj   +1 more source

A convenient synthetic approach to 5-(het)arylhydrazine substituted 1,2,4-triazines

Chimica Techno Acta, 2020
A convenient synthesis of 1,2,4-triazines bearing the moieties of (hetero)arylhydrazines at the position of C5 of the 1,2,4-triazine core is reported.
A. P. Krinochkin, M. R. Guda, A. Rammohan, D. S. Kopchuk, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin   +6 more
doaj   +1 more source

SYNTHESIS, AND BIOLOGICAL EVALUATION OF NEWLY SUNTHESIZED TRIAZOLOTRIAZINES AND TRIAZOLOTRAIZINES DERIVATIVES [PDF]

مجلة جامعة الانبار للعلوم الصرفة, 2018
Novel 8-(4-fluorophenyl)-6,6-diphenyl-3-(pyrimidin-4-yl) -5,6,7,8-tetrahydro-6l5-[1,2,4]triazolo [4,3-a][1,3,5]diazaphosphinin-6-ol(5),8-(4-fluorophenyl)-6-phenyl-3-(pyrimidin-4-yl)-7,8-dihydro [1,2,4]triazolo [4,3-b][1,2,4]triazine (6), 8-(4 ...
Hameed M. Mohammed
doaj   +1 more source

2-(5,6-Diphenyl-1,2,4-Triazin-3-yl)pyridinium Dichloroiodate (I)

Molbank, 2023
2-(5,6-diphenyl-1,2,4-triazin-3-yl)pyridinium dichloroiodate (I) (1) was synthesized by reacting 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine with ICl in dichloromethane solution.
M. Carla Aragoni, Vito Lippolis, Annalisa Mancini, Anna Pintus, Enrico Podda, James B. Orton, Simon J. Coles, Massimiliano Arca   +7 more
doaj   +1 more source